Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   NYE79_RS08025 Genome accession   NZ_CP150168
Coordinates   1608656..1610554 (-) Length   632 a.a.
NCBI ID   WP_251463947.1    Uniprot ID   -
Organism   Streptococcus sp. FSL W8-0197     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1603656..1615554
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE79_RS08000 (NYE79_08000) - 1603786..1604751 (+) 966 WP_000225990.1 LacI family DNA-binding transcriptional regulator -
  NYE79_RS08005 (NYE79_08005) - 1604788..1606062 (-) 1275 WP_049519323.1 hydroxymethylglutaryl-CoA reductase, degradative -
  NYE79_RS08010 (NYE79_08010) - 1606062..1607234 (-) 1173 WP_049519472.1 hydroxymethylglutaryl-CoA synthase -
  NYE79_RS08015 (NYE79_08015) - 1607353..1607808 (-) 456 WP_000176909.1 threonine/serine exporter family protein -
  NYE79_RS08020 (NYE79_08020) - 1607810..1608568 (-) 759 WP_251463945.1 threonine/serine exporter family protein -
  NYE79_RS08025 (NYE79_08025) stkP 1608656..1610554 (-) 1899 WP_251463947.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  NYE79_RS08030 (NYE79_08030) - 1610551..1611291 (-) 741 WP_000401527.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  NYE79_RS08035 (NYE79_08035) rsmB 1611307..1612620 (-) 1314 WP_251463949.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  NYE79_RS08040 (NYE79_08040) fmt 1612613..1613548 (-) 936 WP_216728862.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 632 a.a.        Molecular weight: 68869.18 Da        Isoelectric Point: 9.1469

>NTDB_id=964623 NYE79_RS08025 WP_251463947.1 1608656..1610554(-) (stkP) [Streptococcus sp. FSL W8-0197]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQPK
KPTQPVAEPAPAPKPAKKRKFKARYMILLASLLLVAASLIWILSRTPATIPIPDVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTDVVAELKEKKVPENLIKMEEEESSESEPGTI
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPSYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTPEGTKEGTVVDQTPR
AGELVDLASTRIKLSIYKPKTPPSTSSSNPAQRGNQGSPTSPNQGNQQGNQQGNTPSSSSSNNEGSRESSRD

Nucleotide


Download         Length: 1899 bp        

>NTDB_id=964623 NYE79_RS08025 WP_251463947.1 1608656..1610554(-) (stkP) [Streptococcus sp. FSL W8-0197]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACGGACCCGATTG
CTGTGGCACGTTTCCAGCGGGAAGCGAGGGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTACCTAGCTATGGAATACGTAGCAGGCCTTGACCTCAAGCGTTATATCAAAGAACACTATCC
TCTTTCAAATGAAGAAGCAGTTCGGATCATGGGGCAAATCCTCTTGGCCATGCGCTTAGCCCATACTCGAGGAATTGTTC
ACCGGGATTTGAAACCTCAAAATATCCTCTTGACACCTGACGGCACAGCTAAGGTCACGGACTTTGGGATTGCAGTAGCC
TTTGCGGAGACCAGTCTGACCCAGACGAACTCAATGCTGGGTTCTGTTCATTATTTGTCACCTGAGCAAGCACGTGGTTC
TAAAGCGACCTTCCAGAGTGATATCTATGCAATGGGGATTATCTTCTATGAGATGCTAACGGGACATATCCCTTATGATG
GGGATAGTGCGGTTACGATTGCCCTCCAGCATTTCCAGAAGCCACTACCGTCCGTCATAGCTGAAAATCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATCAAGGCAACTGCTAAGAAGTTGTCAGACCGTTATCAGTCTGTTTCAGAAATGTATGT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGGAATGAACCGAAACTGGTCTTTGACGATGCGAGTAAGGCAGACACTA
AGACTTTACCTAAAGTTCCACAAAGTACACTGACATCGATTCCTAAAGCTCCGGCGCAAGAAGAACGCCCTCAGCCAAAG
AAACCAACTCAACCAGTGGCAGAGCCGGCTCCAGCTCCAAAGCCAGCCAAGAAACGGAAGTTTAAGGCTCGTTATATGAT
TCTTTTGGCTAGTCTTCTATTGGTTGCGGCCTCTTTAATCTGGATTTTGTCTAGAACACCTGCAACGATTCCCATTCCTG
ATGTGGCTGGACAAACCGTTGCAGAGGCCAAAGAAGCACTCAAAAAATCCAAGTTTGAAGCTGGTGAAGAGAAATCGGAG
GCTAGCGATACAGTAGCGGAAGGACGCGTTATTCGAACGGATCCAGAAGCTGGTAGTGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGGAAGCAATCTTTCCAATTGAGCAATTACGTCGGACGTAAGTATACGGATGTTGTAGCCG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAGCGAAAGTGAACCTGGAACCATC
CTTAGACAGACTCCTGCTTCGGGTTCGACTTATGATCTCTCAAAAGCTACTACGATTACCTTAACAGTAGCTAAGAAGGT
GACTAGTGTCAGCATGCCTAGCTACATCGGCTCAAGTCTTGAATTTACTAAGAATAATCTGACTCAGATTGTCGGTGTAA
AAGAGGCTAATATCGAAGTTGTTGAAGTATCGACTCCTGAAGGAACAAAAGAGGGCACGGTTGTAGATCAAACGCCAAGA
GCAGGAGAACTGGTTGATCTCGCAAGTACGCGTATCAAACTTTCCATCTACAAACCAAAAACACCACCATCAACTTCATC
TTCTAATCCTGCCCAACGTGGAAACCAGGGTTCTCCTACAAGTCCAAACCAGGGGAACCAACAAGGAAATCAACAAGGGA
ATACTCCTTCTAGCAGTTCATCCAATAATGAAGGATCTCGCGAAAGTTCTCGAGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(372-432)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-578)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.669

92.722

0.729
  stkP Streptococcus pneumoniae D39

78.328

92.722

0.726
  stkP Streptococcus pneumoniae R6

78.328

92.722

0.726
  stkP Streptococcus pneumoniae Rx1

78.157

92.722

0.725
  pknB Streptococcus mutans UA159

56.153

91.297

0.513
  stkP/pknB Streptococcus salivarius strain HSISS4

53.584

92.722

0.497

Multiple sequence alignment