Detailed information NTG0940661

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: V6U67_RS07620
• Genome accession: NZ_CP145865
• Coordinates: 1681880..1684120 (-)
• Length: 746 a.a.
• NCBI ID: WP_195914563.1
• Uniprot ID: A0AB35IUU8
• Organism: Streptococcus salivarius strain KSS8
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1676880..1689120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U67_RS07600 (V6U67_07610)	-	1677744..1678604 (-)	861	WP_004183173.1	methionyl aminopeptidase	-
V6U67_RS07605 (V6U67_07615)	spxR	1678648..1679928 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
V6U67_RS07610 (V6U67_07620)	-	1679921..1680466 (-)	546	WP_049545582.1	GNAT family N-acetyltransferase	-
V6U67_RS07615 (V6U67_07625)	-	1680532..1681794 (-)	1263	WP_002884638.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V6U67_RS07620 (V6U67_07630)	comEC/celB	1681880..1684120 (-)	2241	WP_195914563.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
V6U67_RS07625 (V6U67_07635)	comEA	1684110..1684805 (-)	696	WP_272125634.1	helix-hairpin-helix domain-containing protein	Machinery gene
V6U67_RS07630 (V6U67_07640)	-	1684914..1685669 (-)	756	WP_022496132.1	lysophospholipid acyltransferase family protein	-
V6U67_RS07635 (V6U67_07645)	-	1685799..1686734 (+)	936	WP_022496131.1	polysaccharide deacetylase family protein	-
V6U67_RS07640 (V6U67_07650)	-	1686784..1687548 (+)	765	WP_022496130.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
V6U67_RS07645 (V6U67_07655)	-	1687552..1687821 (+)	270	WP_022496129.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84391.23 Da
• Isoelectric Point: 9.7747

>NTDB_id=940661 V6U67_RS07620 WP_195914563.1 1681880..1684120(-) (comEC/celB) [Streptococcus salivarius strain KSS8]
MWLKKAPINLFSLALLIAALYFTIFVTNVYAIGVLSFLLVCFLKHHWKNKAALKLVGLVGSFFLIYFLFLHHRASIQDKQ
APTAINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSQATGQRNFQGFNYQSY
LASQGIYQMAQIEHLDHVVPQKSLSPLAFFHQLRRRALVHIQTHFPTPMRHYMTGLLFGCLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLLFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFIF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTYYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFALSGLVIFSQINPLFEWMETFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMVSYPNLKASVLKAGHHGSKGSSSEAFLDQLQPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=940661 V6U67_RS07620 WP_195914563.1 1681880..1684120(-) (comEC/celB) [Streptococcus salivarius strain KSS8]
ATGTGGCTTAAAAAAGCTCCCATCAATCTTTTTTCCCTGGCTCTGTTAATAGCTGCCCTTTATTTTACGATTTTTGTCAC
TAATGTTTATGCTATTGGGGTTTTGTCTTTTCTTTTAGTATGTTTTTTGAAGCATCATTGGAAGAATAAGGCAGCCCTAA
AGTTGGTGGGGCTTGTAGGTAGTTTCTTTTTGATTTACTTTTTATTCTTGCACCACAGAGCTTCCATACAAGATAAACAA
GCTCCTACTGCAATCAATCAAGTGACTCTGGTTGCTGATACGCTGTCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACCTATCAGGTCTTTTACCGACTTAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CCTTGGTATTAAAAGGGAAAATAAAGTTATCCCAAGCAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGTATTTATCAAATGGCTCAGATTGAGCACTTGGACCATGTGGTGCCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCATTGGTTCATATCCAGACGCACTTTCCTACTCCTATGAGACACTATATGA
CAGGCCTGCTCTTTGGGTGTTTGGATAAGGAGTTTGATGAGCAAAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTTGCACTCTCAGGGATGCAAGTCGGCTTTTTTCTGGGATGGTTTCGTTATGGACTTCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATTTTGCTGCTTTTTTCCTTATGCTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCC
TGATTCAAAGTTTGTTGGCTGAGTTTGGTATTAAAAAACTGGATAATATGGGAATAACCTTGCTTCTATTGTTTATCTTT
TTACCCCATTTTCTTTTAACAGTGGGGGGTGTCTTAAGTTGTTCCTATGCCTTCTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATTTGTACGAGCTTGGTATTGAGTCTTGGGATTTTGCCTTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTATTTGATAGCTTTCTCTTGCCTGTCTTGACG
GTCTTCTTTGCCCTTTCAGGACTAGTAATCTTTTCTCAAATTAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGGTCAAAGGAAAAATGGCAAGAGGCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTACCTACAGGCTAGGGGAGTGTCTCAAATTGACCATCTGGTCCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAACGCCCAGTTCGCACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGTAGTTTTTTGTTTACGGGTGATCTAGAAAAAGAAGGAGAGGAGGAACTGATGGTCAGCTATCCTAATTTAAA
GGCTAGTGTCCTCAAAGCCGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCGTTTTTGGACCAGTTGCAGCCCTCCC
TTGCCCTTGTTTCAGCTGGAGAGAATAATCGTTATAAACATCCAAATGATGAAACTTTGGAGCGTTTCAAGGAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGTGCTATCCGTTTTAAGGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-168)

• Competence protein (Competence) (216-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.594	100	0.487
comEC/celB	Streptococcus mitis SK321	48.396	100	0.485
comEC/celB	Streptococcus pneumoniae R6	47.326	100	0.475
comEC/celB	Streptococcus pneumoniae D39	47.326	100	0.475
comEC/celB	Streptococcus pneumoniae Rx1	47.326	100	0.475
comEC/celB	Streptococcus pneumoniae TIGR4	46.988	100	0.471
comEC	Lactococcus lactis subsp. cremoris KW2	42.973	99.196	0.426