Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   V6U69_RS09340 Genome accession   NZ_CP145867
Coordinates   2016337..2017086 (-) Length   249 a.a.
NCBI ID   WP_060973231.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS10     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2011337..2022086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U69_RS09320 (V6U69_09310) - 2011659..2012891 (-) 1233 WP_037600142.1 cysteine desulfurase -
  V6U69_RS09325 (V6U69_09315) sufD 2012945..2014207 (-) 1263 WP_048790376.1 Fe-S cluster assembly protein SufD -
  V6U69_RS09330 (V6U69_09320) sufC 2014244..2015014 (-) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  V6U69_RS09335 (V6U69_09325) - 2015176..2016333 (-) 1158 WP_002889771.1 glycosyltransferase family 4 protein -
  V6U69_RS09340 (V6U69_09330) mecA 2016337..2017086 (-) 750 WP_060973231.1 adaptor protein MecA Regulator
  V6U69_RS09345 (V6U69_09335) - 2017293..2017664 (+) 372 WP_002889766.1 DUF3021 family protein -
  V6U69_RS09350 (V6U69_09340) - 2017724..2018578 (-) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  V6U69_RS09355 (V6U69_09345) - 2018784..2020331 (+) 1548 WP_022496531.1 ABC transporter substrate-binding protein/permease -
  V6U69_RS09360 (V6U69_09350) - 2020331..2021071 (+) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29026.62 Da        Isoelectric Point: 4.0182

>NTDB_id=940810 V6U69_RS09340 WP_060973231.1 2016337..2017086(-) (mecA) [Streptococcus salivarius strain KSS10]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDVYCMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=940810 V6U69_RS09340 WP_060973231.1 2016337..2017086(-) (mecA) [Streptococcus salivarius strain KSS10]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTACACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGCGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGACCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTTAACGATTTGTCAGATATGGACGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCTCT
TGAAGGTAACTTTATGGACAAGGGGGATATCGAAGCACACCATAAGCTCGAAGAACTTGAGAAGACCTTGGAAGAAGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTGGTGACCTTTACGCAAGGCTTGAAGGATGTGCCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTGTATGACAATCCTTCTTTATTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTGCAAGAGCATGCAACAATTTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

46.988

100

0.47
  mecA Streptococcus pneumoniae D39

46.988

100

0.47
  mecA Streptococcus pneumoniae R6

46.988

100

0.47
  mecA Streptococcus pneumoniae TIGR4

46.988

100

0.47