Detailed information NTG0943975

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: V7A37_RS07805
• Genome accession: NZ_CP146741
• Coordinates: 1562054..1564201 (+)
• Length: 715 a.a.
• NCBI ID: WP_153925280.1
• Uniprot ID: -
• Organism: Lactococcus petauri strain L6
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1546767..1567555	1562054..1564201	within	0

Gene organization within MGE regions

Location: 1546767..1567555

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V7A37_RS07715 (V7A37_07715)	-	1546767..1547549 (-)	783	WP_165712995.1	hypothetical protein	-
V7A37_RS07720 (V7A37_07720)	-	1547850..1548143 (-)	294	WP_160214574.1	helix-turn-helix transcriptional regulator	-
V7A37_RS07725 (V7A37_07725)	-	1548970..1549401 (-)	432	WP_160214575.1	hypothetical protein	-
V7A37_RS07730 (V7A37_07730)	-	1549558..1550238 (+)	681	WP_013646119.1	IS6-like element IS1216 family transposase	-
V7A37_RS07735 (V7A37_07735)	-	1550462..1550854 (-)	393	WP_165719078.1	hypothetical protein	-
V7A37_RS07740 (V7A37_07740)	-	1550869..1552758 (-)	1890	WP_017369570.1	heavy metal translocating P-type ATPase	-
V7A37_RS07745 (V7A37_07745)	-	1552849..1553628 (+)	780	WP_017369569.1	MerR family DNA-binding transcriptional regulator	-
V7A37_RS07750 (V7A37_07750)	-	1553689..1554369 (-)	681	WP_017370594.1	IS6-like element ISLgar4 family transposase	-
V7A37_RS07755 (V7A37_07755)	-	1554445..1554576 (-)	132	Protein_1534	IS6 family transposase	-
V7A37_RS07760 (V7A37_07760)	-	1554710..1555006 (-)	297	WP_165719077.1	BRCT domain-containing protein	-
V7A37_RS07765 (V7A37_07765)	-	1555200..1555772 (+)	573	WP_040087898.1	DUF805 domain-containing protein	-
V7A37_RS07770 (V7A37_07770)	-	1556113..1556562 (+)	450	WP_035002325.1	hypothetical protein	-
V7A37_RS07775 (V7A37_07775)	-	1556576..1559230 (+)	2655	WP_165719076.1	C47 family peptidase	-
V7A37_RS07780 (V7A37_07780)	-	1559957..1560244 (+)	288	WP_035002334.1	hypothetical protein	-
V7A37_RS07785 (V7A37_07785)	-	1560262..1560546 (+)	285	WP_035002336.1	hypothetical protein	-
V7A37_RS07790 (V7A37_07790)	-	1561082..1561267 (+)	186	WP_165719075.1	bacteriocin	-
V7A37_RS07795 (V7A37_07795)	-	1561313..1561612 (+)	300	WP_153925273.1	hypothetical protein	-
V7A37_RS07800 (V7A37_07800)	-	1561680..1561946 (+)	267	WP_153925277.1	bacteriocin immunity protein	-
V7A37_RS07805 (V7A37_07805)	comA	1562054..1564201 (+)	2148	WP_153925280.1	peptide cleavage/export ABC transporter	Regulator
V7A37_RS07810 (V7A37_07810)	-	1564211..1565638 (+)	1428	WP_153925283.1	bacteriocin secretion accessory protein	-
V7A37_RS07820 (V7A37_07820)	-	1566095..1566544 (-)	450	WP_242520602.1	hypothetical protein	-
V7A37_RS07825 (V7A37_07825)	-	1566618..1566809 (-)	192	WP_255566820.1	tyrosine-type recombinase/integrase	-
V7A37_RS07830 (V7A37_07830)	-	1566755..1567555 (-)	801	WP_255566821.1	tyrosine-type recombinase/integrase	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80734.32 Da
• Isoelectric Point: 8.5587

>NTDB_id=943975 V7A37_RS07805 WP_153925280.1 1562054..1564201(+) (comA) [Lactococcus petauri strain L6]
MRFKKKYYTSQIDERDCGCAALSMVLKAYGTEQSLASLRLLAGTTIEGTSALGIKKAAEHLKFSVQAFRADSTLFDTKKL
PCPFIIHVVKEKKYPHYYVVKYSNKKHIIIADPDPTVKIRKMTWDQFYSEWTGVTLFIAPQPSYKPVKEKSESLFSFIPL
IAKQKLLVCQIIIASLLVTLINIIGSYYLQNIIDEYVPNALMKTLGIVSLGLMATYFIQQILNFAQTFLLTILGQRLAID
VILSYIRHIFQLPMSFFSTRRTGEITSRFSDANSIIDALASAILSLFLDVTIVILTGLVLGLQNMSLFFLVLFSIPLYVL
IIFIFIPLFEKQNNEVMQANSILNSSIIEDINGIETIKSLGSEEIRYQKIDREFADYMKKSFTRQKSEAFQTALKSGLQL
VLNVLILWYGATLVVSQKITLGQLITFNVLLSYFMNPLSNIINLQTKLQSAKVANHRLNEVYLVDSEFDTKTDEIILSNF
EMQLIGISYHYGFGRDILSNISLNIKENEKLTIVGMSGSGKSTLVKLLVNFFEPTQGTIILGGIDIKQMDKHQLRRIVSY
LPQHPYIFTGTVLDNLTLGVSEDISQEEIFQAVEAAEIRSDIEQLQLGYQTELSSDATTLSGGQKQRIALARTLLSPAKI
LIFDEATSNLDVITEKKILKNLFKLDKTIIFIAHRLSIAEKSDRIVVIDQGKIMEEGSHLELLSKNGFYAQLYNQ

Nucleotide

• Length: 2148 bp

>NTDB_id=943975 V7A37_RS07805 WP_153925280.1 1562054..1564201(+) (comA) [Lactococcus petauri strain L6]
ATGCGTTTTAAAAAGAAATATTATACTTCACAAATAGATGAAAGAGATTGTGGGTGTGCTGCCCTTTCCATGGTTTTAAA
AGCTTATGGTACAGAACAATCTCTTGCTTCATTACGTTTACTTGCTGGTACAACGATAGAAGGTACCTCTGCTCTAGGTA
TTAAAAAAGCCGCAGAACATTTGAAATTCAGCGTTCAAGCCTTTCGTGCAGATTCAACTCTATTTGATACAAAAAAACTT
CCTTGTCCATTTATCATTCATGTGGTTAAAGAAAAGAAATATCCTCACTACTATGTGGTTAAATATTCCAATAAAAAACA
CATCATTATTGCAGACCCAGATCCCACGGTTAAAATTCGAAAAATGACGTGGGACCAATTTTATTCTGAATGGACAGGAG
TAACTTTATTTATTGCTCCTCAACCTTCTTATAAACCAGTGAAAGAAAAATCCGAGTCTTTGTTTTCTTTTATCCCCCTC
ATCGCAAAGCAAAAGCTGCTTGTTTGTCAGATTATTATTGCTTCTCTTTTAGTCACTTTAATTAATATTATTGGCTCTTA
TTATCTTCAGAATATTATTGACGAATATGTGCCTAATGCTTTAATGAAAACTTTAGGCATTGTTTCGCTTGGATTAATGG
CAACATATTTCATCCAGCAAATTCTTAATTTTGCTCAAACTTTCTTACTTACAATACTTGGACAACGTTTAGCCATTGAT
GTTATCCTTTCCTATATCCGTCATATTTTTCAACTTCCTATGTCTTTCTTTTCTACACGAAGAACGGGAGAAATTACCAG
TCGTTTCTCTGACGCCAATTCAATTATTGATGCCCTTGCTTCTGCCATCTTATCCCTTTTCTTAGATGTCACGATTGTCA
TTCTGACAGGGCTTGTTTTAGGACTTCAAAACATGAGCTTATTCTTCCTTGTCTTGTTTTCAATTCCGCTTTATGTTCTT
ATCATTTTTATTTTTATTCCTTTATTTGAAAAACAAAATAATGAAGTCATGCAAGCAAATTCTATTTTAAATTCTTCAAT
TATTGAGGATATCAATGGAATTGAAACCATAAAATCTCTTGGGAGTGAAGAGATTCGCTATCAAAAAATAGACCGTGAAT
TTGCGGACTACATGAAAAAATCATTCACGCGTCAAAAATCCGAAGCTTTTCAAACTGCCTTGAAATCAGGATTACAACTT
GTTTTAAATGTACTTATCTTGTGGTATGGAGCCACCCTCGTGGTGAGTCAAAAAATCACCTTGGGTCAATTAATTACTTT
CAATGTCTTACTTTCATACTTTATGAATCCTCTTTCTAATATCATCAACTTACAAACTAAACTTCAATCCGCTAAAGTAG
CTAATCATCGCTTAAATGAAGTTTACTTGGTAGACAGTGAATTTGATACAAAAACAGATGAAATTATTCTTTCAAATTTT
GAGATGCAGTTGATAGGTATATCTTACCACTATGGTTTTGGTAGAGACATTCTTTCTAATATTTCACTTAATATAAAAGA
AAATGAAAAATTAACAATTGTCGGAATGAGTGGCTCAGGTAAAAGTACCCTAGTCAAATTGTTGGTTAATTTTTTCGAAC
CTACACAAGGGACTATCATTCTTGGGGGGATAGATATAAAACAAATGGATAAACATCAACTCAGAAGGATTGTCAGCTAT
CTTCCCCAACACCCCTATATCTTCACTGGAACAGTACTTGATAATTTAACCTTAGGAGTAAGTGAGGATATTTCTCAGGA
AGAAATTTTCCAAGCTGTTGAAGCTGCGGAAATTCGTTCCGATATTGAACAACTTCAATTGGGCTATCAAACGGAGCTTT
CTAGTGATGCTACAACTCTCTCTGGAGGTCAAAAACAAAGAATCGCATTGGCTCGTACCTTACTTTCTCCCGCAAAGATC
CTTATTTTTGATGAAGCAACAAGTAATCTGGACGTAATTACCGAGAAAAAAATTTTGAAAAATCTATTTAAGTTAGATAA
AACCATTATTTTTATTGCCCATCGTCTGTCTATCGCGGAAAAGAGCGACAGGATTGTTGTTATTGATCAGGGAAAAATTA
TGGAAGAAGGTAGTCATTTAGAACTGCTTTCTAAAAATGGTTTTTATGCACAACTTTATAATCAATAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (6-142)

• ABC transporter (ABC_tran) (498-648)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	60.475	100	0.606
comA	Streptococcus mitis NCTC 12261	59.637	100	0.597
comA	Streptococcus mitis SK321	59.497	100	0.596
comA/nlmT	Streptococcus mutans UA159	59.275	100	0.594
comA	Streptococcus pneumoniae D39	59.218	100	0.593
comA	Streptococcus pneumoniae R6	59.218	100	0.593
comA	Streptococcus pneumoniae Rx1	59.218	100	0.593
comA	Streptococcus pneumoniae TIGR4	58.939	100	0.59