Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   V6U68_RS00850 Genome accession   NZ_CP145866
Coordinates   154001..154750 (+) Length   249 a.a.
NCBI ID   WP_060973231.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS9     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 149001..159750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS00830 (V6U68_00830) - 150016..150756 (-) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -
  V6U68_RS00835 (V6U68_00835) - 150756..152303 (-) 1548 WP_410531730.1 ABC transporter substrate-binding protein/permease -
  V6U68_RS00840 (V6U68_00840) - 152509..153363 (+) 855 WP_037598902.1 undecaprenyl-diphosphate phosphatase -
  V6U68_RS00845 (V6U68_00845) - 153423..153794 (-) 372 WP_060973232.1 DUF3021 family protein -
  V6U68_RS00850 (V6U68_00850) mecA 154001..154750 (+) 750 WP_060973231.1 adaptor protein MecA Regulator
  V6U68_RS00855 (V6U68_00855) - 154754..155911 (+) 1158 WP_014633818.1 glycosyltransferase family 4 protein -
  V6U68_RS00860 (V6U68_00860) sufC 156074..156844 (+) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  V6U68_RS00865 (V6U68_00865) sufD 156881..158143 (+) 1263 WP_013989976.1 Fe-S cluster assembly protein SufD -
  V6U68_RS00870 (V6U68_00870) - 158197..159429 (+) 1233 WP_201041429.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29026.62 Da        Isoelectric Point: 4.0182

>NTDB_id=940689 V6U68_RS00850 WP_060973231.1 154001..154750(+) (mecA) [Streptococcus salivarius strain KSS9]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDVYCMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=940689 V6U68_RS00850 WP_060973231.1 154001..154750(+) (mecA) [Streptococcus salivarius strain KSS9]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTACACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGCGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGACCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTTAACGATTTGTCAGATATGGACGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCTCT
TGAAGGTAACTTTATGGACAAGGGGGATATCGAAGCACACCATAAGCTCGAAGAACTTGAGAAGACCTTGGAAGAAGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTGGTGACCTTTACGCAAGGCTTGAAGGATGTGCCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTGTATGACAATCCTTCTTTATTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTAGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

46.988

100

0.47
  mecA Streptococcus pneumoniae D39

46.988

100

0.47
  mecA Streptococcus pneumoniae R6

46.988

100

0.47
  mecA Streptococcus pneumoniae TIGR4

46.988

100

0.47