Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   V6U68_RS01505 Genome accession   NZ_CP145866
Coordinates   280376..281905 (+) Length   509 a.a.
NCBI ID   WP_073949294.1    Uniprot ID   A0A6N3AKZ1
Organism   Streptococcus salivarius strain KSS9     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 275376..286905
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS01480 (V6U68_01475) - 275842..276513 (-) 672 WP_410531769.1 potassium channel family protein -
  V6U68_RS01485 (V6U68_01480) - 276553..277917 (-) 1365 WP_410531770.1 TrkH family potassium uptake protein -
  V6U68_RS01490 (V6U68_01485) rsmG 277986..278699 (-) 714 WP_410531771.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6U68_RS01495 (V6U68_01490) - 278998..279534 (+) 537 WP_201709529.1 DUF177 domain-containing protein -
  V6U68_RS01500 (V6U68_01495) covR 279690..280379 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6U68_RS01505 (V6U68_01500) covS 280376..281905 (+) 1530 WP_073949294.1 HAMP domain-containing histidine kinase Regulator
  V6U68_RS01510 (V6U68_01505) nrdR 282027..282506 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  V6U68_RS01515 (V6U68_01510) - 282503..283678 (+) 1176 WP_410531772.1 DnaD domain protein -
  V6U68_RS01520 (V6U68_01515) dnaI 283682..284584 (+) 903 WP_410531773.1 primosomal protein DnaI -
  V6U68_RS01525 (V6U68_01520) der 284690..286000 (+) 1311 WP_410531774.1 ribosome biogenesis GTPase Der -
  V6U68_RS01530 (V6U68_01525) - 286064..286693 (+) 630 WP_110980907.1 ribonuclease P -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58080.49 Da        Isoelectric Point: 5.1853

>NTDB_id=940697 V6U68_RS01505 WP_073949294.1 280376..281905(+) (covS) [Streptococcus salivarius strain KSS9]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLFSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTIPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=940697 V6U68_RS01505 WP_073949294.1 280376..281905(+) (covS) [Streptococcus salivarius strain KSS9]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCGGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ATAACACAATTTCGAAAGTTGTTACTTATATCGAAAAGGACTGGGATTCTGATGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCTAAAAATATCTATGCATCAATCATTAATGGTGTGCTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATTTTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAAAACACAGACTCTCCTCCAGGCATGTCTGAAGTAAACAAACTGAAGTCAGTGTCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGTTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTGAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCAACTG
TGGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGCCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTACGTACGCCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAGAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAATGA
TACGTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTTGAGAGCTCAGAGCGTCCAGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAC
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATCAAGGCTCTGGAAGATGAAATGTTGGTACAAGTACA
AGATAATGGTGAAGGGATTTCTAAAGAAGATATTGAGCATATCTTTGAACGCTTCTATCGTTCAGATAAGGCACGTAATC
GTACGACAACACAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCGGATGGAGAAACGACGATACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N3AKZ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.411

100

0.994