Detailed information NTG0957052

Bioinformatically predicted

Overview

• Name: pknB
• Type: Regulator
• Locus tag: ACIQTD_RS10090
• Genome accession: NZ_CP173185
• Coordinates: 2097440..2099323 (-)
• Length: 627 a.a.
• NCBI ID: WP_017864971.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain MGEL24009
• Function: modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology) Competence regulation

Genomic Context

Location: 2092440..2104323

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIQTD_RS10060	-	2092841..2093521 (-)	681	WP_017864968.1	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	-
ACIQTD_RS10065	macP	2093554..2093832 (-)	279	WP_003130796.1	cell wall synthase accessory phosphoprotein MacP	-
ACIQTD_RS10070	-	2093825..2094409 (-)	585	WP_012898439.1	NUDIX hydrolase	-
ACIQTD_RS10075	glmU	2094514..2095890 (-)	1377	WP_017864970.1	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	-
ACIQTD_RS10080	proC	2096118..2096906 (+)	789	WP_012898440.1	pyrroline-5-carboxylate reductase	-
ACIQTD_RS10085	rpsO	2096985..2097254 (-)	270	WP_015427039.1	30S ribosomal protein S15	-
ACIQTD_RS10090	pknB	2097440..2099323 (-)	1884	WP_017864971.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
ACIQTD_RS10095	-	2099323..2100099 (-)	777	WP_003130802.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
ACIQTD_RS10100	rsmB	2100179..2101453 (-)	1275	WP_404399159.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
ACIQTD_RS10105	-	2101652..2102158 (-)	507	WP_012898444.1	Asp23/Gls24 family envelope stress response protein	-
ACIQTD_RS10110	-	2102179..2102367 (-)	189	WP_012898445.1	DUF2273 domain-containing protein	-
ACIQTD_RS10115	amaP	2102378..2102938 (-)	561	WP_010906186.1	alkaline shock response membrane anchor protein AmaP	-
ACIQTD_RS10120	-	2102966..2103208 (-)	243	WP_003131476.1	GlsB/YeaQ/YmgE family stress response membrane protein	-

Sequence

Protein

• Length: 627 a.a.
• Molecular weight: 67859.95 Da
• Isoelectric Point: 4.7783

>NTDB_id=957052 ACIQTD_RS10090 WP_017864971.1 2097440..2099323(-) (pknB) [Lactococcus lactis subsp. lactis strain MGEL24009]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEDNDSQTD
EKAASSEVGNKNKKSKKGLIIGLIILLLVVGGATLAWVVSTPTNVKIPNVTNSTLSQAKSKIKDAKLKVGTVHKQQSSTI
AEGKVIKTDPTSGTTVRSNSSVDIYVSTGNEDIIKMKDFVGEKIDEAMATLLKDYGIDESQVTQTSVPSDSYPAGTIIKQ
SPKKGSSFDTKGSEKITFEVSSGKQVEVPDYKPNGQYMTYSQYQAALKAAGFTNITLDPQATTNQQADGYVYSVYPNVGT
SVDPTQEIVVTYSVYTAPSSSSTTSESTTTSETSSSTTSSTSSSTTSQPSTDNNNSSKEGSITSSSS

Nucleotide

• Length: 1884 bp

>NTDB_id=957052 ACIQTD_RS10090 WP_017864971.1 2097440..2099323(-) (pknB) [Lactococcus lactis subsp. lactis strain MGEL24009]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGTGGCGGAATGGCGAACGTTTA
TCAAGGTGAAGATACTTTTCTTGGTGACCGCTTAGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAACGATGATATCG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGATGTTGGT
GAATTTGAAAGTCAACAATACATTGTCATGGAATTTGTTGACGGCATGACACTTAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACTGAAATTTTATCAGCAATGGACATGGCCCATTCACATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGTAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAAGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCGGTTCATTATTTATCACCAGAGCAAGCGCGTGGTTC
AAATGCAACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAACTTTTAACAGGTCAAATTCCATTTGATG
GAGATTCTGCAGTTGCTATCGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATCAATCTCAATCCAGAAGTTCCG
CAAGCTTTGGAAAATGTTGTCATTAAAGCTACAGCGAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAC
TGATGTGGCAACTTCAACGAGTCTTGACCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGATCATGATGAAACAAAAA
TTATGCCTGCCAATCTAATTAATCCTTATGACACCAAGCCTCTGATTGATAAAAAAGAAGATAATGATTCACAAACAGAT
GAAAAAGCTGCAAGCTCAGAAGTAGGAAATAAAAACAAAAAATCTAAAAAAGGCTTGATTATTGGTCTTATTATCCTTCT
TTTAGTTGTTGGCGGTGCTACTTTGGCTTGGGTTGTCTCAACACCAACTAATGTTAAGATACCTAATGTGACAAACTCGA
CACTTAGCCAAGCAAAAAGCAAAATTAAAGATGCAAAACTTAAAGTGGGAACAGTTCATAAACAACAAAGTTCAACGATT
GCTGAAGGAAAAGTTATCAAGACTGATCCAACTAGTGGAACAACCGTGAGATCTAATAGCTCCGTTGATATCTATGTTTC
TACGGGAAATGAAGATATCATCAAAATGAAGGACTTTGTCGGTGAAAAGATTGATGAGGCGATGGCAACATTACTTAAGG
ATTATGGTATTGATGAAAGCCAAGTCACTCAAACTTCCGTTCCTAGTGATTCTTACCCAGCAGGTACAATCATTAAACAA
AGCCCTAAAAAAGGTTCTAGTTTTGATACCAAAGGGAGTGAAAAAATTACCTTTGAAGTTTCAAGTGGAAAACAAGTTGA
AGTTCCGGATTATAAACCGAACGGTCAATATATGACTTATTCACAGTATCAAGCTGCCTTAAAAGCTGCAGGATTCACTA
ATATTACACTAGACCCTCAAGCAACAACGAATCAACAAGCTGATGGTTATGTTTACTCAGTGTATCCAAATGTAGGGACA
TCTGTTGATCCAACTCAAGAAATTGTAGTCACTTATAGCGTTTATACTGCTCCAAGTTCAAGTTCAACAACTTCTGAATC
AACTACGACGTCTGAAACTTCATCAAGTACAACTTCAAGTACTTCAAGCTCTACAACAAGTCAGCCGTCAACAGATAACA
ACAATAGCAGCAAAGAAGGTTCAATAACTTCATCAAGTAGTTAA

Domains

Predicted by InterProScan.

• PASTA domain (PASTA) (365-428)

• PASTA domain (PASTA) (506-573)

• PASTA domain (PASTA) (434-501)

• Protein kinase domain (Pkinase) (12-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pknB	Streptococcus mutans UA159	49.265	86.762	0.427
stkP/pknB	Streptococcus salivarius strain HSISS4	51.445	82.775	0.426
stkP	Streptococcus pneumoniae TIGR4	48.024	80.702	0.388
stkP	Streptococcus pneumoniae D39	47.826	80.702	0.386
stkP	Streptococcus pneumoniae R6	47.826	80.702	0.386
stkP	Streptococcus pneumoniae Rx1	47.628	80.702	0.384