Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   V6U69_RS03000 Genome accession   NZ_CP145867
Coordinates   574603..576474 (+) Length   623 a.a.
NCBI ID   WP_410534146.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS10     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 569603..581474
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U69_RS02985 (V6U69_02985) fmt 571575..572510 (+) 936 WP_410534144.1 methionyl-tRNA formyltransferase -
  V6U69_RS02990 (V6U69_02990) rsmB 572500..573822 (+) 1323 WP_410534145.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  V6U69_RS02995 (V6U69_02995) - 573866..574603 (+) 738 WP_073687922.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  V6U69_RS03000 (V6U69_03000) stkP/pknB 574603..576474 (+) 1872 WP_410534146.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  V6U69_RS03005 (V6U69_03005) - 576620..577378 (+) 759 WP_410534147.1 potassium channel family protein -
  V6U69_RS03010 (V6U69_03010) liaF 577541..578239 (+) 699 WP_037603001.1 cell wall-active antibiotics response protein LiaF -
  V6U69_RS03015 (V6U69_03015) - 578236..579246 (+) 1011 WP_070576872.1 sensor histidine kinase -
  V6U69_RS03020 (V6U69_03020) - 579236..579880 (+) 645 WP_002884791.1 response regulator transcription factor -
  V6U69_RS03035 (V6U69_03035) rimM 580577..581095 (+) 519 WP_049545329.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67878.60 Da        Isoelectric Point: 6.5787

>NTDB_id=940779 V6U69_RS03000 WP_410534146.1 574603..576474(+) (stkP/pknB) [Streptococcus salivarius strain KSS10]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNERVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGAGFKVGEVKEVE
DDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGEI
LSQSPGKNKSFNPKDSKAKIKFRVATPKIVTMPDVTGLTVSTAVQTLNRKNISSSSIEYHDYNTGAKLDKDKVPSSTEVL
YQDPQAGTSVDGTVILYVSVATPSSNLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=940779 V6U69_RS03000 WP_410534146.1 574603..576474(+) (stkP/pknB) [Streptococcus salivarius strain KSS10]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGGCGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGAGTAGCTATTAAGGTGCTACGTACCAATTACCAAACGGATCAGGTGG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTTTTGGTGATGGAGTATGTGGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCACCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACTAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
GAAAGCAACTATCCAAAGCGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GTGACAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCTATTTTGGCAGAGAACCGTAATGTTCCC
CAAGCTTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTACAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGTGATGCCAAGGTAGTCTTTGATGATATGACGGATACTAAGACCT
TGCCGAAGGTTGATCCAGTTCCATCAGCAAGTCTTGAGAAAAAAGCCGTTGCTGCTGAACCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAACTTCTTCTCAACCTTACTCAAGGTTTT
CCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCTTATTTAGTCTTTACCAATCCTGATAATGTCCAAGTACCTAATG
TGGTCGGTCAGGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTCAAAGAAGTGGAA
GATGACTCTGTCGATACGGGTAAGGTCATCAAGACCGATCCTACAGCTGGAACCACACGAAAAGAAGGATCAAGCATTGA
TGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAGGGTAAAAACTATAAGGATGCCATTGAGGATT
TAACTTCGAATTATGGTGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAAATC
CTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCTAAGATTAAGTTCCGTGTGGCAACTCC
TAAGATAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAATATCTCAA
GTAGTAGCATCGAGTACCACGACTATAATACTGGTGCCAAATTAGATAAGGATAAGGTTCCTAGCAGTACGGAGGTCCTT
TATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACACCAAGTTCAAACCT
TCAGTCAAGCTCAAGCAGTACGACACATTCGTCATCAACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAACCT
CGACAGAGGCTACTCACACAGAACTACAATAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(369-431)

PASTA domain (PASTA)

(440-504)

Protein kinase domain (Pkinase)

(12-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.718

100

0.989
  pknB Streptococcus mutans UA159

67.159

86.998

0.584
  stkP Streptococcus pneumoniae TIGR4

58.824

79.133

0.465
  stkP Streptococcus pneumoniae D39

58.621

79.133

0.464
  stkP Streptococcus pneumoniae R6

58.621

79.133

0.464
  stkP Streptococcus pneumoniae Rx1

58.418

79.133

0.462