Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   V6U67_RS07010 Genome accession   NZ_CP145865
Coordinates   1555886..1557760 (-) Length   624 a.a.
NCBI ID   WP_272125658.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS8     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1550886..1562760
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS06975 (V6U67_06985) rimM 1551266..1551784 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  V6U67_RS06990 (V6U67_07000) - 1552479..1553123 (-) 645 WP_022496266.1 response regulator transcription factor -
  V6U67_RS06995 (V6U67_07005) - 1553113..1554123 (-) 1011 WP_175063016.1 sensor histidine kinase -
  V6U67_RS07000 (V6U67_07010) liaF 1554120..1554818 (-) 699 WP_022496267.1 cell wall-active antibiotics response protein LiaF -
  V6U67_RS07005 (V6U67_07015) - 1554982..1555740 (-) 759 WP_002884314.1 potassium channel family protein -
  V6U67_RS07010 (V6U67_07020) stkP/pknB 1555886..1557760 (-) 1875 WP_272125658.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  V6U67_RS07015 (V6U67_07025) - 1557760..1558497 (-) 738 WP_073687922.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  V6U67_RS07020 (V6U67_07030) rsmB 1558541..1559863 (-) 1323 WP_272125657.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  V6U67_RS07025 (V6U67_07035) fmt 1559853..1560788 (-) 936 WP_272125656.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 68027.75 Da        Isoelectric Point: 6.5790

>NTDB_id=940654 V6U67_RS07010 WP_272125658.1 1555886..1557760(-) (stkP/pknB) [Streptococcus salivarius strain KSS8]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNERVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGDGFKVGEVKEV
EDDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDNAEEGE
ILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGVKLDKDKIPSSTEV
LYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=940654 V6U67_RS07010 WP_272125658.1 1555886..1557760(-) (stkP/pknB) [Streptococcus salivarius strain KSS8]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGGCGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGAGTAGCTATTAAGGTGCTACGTACCAATTACCAAACGGATCAGGTGG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTATGTGGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCACCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACTAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
GAAAGCAACTATCCAAAGCGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GTGACAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCGATTTTGGCAGAGAACCGTAACGTTCCT
CAAGCTTTGGAAAACGTGGTAATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTATAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCAAAGGTTGATCCAGTTCCATCTGCAAGTCTTGAGAAAAAAGCCGTTGCTGCTGAGCCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAAAAACTTTTTCTCAACCTTGCTCAAGGT
TTTCCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTGGTATTTACCAATCCTGATAATGTCCAGGTGCCTA
ATGTGGTCGGTCAAGAGTTGTCCACAGCTCAGACTAAAATCGAGGGTGATGGATTTAAGGTAGGAGAAGTTAAGGAAGTG
GAAGATGACTCTGTCGATACAGGCAAGGTCATCAAGACTGATCCTACAGCTGGAACTACACGAAAAGAAGGATCAAGCAT
TGATGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAAGGTAAAAACTATAAGGATGCCATTGAGG
ACTTAACTTCGAATTATGGCGTTTCTGAGGATCAAATTGATATTCAGCATGTCGAAGACGATAATGCTGAAGAGGGAGAA
ATCCTATCTCAAAGTCCAGGAAAAAACAAGTCCTTCAACCCTAAGGATAGTAAGGCTAAGATTAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAGTATCT
CAAGTAGTAGCATCGAGTACCATGACTATAATACTGGTGTTAAGTTAGACAAGGATAAGATTCCTAGCAGTACAGAGGTC
CTTTATCAAGATCCACAAGCTGGTACAAGCGTTGATGGTACAGTGATCCTCTATGTTTCAGTTGCAACAGCAAGTTCAAG
TCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAGCTACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(511-580)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(370-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.558

100

0.986
  pknB Streptococcus mutans UA159

67.159

86.859

0.583
  stkP Streptococcus pneumoniae TIGR4

51.979

93.109

0.484
  stkP Streptococcus pneumoniae D39

51.807

93.109

0.482
  stkP Streptococcus pneumoniae R6

51.807

93.109

0.482
  stkP Streptococcus pneumoniae Rx1

51.635

93.109

0.481