Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   V6U68_RS02670 Genome accession   NZ_CP145866
Coordinates   530856..531599 (-) Length   247 a.a.
NCBI ID   WP_410531864.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS9     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 525856..536599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS02650 (V6U68_02645) rplJ 526949..527452 (+) 504 WP_003095623.1 50S ribosomal protein L10 -
  V6U68_RS02655 (V6U68_02650) rplL 527528..527896 (+) 369 WP_004183006.1 50S ribosomal protein L7/L12 -
  V6U68_RS02660 (V6U68_02655) - 528695..529345 (+) 651 WP_410531862.1 DUF6287 domain-containing protein -
  V6U68_RS02665 (V6U68_02660) - 529539..530846 (-) 1308 WP_410531863.1 sensor histidine kinase -
  V6U68_RS02670 (V6U68_02665) comE/blpR 530856..531599 (-) 744 WP_410531864.1 response regulator transcription factor Regulator
  V6U68_RS02675 (V6U68_02670) tnpA 532622..533094 (+) 473 Protein_479 IS200/IS605 family transposase -
  V6U68_RS02680 (V6U68_02675) - 533468..534067 (+) 600 WP_410531865.1 ATP-binding cassette domain-containing protein -
  V6U68_RS02685 (V6U68_02680) - 534064..534801 (+) 738 WP_002892541.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28667.08 Da        Isoelectric Point: 6.5033

>NTDB_id=940707 V6U68_RS02670 WP_410531864.1 530856..531599(-) (comE/blpR) [Streptococcus salivarius strain KSS9]
MLNIFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLLDAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKALDDEDFYERVHLAIEYTMNKMGATIAQDSFTFETATAQVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADNRLYRCHRSFIVNPENIVKINKEEKMVVFENNNECPISRTKYKGLLE
KVKSLKS

Nucleotide


Download         Length: 744 bp        

>NTDB_id=940707 V6U68_RS02670 WP_410531864.1 530856..531599(-) (comE/blpR) [Streptococcus salivarius strain KSS9]
TTGTTAAATATTTTTATTTTAGAAGACGAATTTTTACAACAAACACGAATAGAGACCGTTATTAAGGATGTTATTGCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTTTGGAAAACCTAGCCAGCTACTTGATGCGATTACCGAAAGAGGTTCTC
ATCAACTTTTCTTTTTAGATATTGAAATTAAAGGAGAAGAAAAAAAGGGGCTAGACATTGCGAAAGAAATCCGAAAAAAA
GATCCTAATGCAACAATTGTTTTTGTAACAACACATTCAGAATTTATGCCAGTCACTTTTAAATATAGAGTTGCTGCACT
AGATTTTATCGATAAAGCTTTGGATGATGAAGATTTTTATGAACGTGTTCATTTAGCAATTGAATATACCATGAATAAAA
TGGGTGCTACTATTGCCCAAGATTCATTTACTTTTGAAACAGCTACGGCTCAAGTTCAAGTTCCTTTTAACAATATCTTA
TTTTTTGAAACGTCTCCAACAATACATAAAGTTATTTTGCATACTAAAGAAGAACGAATGGAGTTCTACGCCAGTATTTC
AGAAGTTGAACGAGCTGACAATCGCCTATATCGATGCCATCGTTCATTTATCGTTAATCCTGAAAATATCGTTAAGATCA
ATAAAGAAGAGAAAATGGTAGTGTTTGAAAATAATAATGAATGTCCCATTTCCCGTACCAAATATAAGGGCCTCCTAGAA
AAAGTTAAATCTTTGAAAAGCTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-241)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.975

96.761

0.522
  comE/comE1 Streptococcus equinus JB1

45.679

98.381

0.449
  comE/comE2 Streptococcus equinus JB1

39.431

99.595

0.393
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.652

100

0.377
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.652

100

0.377