Detailed information
Bioinformatically predicted
Overview
| Name | comA/nlmT | Type | Regulator |
| Locus tag | WJ054_RS02860 | Genome accession | NZ_CP149485 |
| Coordinates | 537539..539692 (-) | Length | 717 a.a. |
| NCBI ID | WP_084916306.1 | Uniprot ID | - |
| Organism | Streptococcus dysgalactiae subsp. equisimilis strain STG643 | ||
| Function | transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 509109..558518 | 537539..539692 | within | 0 |
Gene organization within MGE regions
Location: 509109..558518
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| WJ054_RS02710 (WJ054_02705) | - | 509208..511616 (+) | 2409 | WP_037590009.1 | DNA translocase FtsK | - |
| WJ054_RS02715 (WJ054_02710) | - | 511685..512038 (-) | 354 | WP_037587264.1 | DUF3397 domain-containing protein | - |
| WJ054_RS02720 (WJ054_02715) | rplK | 512281..512706 (+) | 426 | WP_003049875.1 | 50S ribosomal protein L11 | - |
| WJ054_RS02725 (WJ054_02720) | rplA | 512812..513501 (+) | 690 | WP_003049876.1 | 50S ribosomal protein L1 | - |
| WJ054_RS02730 (WJ054_02725) | - | 513959..514126 (-) | 168 | WP_003054374.1 | hypothetical protein | - |
| WJ054_RS02735 (WJ054_02730) | pyrH | 514394..515122 (+) | 729 | WP_003049878.1 | UMP kinase | - |
| WJ054_RS02740 (WJ054_02735) | frr | 515151..515708 (+) | 558 | WP_003054381.1 | ribosome recycling factor | - |
| WJ054_RS02745 (WJ054_02740) | - | 515817..516674 (+) | 858 | WP_003054345.1 | S1 RNA-binding domain-containing protein | - |
| WJ054_RS02750 (WJ054_02745) | msrA | 516747..517256 (+) | 510 | WP_003054395.1 | peptide-methionine (S)-S-oxide reductase MsrA | - |
| WJ054_RS02755 (WJ054_02750) | - | 517253..517468 (+) | 216 | WP_003054340.1 | YozE family protein | - |
| WJ054_RS02760 (WJ054_02755) | - | 517628..518824 (+) | 1197 | WP_046159274.1 | LysM domain-containing protein | - |
| WJ054_RS02765 (WJ054_02760) | - | 519135..520907 (+) | 1773 | WP_111678971.1 | oleate hydratase | - |
| WJ054_RS02770 (WJ054_02765) | - | 521068..522129 (+) | 1062 | WP_111678972.1 | PhoH family protein | - |
| WJ054_RS02775 (WJ054_02770) | - | 522176..522751 (+) | 576 | WP_003054351.1 | uracil-DNA glycosylase family protein | - |
| WJ054_RS02780 (WJ054_02775) | ybeY | 522910..523407 (+) | 498 | WP_003054373.1 | rRNA maturation RNase YbeY | - |
| WJ054_RS02785 (WJ054_02780) | - | 523388..523795 (+) | 408 | WP_003054389.1 | diacylglycerol kinase family protein | - |
| WJ054_RS02790 (WJ054_02785) | era | 523916..524812 (+) | 897 | WP_002985743.1 | GTPase Era | - |
| WJ054_RS02795 (WJ054_02790) | - | 524833..525309 (+) | 477 | WP_002993018.1 | NUDIX hydrolase | - |
| WJ054_RS02800 (WJ054_02795) | - | 525618..525869 (-) | 252 | WP_080589767.1 | hypothetical protein | - |
| WJ054_RS02805 (WJ054_02800) | - | 526170..526388 (+) | 219 | WP_072135532.1 | LytTR family transcriptional regulator DNA-binding domain-containing protein | - |
| WJ054_RS02810 (WJ054_02805) | - | 526585..528382 (-) | 1798 | Protein_496 | peptide cleavage/export ABC transporter | - |
| WJ054_RS02815 (WJ054_02810) | - | 528680..528907 (+) | 228 | WP_022554332.1 | Blp family class II bacteriocin | - |
| WJ054_RS02820 (WJ054_02815) | - | 528956..529273 (+) | 318 | WP_002994587.1 | hypothetical protein | - |
| WJ054_RS02825 (WJ054_02820) | - | 529393..530477 (+) | 1085 | Protein_499 | IS3 family transposase | - |
| WJ054_RS02830 (WJ054_02825) | - | 530691..532109 (+) | 1419 | WP_406848831.1 | IS1182 family transposase | - |
| WJ054_RS02840 (WJ054_02835) | comE/blpR | 533730..534479 (+) | 750 | WP_030126108.1 | response regulator transcription factor | Regulator |
| WJ054_RS02845 (WJ054_02840) | - | 534480..535814 (+) | 1335 | WP_063631787.1 | sensor histidine kinase | - |
| WJ054_RS02850 (WJ054_02845) | - | 535962..536087 (-) | 126 | WP_011017462.1 | ComC/BlpC family leader-containing pheromone/bacteriocin | - |
| WJ054_RS02855 (WJ054_02850) | - | 536164..537528 (-) | 1365 | WP_084916305.1 | bacteriocin secretion accessory protein | - |
| WJ054_RS02860 (WJ054_02855) | comA/nlmT | 537539..539692 (-) | 2154 | WP_084916306.1 | peptide cleavage/export ABC transporter | Regulator |
| WJ054_RS02865 (WJ054_02860) | - | 539979..540206 (+) | 228 | WP_002992018.1 | Blp family class II bacteriocin | - |
| WJ054_RS02870 (WJ054_02865) | - | 540219..540419 (+) | 201 | WP_003060803.1 | class IIb bacteriocin, lactobin A/cerein 7B family | - |
| WJ054_RS02875 (WJ054_02870) | - | 540713..540907 (+) | 195 | WP_002990768.1 | hypothetical protein | - |
| WJ054_RS02880 (WJ054_02875) | - | 540955..541236 (+) | 282 | WP_011054252.1 | hypothetical protein | - |
| WJ054_RS02885 (WJ054_02880) | - | 541430..541840 (+) | 411 | WP_003061293.1 | hypothetical protein | - |
| WJ054_RS02890 (WJ054_02885) | - | 542087..542334 (+) | 248 | Protein_512 | hypothetical protein | - |
| WJ054_RS02895 (WJ054_02890) | - | 542356..542610 (+) | 255 | WP_014612089.1 | CPBP family intramembrane glutamic endopeptidase | - |
| WJ054_RS02900 (WJ054_02895) | - | 542995..543759 (+) | 765 | WP_003061232.1 | hypothetical protein | - |
| WJ054_RS02905 (WJ054_02900) | - | 543909..544835 (-) | 927 | Protein_515 | hypothetical protein | - |
| WJ054_RS02910 (WJ054_02905) | shp2 | 544920..544988 (-) | 69 | WP_134771781.1 | peptide pheromone SHP2 | - |
| WJ054_RS02915 (WJ054_02910) | rgg2 | 545078..545932 (+) | 855 | Protein_517 | quorum-sensing system transcriptional regulator Rgg2 | - |
| WJ054_RS02920 (WJ054_02915) | mutM | 546114..546941 (+) | 828 | WP_084916308.1 | DNA-formamidopyrimidine glycosylase | - |
| WJ054_RS02925 (WJ054_02920) | coaE | 546920..547531 (+) | 612 | WP_172453883.1 | dephospho-CoA kinase | - |
| WJ054_RS02930 (WJ054_02925) | - | 547899..548600 (+) | 702 | WP_003056868.1 | ATP-binding cassette domain-containing protein | - |
| WJ054_RS02935 (WJ054_02930) | - | 548590..550227 (+) | 1638 | WP_022554345.1 | hypothetical protein | - |
| WJ054_RS02940 (WJ054_02935) | - | 550337..551839 (+) | 1503 | WP_406848832.1 | helicase HerA-like domain-containing protein | - |
| WJ054_RS02945 (WJ054_02940) | - | 552018..553220 (+) | 1203 | WP_080147973.1 | multidrug efflux MFS transporter | - |
| WJ054_RS02950 (WJ054_02945) | rpmG | 553217..553363 (+) | 147 | WP_003047126.1 | 50S ribosomal protein L33 | - |
| WJ054_RS02955 (WJ054_02950) | secG | 553409..553645 (+) | 237 | WP_003047129.1 | preprotein translocase subunit SecG | - |
| WJ054_RS02960 (WJ054_02955) | rnr | 553742..556072 (+) | 2331 | WP_172453884.1 | ribonuclease R | - |
| WJ054_RS02965 (WJ054_02960) | smpB | 556075..556542 (+) | 468 | WP_022554349.1 | SsrA-binding protein SmpB | - |
| WJ054_RS02970 (WJ054_02965) | - | 556721..557077 (+) | 357 | WP_003053910.1 | hypothetical protein | - |
| WJ054_RS02975 (WJ054_02970) | - | 557170..558518 (+) | 1349 | WP_111679041.1 | IS3 family transposase | - |
Sequence
Protein
Download Length: 717 a.a. Molecular weight: 80504.46 Da Isoelectric Point: 7.1728
>NTDB_id=959370 WJ054_RS02860 WP_084916306.1 537539..539692(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis strain STG643]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVIYQNKKNYLIIGDPDSTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVGYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVIYQNKKNYLIIGDPDSTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVGYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS
Nucleotide
Download Length: 2154 bp
>NTDB_id=959370 WJ054_RS02860 WP_084916306.1 537539..539692(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis strain STG643]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGATTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCATCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACTCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTCTTTGCAACACGTCGGACAGGAGAAATCATCTC
ACGTTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTCCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGGCTATCTGGATAAATCCTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACTAAACTGCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAGTTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCACTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGCA
AAATTATTGAAATAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTAGTTAA
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGATTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCATCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACTCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTCTTTGCAACACGTCGGACAGGAGAAATCATCTC
ACGTTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTCCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGGCTATCTGGATAAATCCTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACTAAACTGCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAGTTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCACTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGCA
AAATTATTGAAATAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTAGTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA/nlmT | Streptococcus mutans UA159 |
72.448 |
99.721 |
0.722 |
| comA | Streptococcus mitis NCTC 12261 |
67.227 |
99.582 |
0.669 |
| comA | Streptococcus mitis SK321 |
66.807 |
99.582 |
0.665 |
| comA | Streptococcus pneumoniae Rx1 |
66.807 |
99.582 |
0.665 |
| comA | Streptococcus pneumoniae D39 |
66.807 |
99.582 |
0.665 |
| comA | Streptococcus pneumoniae R6 |
66.807 |
99.582 |
0.665 |
| comA | Streptococcus pneumoniae TIGR4 |
66.527 |
99.582 |
0.662 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
65.738 |
100 |
0.658 |