Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   WAE38_RS03735 Genome accession   NZ_CP147984
Coordinates   678279..679541 (+) Length   420 a.a.
NCBI ID   WP_160404856.1    Uniprot ID   A0AAX1M6L4
Organism   Glaesserella parasuis strain H16SD2BY4     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 673279..684541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WAE38_RS03710 (WAE38_03710) - 673473..676028 (-) 2556 WP_062923927.1 penicillin-binding protein 1A -
  WAE38_RS03715 (WAE38_03715) comA 676182..676859 (+) 678 WP_021113429.1 hypothetical protein Machinery gene
  WAE38_RS03720 (WAE38_03720) comB 676835..677356 (+) 522 WP_160404857.1 hypothetical protein Machinery gene
  WAE38_RS03725 (WAE38_03725) comC 677353..677883 (+) 531 WP_021115650.1 hypothetical protein Machinery gene
  WAE38_RS03730 (WAE38_03730) comD 677928..678269 (+) 342 WP_234799212.1 hypothetical protein Machinery gene
  WAE38_RS03735 (WAE38_03735) comE 678279..679541 (+) 1263 WP_160404856.1 type IV pilus secretin PilQ Machinery gene
  WAE38_RS03740 (WAE38_03740) nusB 679620..680033 (+) 414 WP_021116599.1 transcription antitermination factor NusB -
  WAE38_RS03745 (WAE38_03745) thiL 680042..681010 (+) 969 WP_160404852.1 thiamine-phosphate kinase -
  WAE38_RS03750 (WAE38_03750) - 681013..681483 (+) 471 WP_005712497.1 phosphatidylglycerophosphatase A -
  WAE38_RS03755 (WAE38_03755) - 681485..682114 (+) 630 WP_160404850.1 LysE family transporter -
  WAE38_RS03760 (WAE38_03760) trxA 682411..682725 (+) 315 WP_015940165.1 thioredoxin -
  WAE38_RS03765 (WAE38_03765) - 683270..683917 (+) 648 WP_202115139.1 transposase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 47038.92 Da        Isoelectric Point: 7.7191

>NTDB_id=949832 WAE38_RS03735 WP_160404856.1 678279..679541(+) (comE) [Glaesserella parasuis strain H16SD2BY4]
MRYLFLLFFATFPVLANQQISLSIRNAPTAEIISYLAEETGKNITISDEIKDTKNFRVEKSHFDEILNSLIKTHQLNLKK
ENGIYYIHQAQEHKQHTTAQLVNALPKLITKTIKLHYSKASEVIESLTKGQGNLLSESGYLHFDDRSNSIIVKDSAASVK
NFTQLIESLDKPTEQIAIEARIVTISSEHLQQLGVRWGLFSPNENHYKLAGNLEGNGLTTNNLNVNFPVNPSASVALQIA
AINGRVLDLELTALESENNIEIIASPRLLTTDKKPASIKQGTEIPYAMYSKKEEITDIEFREAVLGLEVTPHISKQNQIL
LDLAISQNSPNNQINNTMVTIDKQEIKTQVLAKHGETIVLGGIFQHLIAKGEDKVPLLGSIPVIKRLFSQNRDRISKREL
VIFVTPYIVKSEKMGAEKQK

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=949832 WAE38_RS03735 WP_160404856.1 678279..679541(+) (comE) [Glaesserella parasuis strain H16SD2BY4]
ATGCGTTATTTATTCCTGCTATTCTTTGCTACTTTTCCTGTATTAGCAAACCAACAAATTTCACTTTCGATAAGAAATGC
CCCAACGGCAGAGATTATTAGTTATTTGGCGGAGGAAACGGGAAAGAATATTACAATTTCGGATGAAATTAAAGATACAA
AAAATTTCAGAGTAGAAAAAAGCCATTTTGATGAGATATTAAATAGTTTAATCAAAACACATCAATTAAATTTAAAAAAA
GAAAATGGCATTTACTATATTCATCAAGCCCAAGAACATAAACAACATACTACGGCACAATTAGTTAATGCTCTGCCTAA
ATTAATCACCAAAACAATCAAGTTACACTATTCCAAAGCCTCTGAAGTTATAGAGTCTTTAACAAAAGGGCAAGGCAATT
TACTATCAGAAAGTGGTTATCTTCACTTTGATGATCGCAGTAATAGCATTATCGTCAAAGACAGTGCCGCCTCAGTTAAA
AACTTTACTCAACTTATCGAAAGCCTAGATAAACCAACGGAACAAATTGCAATTGAAGCCCGAATTGTCACTATCAGCAG
TGAACATTTACAACAACTTGGCGTGCGTTGGGGCTTATTTTCCCCTAACGAAAATCACTACAAATTGGCAGGCAATTTAG
AAGGCAACGGATTAACTACCAACAACTTAAACGTAAATTTTCCAGTAAATCCGTCCGCTTCTGTTGCCTTACAAATTGCT
GCAATCAACGGTCGTGTACTTGATTTAGAACTTACTGCATTAGAAAGCGAAAATAACATAGAGATCATTGCAAGCCCTCG
CTTACTCACAACAGATAAAAAACCAGCGAGTATCAAACAAGGTACAGAAATTCCTTATGCAATGTACAGTAAGAAAGAGG
AAATCACCGATATTGAATTTCGTGAAGCCGTTTTGGGGTTAGAGGTCACGCCACATATTTCTAAACAAAATCAGATTTTG
TTAGACCTCGCTATCAGCCAAAATTCGCCCAATAACCAAATAAATAATACAATGGTGACAATTGATAAACAGGAAATCAA
AACGCAAGTTCTAGCTAAACACGGTGAAACCATCGTATTAGGCGGTATTTTTCAACATCTGATCGCCAAAGGCGAAGATA
AAGTACCGCTGTTAGGCAGTATCCCCGTGATTAAACGCTTATTTAGCCAAAATCGAGATAGAATCTCTAAACGAGAATTA
GTGATTTTTGTTACGCCTTATATTGTAAAATCTGAAAAAATGGGAGCGGAAAAGCAGAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(253-410)

Bacterial type II/III secretion system short domain (Secretin_N)

(110-175)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

98.571

100

0.986
  comE Haemophilus influenzae Rd KW20

53.412

100

0.54
  comE Haemophilus influenzae 86-028NP

52.471

100

0.531
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

38.164

98.571

0.376
  pilQ Vibrio cholerae strain A1552

38.164

98.571

0.376
  pilQ Vibrio campbellii strain DS40M4

36.493

100

0.367