Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   V6U67_RS01555 Genome accession   NZ_CP145865
Coordinates   293970..294659 (+) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius strain KSS8     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 288970..299659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS01530 (V6U67_01535) - 289202..290032 (+) 831 WP_021143559.1 energy-coupling factor transporter transmembrane component T family protein -
  V6U67_RS01535 (V6U67_01540) - 290122..290793 (-) 672 WP_022496217.1 potassium channel family protein -
  V6U67_RS01540 (V6U67_01545) - 290833..292197 (-) 1365 WP_272126742.1 TrkH family potassium uptake protein -
  V6U67_RS01545 (V6U67_01550) rsmG 292266..292979 (-) 714 WP_037610619.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6U67_RS01550 (V6U67_01555) - 293278..293814 (+) 537 WP_272126745.1 DUF177 domain-containing protein -
  V6U67_RS01555 (V6U67_01560) covR 293970..294659 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6U67_RS01560 (V6U67_01565) covS 294656..296185 (+) 1530 WP_002883784.1 HAMP domain-containing histidine kinase Regulator
  V6U67_RS01565 (V6U67_01570) nrdR 296307..296786 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  V6U67_RS01570 (V6U67_01575) - 296783..297958 (+) 1176 WP_045771723.1 DnaD domain protein -
  V6U67_RS01575 (V6U67_01580) dnaI 297962..298864 (+) 903 WP_002883792.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=940629 V6U67_RS01555 WP_002883757.1 293970..294659(+) (covR) [Streptococcus salivarius strain KSS8]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=940629 V6U67_RS01555 WP_002883757.1 293970..294659(+) (covR) [Streptococcus salivarius strain KSS8]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAACTATTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445