Detailed information NTG0940772

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: V6U69_RS02385
• Genome accession: NZ_CP145867
• Coordinates: 448771..451011 (+)
• Length: 746 a.a.
• NCBI ID: WP_410534108.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS10
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 443771..456011

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U69_RS02360 (V6U69_02360)	-	445072..445341 (-)	270	WP_008535312.1	GIY-YIG nuclease family protein	-
V6U69_RS02365 (V6U69_02365)	-	445345..446109 (-)	765	WP_410534105.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
V6U69_RS02370 (V6U69_02370)	-	446159..447094 (-)	936	WP_410534106.1	polysaccharide deacetylase family protein	-
V6U69_RS02375 (V6U69_02375)	-	447223..447978 (+)	756	WP_410534107.1	lysophospholipid acyltransferase family protein	-
V6U69_RS02380 (V6U69_02380)	comEA	448086..448781 (+)	696	WP_021143743.1	helix-hairpin-helix domain-containing protein	Machinery gene
V6U69_RS02385 (V6U69_02385)	comEC/celB	448771..451011 (+)	2241	WP_410534108.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
V6U69_RS02390 (V6U69_02390)	-	451097..452359 (+)	1263	WP_410534109.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V6U69_RS02395 (V6U69_02395)	-	452425..452970 (+)	546	WP_048673823.1	GNAT family N-acetyltransferase	-
V6U69_RS02400 (V6U69_02400)	spxR	452963..454243 (+)	1281	WP_022496137.1	CBS-HotDog domain-containing transcription factor SpxR	-
V6U69_RS02405 (V6U69_02405)	-	454283..455143 (+)	861	WP_004183173.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84356.02 Da
• Isoelectric Point: 9.6359

>NTDB_id=940772 V6U69_RS02385 WP_410534108.1 448771..451011(+) (comEC/celB) [Streptococcus salivarius strain KSS10]
MWLKKAPINLFSLSLLIAALYFTIFVTNVYAIGAFVFLMVCFLKHHWKNKAALKLVGLVGSFFLVYFLFLHHRASIQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQNYQVFYRLKSEKEQHFFKTTSQTLVLKGKITLTQATGQRNFQGFNYQSY
LASQGIYRIAQIERLDQVVPQKPLSPLAFFHQLRRRALVHIQTHFPSPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIVLLPFSLCYGLMTGWTASVLRSLVQSLLAEFGIKKLDNMGITLLLLFLL
LPHFLLTVGGVLSCSYAFLLCLFDFEDLSSLKKSIYTSLVLSIGILPFLTYYYGTFQPVSLILTAIFSIVFDSFLLPVLT
VFFALSGLVIFSQINPLFEWMESFLTWIQSWIGQPLILGKPSLFQFGLMIAVLILLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTVVDVGQGDSIFLRSMKGDTILIDVGGKVTFGTKEKWQESSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEEVAKCFKIKEICVSQGALTKPSFVKRLRTIKCPVHTLKAGDKLPMMGSNLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMASYPTLRASVLKAGHHGSKGSSSEAFLDQLHPSLALVSAGENNRYKHPNDETIERFKQRH
IKILRTDKDGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=940772 V6U69_RS02385 WP_410534108.1 448771..451011(+) (comEC/celB) [Streptococcus salivarius strain KSS10]
ATGTGGCTTAAAAAAGCGCCAATCAATCTTTTTTCCTTGTCTCTTTTAATAGCTGCCCTTTATTTTACGATTTTTGTCAC
TAATGTTTACGCTATTGGTGCTTTTGTCTTTCTTATGGTCTGTTTTTTGAAGCATCATTGGAAGAATAAGGCAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCATCATAGAGCTAGCATACAAGATAAACAA
GCCCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTATCGGTTAATGGTGAGCAATTATCCGCTATCGGTAA
GGCCAAGGGACAAAACTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTCAAGACTACTAGTCAAA
CGCTAGTATTAAAAGGGAAAATTACGTTAACCCAAGCAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGTATTTATCGAATCGCTCAGATTGAGCGCTTGGACCAAGTAGTACCTCAAAAACCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCTTTGGTTCATATCCAGACGCACTTTCCTAGTCCTATGAGACACTATATGA
CAGGCCTGCTCTTTGGGTATTTGGATAAGGAGTTTGATGAGCAGAGCCAGCTTTACACAAGTTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTACGGTCTCCTACGCTTAGGTCTTCCTAAAGA
TTATCTATTTATCGTCTTGCTGCCTTTTTCCTTATGTTATGGCCTAATGACAGGATGGACAGCTTCAGTCCTACGTTCCT
TGGTTCAAAGTTTGCTGGCTGAGTTTGGTATTAAAAAACTGGACAATATGGGAATAACCTTGCTTCTATTGTTTCTCTTG
TTACCTCATTTTCTCTTAACAGTGGGAGGTGTATTAAGTTGTTCCTATGCCTTCTTGTTGTGTTTGTTTGATTTTGAGGA
CTTGTCATCTTTAAAGAAATCAATCTATACGAGCTTGGTATTGAGTATTGGGATTTTGCCCTTTCTAACTTACTATTATG
GAACCTTTCAACCAGTTAGTTTAATTCTAACAGCGATTTTTTCCATAGTATTTGATAGCTTTCTCTTGCCTGTATTGACA
GTATTCTTTGCCCTCTCAGGACTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGTCCTTTTTGACTTG
GATACAATCCTGGATAGGTCAACCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGA
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGACTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTGTGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGTGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACGTTTGGAACTAAGGAAAAATGGCAAGAGTCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTATCTACAGGCTAGAGGAGTGTCTCAAATTGATTATCTGGTCCTGACGCATACGGACACA
GACCATATTGGTGATTTGGAAGAAGTGGCCAAGTGTTTTAAGATTAAGGAAATCTGTGTCAGTCAGGGGGCTTTGACTAA
GCCTAGCTTTGTTAAAAGACTTCGGACTATAAAATGCCCAGTTCACACTCTAAAGGCTGGCGACAAATTACCCATGATGG
GAAGCAATCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGCGGTAACAATGATTCGATAGTTCTTTACGGAAAGCTA
TTAGGAAGCAGTTTTCTGTTTACCGGTGATTTGGAAAAAGAAGGAGAGGAGGAACTAATGGCCAGTTATCCAACTTTAAG
GGCAAGCGTCCTAAAAGCTGGACACCACGGTTCAAAAGGTTCTTCGTCTGAAGCTTTTTTGGACCAGCTGCACCCCTCCC
TTGCACTTGTTTCAGCTGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACAATAGAACGTTTTAAGCAACGCCAC
ATTAAAATTTTACGAACAGATAAAGACGGGGCCATCCGTTTTAAGGGCTGGTTTAAATGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-694)

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (30-171)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48	100	0.483
comEC/celB	Streptococcus mitis NCTC 12261	47.931	100	0.481
comEC/celB	Streptococcus pneumoniae Rx1	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae D39	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae R6	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae TIGR4	46.195	100	0.464
comEC	Lactococcus lactis subsp. cremoris KW2	44.038	98.928	0.436