Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   V6U68_RS01500 Genome accession   NZ_CP145866
Coordinates   279690..280379 (+) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius strain KSS9     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 274690..285379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS01475 (V6U68_01470) - 274923..275753 (+) 831 WP_410531768.1 energy-coupling factor transporter transmembrane component T family protein -
  V6U68_RS01480 (V6U68_01475) - 275842..276513 (-) 672 WP_410531769.1 potassium channel family protein -
  V6U68_RS01485 (V6U68_01480) - 276553..277917 (-) 1365 WP_410531770.1 TrkH family potassium uptake protein -
  V6U68_RS01490 (V6U68_01485) rsmG 277986..278699 (-) 714 WP_410531771.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6U68_RS01495 (V6U68_01490) - 278998..279534 (+) 537 WP_201709529.1 DUF177 domain-containing protein -
  V6U68_RS01500 (V6U68_01495) covR 279690..280379 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6U68_RS01505 (V6U68_01500) covS 280376..281905 (+) 1530 WP_073949294.1 HAMP domain-containing histidine kinase Regulator
  V6U68_RS01510 (V6U68_01505) nrdR 282027..282506 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  V6U68_RS01515 (V6U68_01510) - 282503..283678 (+) 1176 WP_410531772.1 DnaD domain protein -
  V6U68_RS01520 (V6U68_01515) dnaI 283682..284584 (+) 903 WP_410531773.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=940696 V6U68_RS01500 WP_002883757.1 279690..280379(+) (covR) [Streptococcus salivarius strain KSS9]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=940696 V6U68_RS01500 WP_002883757.1 279690..280379(+) (covR) [Streptococcus salivarius strain KSS9]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGTGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCCCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGTGGTGCTGATGACTATATTGTAAAACCTTTTGCGATTGA
AGAACTATTGGCACGTATTCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCTAAAGCGTCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAATCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGATGCAATCGAAACAAACGTTGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGATGTTCCAGGTAAGGAAT
CATACATTCAAACAGTGCGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445