Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   V6U70_RS07095 Genome accession   NZ_CP145868
Coordinates   1574646..1576520 (-) Length   624 a.a.
NCBI ID   WP_410532291.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS12     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1569646..1581520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U70_RS07060 (V6U70_07055) rimM 1570025..1570543 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  V6U70_RS07075 (V6U70_07070) - 1571239..1571883 (-) 645 WP_002891417.1 response regulator transcription factor -
  V6U70_RS07080 (V6U70_07075) - 1571873..1572883 (-) 1011 WP_002891418.1 sensor histidine kinase -
  V6U70_RS07085 (V6U70_07080) liaF 1572880..1573578 (-) 699 WP_073685667.1 cell wall-active antibiotics response protein LiaF -
  V6U70_RS07090 (V6U70_07085) - 1573742..1574500 (-) 759 WP_410532290.1 potassium channel family protein -
  V6U70_RS07095 (V6U70_07090) stkP/pknB 1574646..1576520 (-) 1875 WP_410532291.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  V6U70_RS07100 (V6U70_07095) - 1576520..1577257 (-) 738 WP_037604753.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  V6U70_RS07105 (V6U70_07100) rsmB 1577301..1578623 (-) 1323 WP_080610732.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  V6U70_RS07110 (V6U70_07105) fmt 1578613..1579548 (-) 936 WP_080610733.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67883.58 Da        Isoelectric Point: 6.7044

>NTDB_id=940852 V6U70_RS07095 WP_410532291.1 1574646..1576520(-) (stkP/pknB) [Streptococcus salivarius strain KSS12]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNERVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKNTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGAGFKVGEVKEV
EDDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGE
ILSQSPGKNKSFNPKGSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKNISSSSIEYHDYNTGAKLDKDKVPSSTEI
LYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=940852 V6U70_RS07095 WP_410532291.1 1574646..1576520(-) (stkP/pknB) [Streptococcus salivarius strain KSS12]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGGCGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGAGTAGCTATTAAGGTGCTACGTACCAATTACCAAACGGATCAGGTGG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTTTTGGTGATGGAGTATGTAGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTTACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACTAACTCTATGTTGGGGTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
GAAAGCAACTATCCAAAGCGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTAACAGGTCATATTCCTTACGATG
GCGATAGTGCTGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCGATTTTGGCAGAGAACCGTAACGTTCCC
CAAGCCTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTATAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TACCGAAGGTTGATCCAGTTCCATCAGCAAGTCTTGAGAAAAAAGCCGTTGCTGCTGAACCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAATACGACACCAGCTAAGAAGAAAAAGAAGAAGAACTTCTTCTCAACCTTACTCAAGGT
TTTCCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTAGTCTTTACCAATCCTGATAATGTCCAAGTACCTA
ATGTGGTCGGTCAGGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTCAAAGAAGTG
GAAGATGACTCTGTCGATACGGGTAAGGTCATCAAGACCGATCCTACAGCTGGAACCACACGAAAAGAAGGATCAAGCAT
TGATGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAGGGTAAAAACTATAAGGATGCCATTGAGG
ACTTAACTTCGAATTATGGTGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAA
ATCCTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGGTAGTAAGGCTAAGATTAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTAACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAATATCT
CAAGTAGTAGCATCGAGTACCACGACTATAATACTGGTGCCAAATTAGATAAGGATAAGGTTCCTAGCAGTACGGAGATC
CTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAGTTCAAG
TCTCCAGTCAAGCTCAAGCAGTACGACACATTCGTCATCAACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAGCTACAATAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(441-503)

PASTA domain (PASTA)

(511-580)

PASTA domain (PASTA)

(370-432)

Protein kinase domain (Pkinase)

(12-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.878

100

0.989
  pknB Streptococcus mutans UA159

67.159

86.859

0.583
  stkP Streptococcus pneumoniae TIGR4

53.345

93.429

0.498
  stkP Streptococcus pneumoniae D39

53.173

93.429

0.497
  stkP Streptococcus pneumoniae R6

53.173

93.429

0.497
  stkP Streptococcus pneumoniae Rx1

53.002

93.429

0.495