Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   NYE32_RS01430 Genome accession   NZ_CP150201
Coordinates   271829..273358 (+) Length   509 a.a.
NCBI ID   WP_073949294.1    Uniprot ID   A0A6N3AKZ1
Organism   Streptococcus sp. FSL R7-0248     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 266829..278358
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE32_RS01405 (NYE32_01405) - 267295..267966 (-) 672 WP_002889958.1 TrkA family potassium uptake protein -
  NYE32_RS01410 (NYE32_01410) - 268006..269370 (-) 1365 WP_082160342.1 potassium transporter TrkG -
  NYE32_RS01415 (NYE32_01415) rsmG 269439..270152 (-) 714 WP_037599017.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  NYE32_RS01420 (NYE32_01420) - 270451..270987 (+) 537 WP_037599019.1 YceD family protein -
  NYE32_RS01425 (NYE32_01425) covR 271143..271832 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  NYE32_RS01430 (NYE32_01430) covS 271829..273358 (+) 1530 WP_073949294.1 HAMP domain-containing histidine kinase Regulator
  NYE32_RS01435 (NYE32_01435) nrdR 273480..273959 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  NYE32_RS01440 (NYE32_01440) - 273956..275131 (+) 1176 WP_037599021.1 DnaD domain protein -
  NYE32_RS01445 (NYE32_01445) dnaI 275135..276037 (+) 903 WP_037599023.1 primosomal protein DnaI -
  NYE32_RS01450 (NYE32_01450) der 276142..277452 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  NYE32_RS01455 (NYE32_01455) - 277516..278145 (+) 630 WP_037599025.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58080.49 Da        Isoelectric Point: 5.1853

>NTDB_id=966150 NYE32_RS01430 WP_073949294.1 271829..273358(+) (covS) [Streptococcus sp. FSL R7-0248]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLFSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTIPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=966150 NYE32_RS01430 WP_073949294.1 271829..273358(+) (covS) [Streptococcus sp. FSL R7-0248]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTAGTTGTTGTTTTCTCGGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ATAATACAATTTCGAAAGTTGTTACTTATATCGAAAAGGACTGGGATTCTGATGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCTAAAAATATCTATGCATCAATCATTAATGGTGTGCTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATTTTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAAAACACAGACTCTCCTCCAGGCATGTCTGAAGTAAACAAACTGAAGTCAGTGTCCTATAAAGGAAAGCGTGGTTTC
TTACTGCAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGTTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTGAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCAACTG
TGGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGCCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTACGTACGCCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAGAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAATGA
TACGTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTTGAGAGCTCAGAGCGTCCAGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAC
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATCAAGGCTCTGGAAGATGAAATGTTGGTACAAGTACA
AGATAATGGTGAAGGGATTTCTAAAGAAGATATTGAGCATATCTTTGAACGCTTCTATCGTTCAGATAAGGCACGTAATC
GTACGACAACACAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCGGATGGAGAAACGACGATACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N3AKZ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.411

100

0.994

Multiple sequence alignment