NTDB

Overview

Name	comA	Type	Regulator
Locus tag	AAA982_RS05050	Genome accession	NZ_AP028601
Coordinates	978459..979070 (+)	Length	203 a.a.
NCBI ID	WP_061642211.1	Uniprot ID	-
Organism	Streptococcus pneumoniae strain PF1
Function	processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 973459..984070

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA982_RS05025 (TKY113292_09830)	-	974060..975142 (+)	1083	Protein_991	alpha amylase N-terminal ig-like domain-containing protein	-
AAA982_RS05030	-	975136..976124 (+)	989	Protein_992	relaxase/mobilization nuclease domain-containing protein	-
AAA982_RS05035	-	976293..976355 (+)	63	WP_133457516.1	SHP2/SHP3 family peptide pheromone	-
AAA982_RS05040 (TKY113292_09870)	-	976436..976984 (+)	549	WP_000059558.1	lanthionine synthetase LanC family protein	-
AAA982_RS05045 (TKY113292_09880)	-	976977..978290 (+)	1314	WP_130894593.1	cysteine peptidase family C39 domain-containing protein	-
AAA982_RS05050 (TKY113292_09890)	comA	978459..979070 (+)	612	WP_061642211.1	ATP-binding cassette domain-containing protein	Regulator
AAA982_RS05055 (TKY113292_09900)	-	979113..979283 (+)	171	WP_000757486.1	hypothetical protein	-
AAA982_RS05060 (TKY113292_09910)	-	979317..980045 (+)	729	WP_001018881.1	ATP-binding cassette domain-containing protein	-
AAA982_RS05065 (TKY113292_09920)	-	980038..980775 (+)	738	WP_000593057.1	ABC transporter permease	-
AAA982_RS05070 (TKY113292_09930)	-	980788..981498 (+)	711	WP_000771192.1	hypothetical protein	-
AAA982_RS05075 (TKY113292_09940)	-	982046..982267 (+)	222	WP_000286245.1	helix-turn-helix transcriptional regulator	-
AAA982_RS05080	-	982715..983017 (+)	303	Protein_1002	transposase family protein	-

Sequence

Protein

Download Length: 203 a.a. Molecular weight: 22222.80 Da Isoelectric Point: 7.8446

                                >NTDB_id=94997 AAA982_RS05050 WP_061642211.1 978459..979070(+) (comA) [Streptococcus pneumoniae strain PF1]

MTIEPGQRIALVGQSGSGKSTLSKILSGLYKIDTGKILFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKNEV

TSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQS

QGCTQIIIAHRLSTIKDADIIFVMKGGKIVESGNHKYLMDLGG

Nucleotide

Download Length: 612 bp

                                >NTDB_id=94997 AAA982_RS05050 WP_061642211.1 978459..979070(+) (comA) [Streptococcus pneumoniae strain PF1]

TTGACTATTGAGCCAGGACAGAGAATTGCACTAGTCGGTCAATCGGGGTCAGGAAAAAGTACGTTATCAAAAATACTATC

AGGATTATATAAGATTGATACAGGAAAAATTTTATTTGATGGTGTAAATATTAATCAAATAGATAAAAAAATATTAAGTC

AAAATTTAGGAGTAGTTCCACAGGATTCATTTTTATTGAACCGAAGTATTCTTGATAATATAACTTTAAAGAACGAAGTT

ACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAATTTAATAC

TATCATCTCAGAGATGGGGTCAAATATTTCAGGTGGGCAAAGGCAACGGATAGCACTGGCACGTGCATTAATAAATAATC

CTAGTATTGTAATTTTAGATGAAGCAACTAGTGCATTAGACACTATTAATGAGGAAAGAATAACAAAGTATATACAAAGT

CAGGGTTGTACTCAAATAATTATAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTTTTGTAATGAAAGGTGG

TAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGGATCTTGGTGGATAG

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(1-144)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comA	Streptococcus mitis NCTC 12261	44.39	100	0.448
comA	Streptococcus mitis SK321	43.902	100	0.443
comA	Streptococcus gordonii str. Challis substr. CH1	42.995	100	0.438
comA	Streptococcus pneumoniae R6	42.927	100	0.433
comA	Streptococcus pneumoniae Rx1	42.927	100	0.433
comA	Streptococcus pneumoniae D39	42.927	100	0.433
comA	Streptococcus pneumoniae TIGR4	41.951	100	0.424
comA/nlmT	Streptococcus mutans UA159	42.079	99.507	0.419
rcrQ	Streptococcus mutans UA159	37.438	100	0.374

Detailed information NTG0094997