Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   V4331_RS09440 Genome accession   NZ_CP146743
Coordinates   1892880..1894097 (+) Length   405 a.a.
NCBI ID   WP_017369969.1    Uniprot ID   A0A9Q9D6R4
Organism   Lactococcus formosensis subsp. formosensis strain L5     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1887880..1899097
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V4331_RS09410 (V4331_09415) eeP 1887895..1889142 (-) 1248 WP_341784136.1 RIP metalloprotease RseP Regulator
  V4331_RS09415 (V4331_09420) - 1889319..1890113 (-) 795 WP_017369964.1 phosphatidate cytidylyltransferase -
  V4331_RS09420 (V4331_09425) - 1890110..1890847 (-) 738 WP_096368979.1 isoprenyl transferase -
  V4331_RS09425 (V4331_09430) yajC 1891046..1891378 (-) 333 WP_017369966.1 preprotein translocase subunit YajC -
  V4331_RS09430 (V4331_09435) - 1891453..1892100 (-) 648 WP_341784137.1 DNA alkylation repair protein -
  V4331_RS09435 (V4331_09440) rlmH 1892097..1892576 (-) 480 WP_341784138.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  V4331_RS09440 (V4331_09445) htrA 1892880..1894097 (+) 1218 WP_017369969.1 S1C family serine protease Regulator
  V4331_RS09445 (V4331_09450) - 1894194..1895192 (+) 999 WP_096368976.1 glycosyltransferase family 4 protein -
  V4331_RS09450 (V4331_09455) - 1895205..1896539 (+) 1335 WP_165712757.1 glycosyltransferase family 4 protein -
  V4331_RS09455 (V4331_09460) - 1896590..1896814 (+) 225 WP_017369972.1 YkuJ family protein -
  V4331_RS09460 (V4331_09465) - 1896843..1897892 (-) 1050 WP_017369973.1 BMP family protein -
  V4331_RS09465 (V4331_09470) - 1898051..1898800 (-) 750 WP_096368974.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41850.60 Da        Isoelectric Point: 4.6948

>NTDB_id=944026 V4331_RS09440 WP_017369969.1 1892880..1894097(+) (htrA) [Lactococcus formosensis subsp. formosensis strain L5]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNESNSPQLSGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVQETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSSSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
DVTNGVAVAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATTNIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=944026 V4331_RS09440 WP_017369969.1 1892880..1894097(+) (htrA) [Lactococcus formosensis subsp. formosensis strain L5]
ATGGCAAAAAAAAATATCGCCTCATTACTTATTACGGGCGTAGCCGGAGGTGCTATCGCTCTTGGGGGTAGTGCTATCTA
CCAAAATATGACTAACACGCCGTCATCTAATAATACTTCGGACAATTCTGTAAGTACAGTTAACGTACAAGTCAATACAG
ATACAACCAAAGCAATCAAGAAAATTTCAAACACTGTTGTTTCCGTACTTAATTACCAAAAATCGTCTTCAAGCAACGAC
TTTGAAAAGATTTTCGGCGGAGGCGACACAAGCAGCAATGAGAGTAACTCACCACAGCTATCTGGAGAAGGTTCTGGGGT
TATCTATAAAAAGGACGGCAATACCGCATACATCGTAACCAACTATCACGTTATTGAAGGTGCGTCTTCCTTAGAAGTTC
TCATGGCTGGTGGTCAAAAAGTAACTGCCGAAGTTGTTGGTTCCGATGCTTATTCGGATTTAGCTGTCCTCAAAATTGAT
GCCAAGTATGTCCAAGAAACCGCAACGTTCGGCAACTCTGACAAACTTACTGTTGGTGAACCTGCTATCGCCGTTGGTTC
TCCTCTTGGAAGTGAGTATGCTAACTCAGCAACAGAAGGTATTGTTTCTAGTCTTAATCGCAATGTTACATTGCAAAACA
GCCAAGGCCAAACCATTAATGTTAATGCTATTCAAACAGATGCAGCAATAAACCCCGGGAACTCTGGCGGTGCACTCATC
AATATTCAAGGACAAGTCATCGGGATCACCTCAAGTAAAATTACCTCAACACCAAGTGGAACAAGCAGCAGTGGTGTCTC
TGTAGAAGGTATGGGGTTTGCGATTCCAGCCAATGATGTCGTCAATATTATCAATAAATTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTGGGTGTGCAAATGGTTAACCTATCAAGTCTTTCACAAAATATGTTGGCTTCACTTAACCTTCCTGAA
GACGTGACTAATGGTGTTGCTGTCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGCGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGTGTTAACCTTCAAAGCACACTTTATAAATCTTCAATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAAGCTACTACAAATATCAAGTTAGATAAAACAAGTAGTGATATCAAT
TTTGACAAGCAAAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-392)

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

Peptidase family M50 (Peptidase_M50)

(266-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.878

93.333

0.531
  htrA Streptococcus mitis NCTC 12261

53.634

98.519

0.528
  htrA Streptococcus pneumoniae Rx1

53.383

98.519

0.526
  htrA Streptococcus pneumoniae D39

53.383

98.519

0.526
  htrA Streptococcus pneumoniae R6

53.383

98.519

0.526
  htrA Streptococcus pneumoniae TIGR4

53.383

98.519

0.526
  htrA Streptococcus gordonii str. Challis substr. CH1

54.22

96.543

0.523