Detailed information NTG0940731

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: V6U68_RS07720
• Genome accession: NZ_CP145866
• Coordinates: 1689978..1692218 (-)
• Length: 746 a.a.
• NCBI ID: WP_410531574.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS9
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1684978..1697218

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U68_RS07700 (V6U68_07680)	-	1685846..1686706 (-)	861	WP_004183173.1	methionyl aminopeptidase	-
V6U68_RS07705 (V6U68_07685)	spxR	1686746..1688026 (-)	1281	WP_037598368.1	CBS-HotDog domain-containing transcription factor SpxR	-
V6U68_RS07710 (V6U68_07690)	-	1688019..1688564 (-)	546	WP_073689615.1	GNAT family N-acetyltransferase	-
V6U68_RS07715 (V6U68_07695)	-	1688630..1689892 (-)	1263	WP_073689616.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V6U68_RS07720 (V6U68_07700)	comEC/celB	1689978..1692218 (-)	2241	WP_410531574.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
V6U68_RS07725 (V6U68_07705)	comEA	1692208..1692903 (-)	696	WP_410531575.1	helix-hairpin-helix domain-containing protein	Machinery gene
V6U68_RS07730 (V6U68_07710)	-	1693012..1693767 (-)	756	WP_002948862.1	lysophospholipid acyltransferase family protein	-
V6U68_RS07735 (V6U68_07715)	-	1693897..1694832 (+)	936	WP_410531576.1	polysaccharide deacetylase family protein	-
V6U68_RS07740 (V6U68_07720)	-	1694882..1695646 (+)	765	WP_070655505.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
V6U68_RS07745 (V6U68_07725)	-	1695650..1695919 (+)	270	WP_073686127.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84486.23 Da
• Isoelectric Point: 9.6869

>NTDB_id=940731 V6U68_RS07720 WP_410531574.1 1689978..1692218(-) (comEC/celB) [Streptococcus salivarius strain KSS9]
MWLKKAPINLFSLSLLIAALYFTIFVTNVYAIGTFVFLMVCFLKHHWKNKAALKLVGLVGSFFLVYFLFLHHRASIQDKQ
APVEINQVIMVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKINLSQATAQRNFQGFNYQSY
LASQSIYRIAQINRLDHVVPQKSLSPLAFFHQLRRRALVHIQTHFPSPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIVLLPFSLCYGLMTGWTASVLRSLVQSLLAEFGIKKLDNMGITLLLLFLL
LPHFLLTVGGVLSCSYAFLLCLFDFDDLSSLKKSIYTSLVLSLGILPFLTYYYGTFQPVSLILTTIFSIVFDSFLLPVLT
VFFALSGLVIFSQINPLFEWMESFLTWIQSWIGQPLILGKPSLFQFGLMIAVLILLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTVVDVGQGDSIFLRSMKGETILIDVGGKVTFGAKEKWQESSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEEVAKCFKIKEICVSQGALTKPSFVKRLRTIKCPVHTLKAGDKLPMMGSNLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMVSYPTLRASVLKAGHHGSKGSSSEAFLDQLHPSLALVSAGENNRYKHPNDETIERFKQRH
IKILRTDKDGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=940731 V6U68_RS07720 WP_410531574.1 1689978..1692218(-) (comEC/celB) [Streptococcus salivarius strain KSS9]
ATGTGGCTTAAAAAAGCGCCAATCAATCTTTTTTCCTTGTCTCTTTTAATAGCTGCCCTTTATTTTACGATTTTTGTCAC
TAATGTTTATGCTATTGGTACTTTTGTCTTTCTTATGGTCTGTTTTTTGAAGCATCATTGGAAGAATAAGGCAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCATCATAGAGCTAGCATACAAGATAAACAA
GCTCCTGTTGAAATCAATCAGGTGATTATGGTTGCTGATACGTTATCGGTTAATGGTGAGCAATTATCAGCTATCGGTAA
GGCCAAGGGACAAACCTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CGCTAGTATTAAAAGGGAAAATAAACTTATCTCAAGCAACTGCTCAGCGTAATTTTCAAGGGTTTAATTATCAATCTTAT
CTAGCCAGTCAAAGCATTTATCGAATTGCTCAGATTAATCGCTTGGACCATGTGGTGCCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCTTTGGTTCATATCCAGACGCACTTTCCTAGTCCTATGAGACACTATATGA
CAGGCCTGCTCTTTGGGTATTTGGATAAGGAGTTCGATGAGCAGAGCCAGCTTTACACAAGTTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTACGGTCTCCTACGCTTAGGTCTTCCTAAAGA
TTATCTATTTATCGTCTTGCTGCCTTTTTCCTTATGTTATGGCTTAATGACAGGATGGACAGCTTCAGTCCTACGTTCCT
TGGTTCAAAGTTTGCTGGCTGAGTTTGGTATTAAAAAACTGGACAATATGGGAATAACCTTGCTTCTATTGTTTCTCTTG
TTACCTCATTTTCTTTTAACAGTGGGAGGTGTATTAAGTTGTTCCTATGCCTTCTTGTTGTGTTTGTTTGATTTTGATGA
CTTGTCATCTTTAAAGAAATCAATCTATACGAGCTTGGTATTGAGTCTTGGGATTTTGCCCTTTTTAACCTACTATTATG
GGACTTTTCAACCAGTTAGTTTGATTCTCACTACAATCTTTTCAATTGTATTTGATAGCTTTCTTTTGCCTGTCTTGACG
GTCTTCTTTGCCCTTTCAGGACTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGTCCTTTTTGACTTG
GATACAATCCTGGATAGGTCAACCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGA
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTGTGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
GACTATCCTAATTGATGTGGGTGGCAAGGTGACGTTTGGAGCTAAGGAAAAATGGCAAGAGTCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTATCTACAGGCTAGAGGAGTGTCTCAAATTGATTATCTAGTCCTGACGCATACGGACACA
GACCATATTGGTGATTTGGAAGAAGTGGCCAAGTGTTTTAAGATTAAGGAAATCTGTGTCAGTCAGGGGGCTTTGACTAA
GCCTAGCTTTGTTAAAAGACTTCGGACTATAAAATGCCCAGTTCACACTCTAAAGGCTGGCGACAAATTACCCATGATGG
GAAGCAATCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGCGGTAACAATGATTCGATAGTTCTTTACGGAAAGCTA
TTAGGAAGCAGTTTTCTGTTTACCGGTGATTTGGAAAAAGAAGGAGAGGAGGAACTGATGGTCAGCTATCCAACTTTAAG
GGCAAGCGTCCTCAAAGCTGGACACCACGGTTCAAAAGGTTCTTCGTCTGAAGCTTTTTTGGACCAGCTGCACCCCTCCC
TTGCACTTGTTTCAGCTGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACAATAGAACGTTTTAAGCAACGCCAC
ATTAAAATTTTACGAACAGATAAAGACGGAGCCATCCGTTTTAAGGGCTGGTTTAAATGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-694)

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (30-171)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.4	100	0.487
comEC/celB	Streptococcus mitis NCTC 12261	47.931	100	0.481
comEC/celB	Streptococcus pneumoniae Rx1	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae D39	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae R6	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae TIGR4	46.195	100	0.464
comEC	Lactococcus lactis subsp. cremoris KW2	44.054	99.196	0.437