Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   WJ054_RS05680 Genome accession   NZ_CP149485
Coordinates   1115595..1116269 (-) Length   224 a.a.
NCBI ID   WP_014612304.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain STG643     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1110595..1121269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WJ054_RS05655 (WJ054_05640) - 1110781..1112058 (-) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -
  WJ054_RS05660 (WJ054_05645) - 1112045..1112644 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  WJ054_RS05665 (WJ054_05650) coaA 1112912..1113832 (+) 921 WP_084916836.1 type I pantothenate kinase -
  WJ054_RS05670 (WJ054_05655) rpsT 1113886..1114134 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  WJ054_RS05675 (WJ054_05660) ciaH 1114292..1115602 (-) 1311 WP_014612303.1 cell wall metabolism sensor histidine kinase WalK Regulator
  WJ054_RS05680 (WJ054_05665) ciaR 1115595..1116269 (-) 675 WP_014612304.1 response regulator transcription factor Regulator
  WJ054_RS05685 (WJ054_05670) - 1116473..1119010 (-) 2538 WP_084916834.1 M1 family metallopeptidase -
  WJ054_RS05690 (WJ054_05675) phoU 1119211..1119864 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -
  WJ054_RS05695 (WJ054_05680) pstB 1119942..1120700 (-) 759 WP_003057749.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25592.57 Da        Isoelectric Point: 4.4128

>NTDB_id=959384 WJ054_RS05680 WP_014612304.1 1115595..1116269(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain STG643]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGQGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGRPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=959384 WJ054_RS05680 WP_014612304.1 1115595..1116269(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain STG643]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGTTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACAGGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTTGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACAGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAATGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCGGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTGTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(5-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.163

98.661

0.83
  ciaR Streptococcus pneumoniae D39

84.163

98.661

0.83
  ciaR Streptococcus pneumoniae R6

84.163

98.661

0.83
  ciaR Streptococcus pneumoniae TIGR4

84.163

98.661

0.83
  ciaR Streptococcus mutans UA159

83.71

98.661

0.826
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.326

100

0.388
  vicR Streptococcus mutans UA159

35.443

100

0.375