Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NYE79_RS04050 Genome accession   NZ_CP150168
Coordinates   805721..806461 (+) Length   246 a.a.
NCBI ID   WP_070567629.1    Uniprot ID   A0A1E9FZB1
Organism   Streptococcus sp. FSL W8-0197     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 800721..811461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE79_RS04040 (NYE79_04040) - 801545..804073 (+) 2529 WP_070684031.1 MBL fold metallo-hydrolase -
  NYE79_RS04045 (NYE79_04045) - 804120..805598 (-) 1479 WP_000789711.1 oligosaccharide flippase family protein -
  NYE79_RS04050 (NYE79_04050) mecA 805721..806461 (+) 741 WP_070567629.1 adaptor protein MecA Regulator
  NYE79_RS04055 (NYE79_04055) - 806609..807895 (+) 1287 WP_070684027.1 homoserine dehydrogenase -
  NYE79_RS04060 (NYE79_04060) thrB 807897..808766 (+) 870 WP_070684024.1 homoserine kinase -
  NYE79_RS04065 (NYE79_04065) msrB 809027..809965 (+) 939 WP_070684021.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28524.32 Da        Isoelectric Point: 4.1097

>NTDB_id=964605 NYE79_RS04050 WP_070567629.1 805721..806461(+) (mecA) [Streptococcus sp. FSL W8-0197]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETENKKEPYIYYILRFA
SLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=964605 NYE79_RS04050 WP_070567629.1 805721..806461(+) (mecA) [Streptococcus sp. FSL W8-0197]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTCGACGTCTTTGTGACCAAGTCCAAGATT
GACCAAAATTTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCAGATGAATTTCT
CAAAACCTTGGAAAAGAGCATTGCAGATAAGACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACGGAGAATAAGAAAGAACCTTATATCTACTATATCCTACGCTTTGCA
AGCCTTGCTGACTTAGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACATCTGAACTCTATAAGATGAATGGACA
CTATTATTTGACAATCTTAGTCGATGTGGAAAATCATCCAAGTCCATATCCGGCTTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGACGACAGTGACATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATATTGATTAACCACGATGCAGTTCTCGGT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E9FZB1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.574

99.187

0.898
  mecA Streptococcus pneumoniae D39

90.574

99.187

0.898
  mecA Streptococcus pneumoniae R6

90.574

99.187

0.898
  mecA Streptococcus pneumoniae TIGR4

90.164

99.187

0.894
  mecA Streptococcus thermophilus LMD-9

47.222

100

0.484
  mecA Streptococcus mutans UA159

48.361

99.187

0.48
  mecA Streptococcus thermophilus LMG 18311

46.825

100

0.48

Multiple sequence alignment