Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NYE32_RS01425 Genome accession   NZ_CP150201
Coordinates   271143..271832 (+) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus sp. FSL R7-0248     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 266143..276832
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE32_RS01400 (NYE32_01400) - 266376..267206 (+) 831 WP_037599013.1 energy-coupling factor transporter transmembrane component T -
  NYE32_RS01405 (NYE32_01405) - 267295..267966 (-) 672 WP_002889958.1 TrkA family potassium uptake protein -
  NYE32_RS01410 (NYE32_01410) - 268006..269370 (-) 1365 WP_082160342.1 potassium transporter TrkG -
  NYE32_RS01415 (NYE32_01415) rsmG 269439..270152 (-) 714 WP_037599017.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  NYE32_RS01420 (NYE32_01420) - 270451..270987 (+) 537 WP_037599019.1 YceD family protein -
  NYE32_RS01425 (NYE32_01425) covR 271143..271832 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  NYE32_RS01430 (NYE32_01430) covS 271829..273358 (+) 1530 WP_073949294.1 HAMP domain-containing histidine kinase Regulator
  NYE32_RS01435 (NYE32_01435) nrdR 273480..273959 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  NYE32_RS01440 (NYE32_01440) - 273956..275131 (+) 1176 WP_037599021.1 DnaD domain protein -
  NYE32_RS01445 (NYE32_01445) dnaI 275135..276037 (+) 903 WP_037599023.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=966149 NYE32_RS01425 WP_002883757.1 271143..271832(+) (covR) [Streptococcus sp. FSL R7-0248]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=966149 NYE32_RS01425 WP_002883757.1 271143..271832(+) (covR) [Streptococcus sp. FSL R7-0248]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGTGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCCCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGTGGTGCTGATGACTATATTGTAAAACCTTTTGCGATTGA
AGAACTATTGGCACGTATTCGAGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCTAAAGCGTCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGATGCAATCGAAACAAACGTTGTAGATGTCTATATTCGTTACTTGCGTGGAAAAATCGATGTTCCAGGTAAGGAAT
CATACATTCAAACAGTGCGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment