Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   ACIO08_RS04105 Genome accession   NZ_CP173233
Coordinates   922771..924093 (-) Length   440 a.a.
NCBI ID   WP_410679009.1    Uniprot ID   -
Organism   Avibacterium paragallinarum strain npAP/OH-USA/20230213/S1-2     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 917771..929093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIO08_RS04080 (ACIO08_04080) secM 919315..919626 (-) 312 WP_410679004.1 secA translation cis-regulator SecM -
  ACIO08_RS04085 (ACIO08_04085) - 919732..920037 (+) 306 WP_410679006.1 DciA family protein -
  ACIO08_RS04090 (ACIO08_04090) - 920009..920899 (-) 891 WP_017806825.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  ACIO08_RS04095 (ACIO08_04095) aroB 920905..921993 (-) 1089 WP_410679008.1 3-dehydroquinate synthase -
  ACIO08_RS04100 (ACIO08_04100) aroK 922010..922570 (-) 561 WP_272487554.1 shikimate kinase AroK -
  ACIO08_RS04105 (ACIO08_04105) comE 922771..924093 (-) 1323 WP_410679009.1 type IV pilus secretin PilQ Machinery gene
  ACIO08_RS04110 (ACIO08_04110) - 924102..924461 (-) 360 WP_017806828.1 hypothetical protein -
  ACIO08_RS04115 (ACIO08_04115) - 924461..925009 (-) 549 WP_410679010.1 hypothetical protein -
  ACIO08_RS04120 (ACIO08_04120) - 924975..925487 (-) 513 WP_410679011.1 PilN domain-containing protein -
  ACIO08_RS04125 (ACIO08_04125) comA 925517..926284 (-) 768 WP_410679013.1 hypothetical protein Machinery gene
  ACIO08_RS04130 (ACIO08_04130) - 926443..928992 (+) 2550 WP_410679014.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 48592.56 Da        Isoelectric Point: 6.1204

>NTDB_id=957652 ACIO08_RS04105 WP_410679009.1 922771..924093(-) (comE) [Avibacterium paragallinarum strain npAP/OH-USA/20230213/S1-2]
MKLPNIIKNILLFFLILSYPFRQVNASDENNTFSVHLKQAPLVDTVQYLAGYQKINLVIDDELSGSISLQLQNTTLLQLL
KSIAEIKHLRFWENNGIYYLSQSQATNQENVVLNSSTEIATSADMLITSIKLHYAKASEVMKALTSGNGSLLTANGSISF
DERNNLLIIQDEAKKIKQIRKLVADMDKPIQQIIIEARIVTISDESLKELGVRWGIFSPSDISHSVSGSLNANGFSNITD
NLNINFATSSNPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVNNGKNDTQSIE
FREAVLGLEVTPHLLKHNGILLDLVVSQNAPGGRVSYGENEVISIDKQEINTQVFAQDGETIVLGGIFHDTITKALDKVP
ILGDIPGVKRLFSKEVERHQKRELVIFVTPRLIRSGTVEE

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=957652 ACIO08_RS04105 WP_410679009.1 922771..924093(-) (comE) [Avibacterium paragallinarum strain npAP/OH-USA/20230213/S1-2]
ATGAAGTTACCAAATATAATAAAGAATATTCTTTTATTTTTTCTTATTCTATCCTATCCATTTAGACAGGTTAATGCAAG
TGACGAAAATAATACATTCTCTGTTCATTTAAAGCAAGCTCCATTAGTAGATACTGTACAATATTTAGCTGGGTATCAAA
AAATCAATTTAGTCATAGATGATGAATTGTCTGGTTCAATATCTTTGCAATTGCAAAATACAACATTACTTCAATTATTA
AAATCTATCGCTGAAATAAAACATTTGCGGTTTTGGGAAAATAATGGGATATATTATTTAAGTCAGTCGCAAGCAACTAA
TCAAGAAAATGTAGTGTTAAATTCATCAACAGAAATAGCAACATCAGCAGATATGTTAATAACTTCAATAAAGTTGCACT
ATGCCAAAGCATCCGAGGTAATGAAAGCCCTCACTTCAGGGAATGGCTCTTTATTAACAGCAAATGGAAGTATAAGTTTT
GATGAACGCAATAATTTACTCATTATCCAAGATGAAGCTAAAAAAATAAAACAAATTAGGAAATTGGTAGCGGATATGGA
TAAACCCATTCAGCAAATTATTATTGAAGCTCGTATTGTCACAATTAGCGATGAAAGTTTAAAAGAATTGGGCGTTAGAT
GGGGAATTTTTTCTCCCTCAGATATAAGCCATAGCGTTTCTGGAAGTTTAAATGCAAATGGATTCTCAAATATTACGGAT
AATCTAAATATTAATTTTGCGACGAGTTCAAATCCTGCAGGTTCGGTAGCTTTGCAAGTAGCTAAAATTAATGGAAGGTT
ATTAGATTTAGAGTTGACAGCATTAGAAAGAGAAAATAACGTTGAAATTATTGCGAGTCCACGATTATTGACCACAAATA
AGAAAAGTGCAAGTATCAAGCAAGGTACAGAAATCCCCTATGTAGTGAATAATGGAAAAAATGATACGCAGTCTATTGAA
TTCCGAGAAGCTGTACTTGGGCTTGAAGTTACACCTCATTTATTAAAGCATAACGGTATTTTACTTGATCTTGTTGTTAG
CCAGAATGCACCTGGAGGACGAGTATCTTATGGAGAAAATGAGGTGATTTCTATTGATAAACAGGAAATTAATACGCAAG
TCTTTGCACAAGACGGCGAAACGATTGTATTGGGCGGAATTTTCCACGATACGATTACTAAAGCACTTGATAAAGTACCA
ATTTTAGGAGACATACCTGGAGTAAAAAGGCTATTTAGTAAGGAGGTCGAGAGACATCAAAAGAGGGAACTCGTTATTTT
TGTTACACCACGCTTAATTCGTAGTGGTACAGTAGAGGAATGA

Domains

Predicted by InterProScan.

Bacterial type II and III secretion system protein (Secretin)

(274-434)

Bacterial type II/III secretion system short domain (Secretin_N)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

64.789

96.818

0.627
  comE Haemophilus influenzae 86-028NP

66.102

93.864

0.62
  comE Glaesserella parasuis strain SC1401

49.649

97.045

0.482
  pilQ Vibrio campbellii strain DS40M4

40

96.591

0.386
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

40.288

94.773

0.382
  pilQ Vibrio cholerae strain A1552

40.288

94.773

0.382