Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   NYE32_RS07095 Genome accession   NZ_CP150201
Coordinates   1584845..1586716 (-) Length   623 a.a.
NCBI ID   WP_339156948.1    Uniprot ID   -
Organism   Streptococcus sp. FSL R7-0248     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1579845..1591716
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE32_RS07060 (NYE32_07060) rimM 1580227..1580745 (-) 519 WP_060971504.1 ribosome maturation factor RimM -
  NYE32_RS07075 (NYE32_07075) - 1581440..1582084 (-) 645 WP_002891417.1 response regulator transcription factor -
  NYE32_RS07080 (NYE32_07080) - 1582074..1583084 (-) 1011 WP_002891418.1 sensor histidine kinase -
  NYE32_RS07085 (NYE32_07085) liaF 1583081..1583779 (-) 699 WP_339156946.1 cell wall-active antibiotics response protein LiaF -
  NYE32_RS07090 (NYE32_07090) - 1583942..1584700 (-) 759 WP_201041407.1 potassium channel family protein -
  NYE32_RS07095 (NYE32_07095) stkP/pknB 1584845..1586716 (-) 1872 WP_339156948.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  NYE32_RS07100 (NYE32_07100) - 1586716..1587453 (-) 738 WP_037598574.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  NYE32_RS07105 (NYE32_07105) rsmB 1587497..1588819 (-) 1323 WP_339156949.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  NYE32_RS07110 (NYE32_07110) fmt 1588809..1589744 (-) 936 WP_339156950.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67868.60 Da        Isoelectric Point: 6.5787

>NTDB_id=966175 NYE32_RS07095 WP_339156948.1 1584845..1586716(-) (stkP/pknB) [Streptococcus sp. FSL R7-0248]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKTVAAEPSEPTPA
PSKQPRKKTTPAKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGAGFKVGEVKEVE
DDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGEI
LSQSPGKNKSFNPKDSKAKIKFRVATPKIVTMPDVTGLTVSTAVQTLNRKNISSSSIEYHDYNTGAKLDKDKIPSSTEVL
YQDPQAGTSVDGTVILYVSVATASSNLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=966175 NYE32_RS07095 WP_339156948.1 1584845..1586716(-) (stkP/pknB) [Streptococcus sp. FSL R7-0248]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATTCTGGATAATGAAAAAGTGGCTATTAAGGTACTTCGTACCAATTACCAAACTGATCAGGTGG
CTGTGGCCCGTTTCCAACGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGT
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTATGTGGACGGTTCGGACTTGAAGAAATACATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTCCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCGCAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCGGAGACTAGTCTAACTCAAACAAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
TAAAGCGACTATCCAAAGTGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GTGATAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAACCACTACCATCGATTTTGGCAGAGAACCGTAATGTTCCC
CAAGCTTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTACAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGTGATGCCAAGGTAGTCTTTGATGATATGACGGATACTAAGACCT
TGCCGAAGGTTGATCCAGTTCCATCAGCAAGTCTTGAGAAAAAAACCGTTGCTGCTGAACCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAACTTCTTCTCAACCTTACTCAAGGTTTT
CCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCTTATTTAGTCTTTACCAATCCTGATAATGTCCAAGTACCTAATG
TGGTCGGTCAGGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTCAAAGAAGTGGAA
GATGACTCTGTCGATACGGGTAAGGTCATCAAGACCGATCCTACAGCTGGAACCACACGAAAAGAAGGATCAAGCATTGA
TGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAGGGTAAAAACTATAAGGATGCCATTGAGGATT
TAACTTCGAATTATGGTGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAAATC
CTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCTAAGATTAAGTTCCGTGTGGCAACGCC
TAAGATAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCAGTTCAAACCTTGAATCGTAAGAATATCTCAA
GTAGTAGCATCGAGTACCACGACTATAATACTGGTGCTAAGTTAGATAAGGATAAGATTCCTAGCAGTACGGAGGTCCTT
TATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAGTTCAAACCT
TCAGTCAAGCTCAAGTAGTACGACACATTCGTCATCAACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAACCT
CGACAGAGGCTACTCACACAGAACTACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(369-431)

PASTA domain (PASTA)

(440-504)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.878

100

0.99
  pknB Streptococcus mutans UA159

67.159

86.998

0.584
  stkP Streptococcus pneumoniae TIGR4

58.824

79.133

0.465
  stkP Streptococcus pneumoniae D39

58.621

79.133

0.464
  stkP Streptococcus pneumoniae R6

58.621

79.133

0.464
  stkP Streptococcus pneumoniae Rx1

58.418

79.133

0.462

Multiple sequence alignment