Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NYE32_RS00840 Genome accession   NZ_CP150201
Coordinates   154592..155341 (+) Length   249 a.a.
NCBI ID   WP_070576236.1    Uniprot ID   A0AAW7PC97
Organism   Streptococcus sp. FSL R7-0248     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 149592..160341
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE32_RS00820 (NYE32_00820) - 150607..151347 (-) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -
  NYE32_RS00825 (NYE32_00825) - 151347..152894 (-) 1548 WP_339157047.1 ABC transporter substrate-binding protein/permease -
  NYE32_RS00830 (NYE32_00830) - 153100..153954 (+) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  NYE32_RS00835 (NYE32_00835) - 154014..154385 (-) 372 WP_060973232.1 DUF3021 family protein -
  NYE32_RS00840 (NYE32_00840) mecA 154592..155341 (+) 750 WP_070576236.1 adaptor protein MecA Regulator
  NYE32_RS00845 (NYE32_00845) - 155345..156502 (+) 1158 WP_037598909.1 MraY family glycosyltransferase -
  NYE32_RS00850 (NYE32_00850) sufC 156664..157434 (+) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  NYE32_RS00855 (NYE32_00855) sufD 157471..158733 (+) 1263 WP_013989976.1 Fe-S cluster assembly protein SufD -
  NYE32_RS00860 (NYE32_00860) - 158787..160019 (+) 1233 WP_339157048.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29084.69 Da        Isoelectric Point: 4.0534

>NTDB_id=966142 NYE32_RS00840 WP_070576236.1 154592..155341(+) (mecA) [Streptococcus sp. FSL R7-0248]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKNVPVEGSELYKLGNVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=966142 NYE32_RS00840 WP_070576236.1 154592..155341(+) (mecA) [Streptococcus sp. FSL R7-0248]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTACACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGCGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGACCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCAGATATGGACGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCTCT
TGAAGGTAACTTTATGGACAAGGGGGATATCGAAGCACACCATAAGCTCGAAGAACTTGAGAAGACCTTGGAAGAAGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTACACAAGGCTTGAAGAATGTACCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GAATGTCTACTATATGACAATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATTTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

94.378

100

0.944
  mecA Streptococcus thermophilus LMG 18311

93.574

100

0.936
  mecA Streptococcus mutans UA159

59.426

97.992

0.582
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474

Multiple sequence alignment