Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   NYE79_RS04840 Genome accession   NZ_CP150168
Coordinates   960184..960891 (+) Length   235 a.a.
NCBI ID   WP_049478212.1    Uniprot ID   A0AAW7W6S8
Organism   Streptococcus sp. FSL W8-0197     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 955184..965891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE79_RS04815 (NYE79_04815) - 955482..956153 (+) 672 WP_000151556.1 GTP pyrophosphokinase family protein -
  NYE79_RS04820 (NYE79_04820) - 956137..956955 (+) 819 WP_000799063.1 NAD kinase -
  NYE79_RS04825 (NYE79_04825) - 956952..957848 (+) 897 WP_216728353.1 RluA family pseudouridine synthase -
  NYE79_RS04830 (NYE79_04830) pta 957892..958866 (+) 975 WP_049518760.1 phosphate acetyltransferase -
  NYE79_RS04835 (NYE79_04835) mutY 958949..960127 (+) 1179 WP_049478211.1 A/G-specific adenine glycosylase -
  NYE79_RS04840 (NYE79_04840) micA 960184..960891 (+) 708 WP_049478212.1 response regulator YycF Regulator
  NYE79_RS04845 (NYE79_04845) micB 960884..962233 (+) 1350 WP_000568721.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NYE79_RS04850 (NYE79_04850) vicX 962235..963044 (+) 810 WP_038806131.1 MBL fold metallo-hydrolase Regulator
  NYE79_RS04855 (NYE79_04855) - 963153..965045 (+) 1893 WP_339293828.1 Eco57I restriction-modification methylase domain-containing protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27019.88 Da        Isoelectric Point: 4.6177

>NTDB_id=964608 NYE79_RS04840 WP_049478212.1 960184..960891(+) (micA) [Streptococcus sp. FSL W8-0197]
MKKILIVDDEKPISDIIKFNMVKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKSIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDSQESDEKKAQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=964608 NYE79_RS04840 WP_049478212.1 960184..960891(+) (micA) [Streptococcus sp. FSL W8-0197]
ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGTCAAGGAAGGTTATGA
AGTTGTTACAGCCTTCAATGGTCGTGAGGCAATCGAGTTATTTGAAGCAGAGCAACCAGATATTATTATTCTCGACTTGA
TGCTACCTGAAATTGATGGTTTAGAAGTGGCTAAATCTATTCGTAAGACTAGTAGCGTGCCGATTATCATGCTCTCAGCT
AAGGATAGCGAGTTTGACAAGGTTATTGGTTTAGAGTTAGGTGCAGATGATTATGTTACAAAGCCTTTCTCAAACCGTGA
GTTGCAAGCACGTGTTAAGGCTCTGCTTCGTCGTACAGACCTAGTTTCTGTGGATAGCCAAGAGTCTGATGAGAAGAAGG
CGCAACCGTTACAAATCGGTGATTTGGAAATCGTTCCAGATGCTTACGTGGCTAAGAAATATGGTGAGGAGTTAGATTTG
ACCCACCGTGAGTTTGAACTCTTGTATCACTTGGCATCTCATATTGGTCAAGTGATTACGCGTGAACACTTGCTTGAGAC
TGTATGGGGTTATGACTATTTTGGTGATGTTCGTACTGTGGACGTGACCATTAGACGCTTGCGTGAGAAAATAGAAGACA
CTCCAAGTCGTCCAGAGTACATTCTCACACGTCGTGGTGTTGGATACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

92.308

99.574

0.919
  vicR Streptococcus mutans UA159

77.021

100

0.77
  covR Streptococcus salivarius strain HSISS4

44.156

98.298

0.434
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.723

98.298

0.43
  scnR Streptococcus mutans UA159

37.179

99.574

0.37

Multiple sequence alignment