Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   WDK84_RS13655 Genome accession   NZ_CP148055
Coordinates   2606987..2608285 (+) Length   432 a.a.
NCBI ID   WP_083578710.1    Uniprot ID   -
Organism   Enterococcus faecalis strain J-5     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2601987..2613285
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WDK84_RS13650 (WDK84_13660) rlmH 2606107..2606586 (-) 480 WP_002355021.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  WDK84_RS13655 (WDK84_13665) htrA 2606987..2608285 (+) 1299 WP_083578710.1 trypsin-like peptidase domain-containing protein Regulator
  WDK84_RS13660 (WDK84_13670) ytpR 2608332..2608952 (-) 621 WP_002407823.1 YtpR family tRNA-binding protein -
  WDK84_RS13665 (WDK84_13675) - 2609056..2609880 (-) 825 WP_002385250.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
  WDK84_RS13670 (WDK84_13680) - 2609864..2610634 (-) 771 WP_338842116.1 PTS sugar transporter subunit IIC -
  WDK84_RS13675 (WDK84_13685) - 2610656..2611129 (-) 474 WP_002359087.1 PTS sugar transporter subunit IIB -
  WDK84_RS13680 (WDK84_13690) - 2611132..2611875 (-) 744 WP_002359086.1 BtpA/SgcQ family protein -
  WDK84_RS13685 (WDK84_13695) - 2611887..2612297 (-) 411 WP_002359084.1 PTS sugar transporter subunit IIA -
  WDK84_RS13690 (WDK84_13700) - 2612312..2613043 (-) 732 WP_002359083.1 GntR family transcriptional regulator -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 44845.98 Da        Isoelectric Point: 4.9968

>NTDB_id=950263 WDK84_RS13655 WP_083578710.1 2606987..2608285(+) (htrA) [Enterococcus faecalis strain J-5]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSVINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRAVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=950263 WDK84_RS13655 WP_083578710.1 2606987..2608285(+) (htrA) [Enterococcus faecalis strain J-5]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCCCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACATCCACTAATCACGGCGACACAAAAGTCAGCAATGTAAGTTACAATGTGTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCGCAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGAAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCAATTG
GTTCCCCTCTAGGCTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCCATCAATCCAGGAAACTCTGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGCTGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACCATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(319-416)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

Peptidase family M50 (Peptidase_M50)

(9-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

53.171

94.907

0.505
  htrA Streptococcus mutans UA159

58.63

84.491

0.495
  htrA Streptococcus mitis NCTC 12261

55.135

85.648

0.472
  htrA Streptococcus pneumoniae TIGR4

55.807

81.713

0.456
  htrA Streptococcus pneumoniae Rx1

55.807

81.713

0.456
  htrA Streptococcus pneumoniae D39

55.807

81.713

0.456
  htrA Streptococcus pneumoniae R6

55.807

81.713

0.456