Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   V6U67_RS01560 Genome accession   NZ_CP145865
Coordinates   294656..296185 (+) Length   509 a.a.
NCBI ID   WP_002883784.1    Uniprot ID   A0A1V0GG48
Organism   Streptococcus salivarius strain KSS8     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 289656..301185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS01535 (V6U67_01540) - 290122..290793 (-) 672 WP_022496217.1 potassium channel family protein -
  V6U67_RS01540 (V6U67_01545) - 290833..292197 (-) 1365 WP_272126742.1 TrkH family potassium uptake protein -
  V6U67_RS01545 (V6U67_01550) rsmG 292266..292979 (-) 714 WP_037610619.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6U67_RS01550 (V6U67_01555) - 293278..293814 (+) 537 WP_272126745.1 DUF177 domain-containing protein -
  V6U67_RS01555 (V6U67_01560) covR 293970..294659 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6U67_RS01560 (V6U67_01565) covS 294656..296185 (+) 1530 WP_002883784.1 HAMP domain-containing histidine kinase Regulator
  V6U67_RS01565 (V6U67_01570) nrdR 296307..296786 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  V6U67_RS01570 (V6U67_01575) - 296783..297958 (+) 1176 WP_045771723.1 DnaD domain protein -
  V6U67_RS01575 (V6U67_01580) dnaI 297962..298864 (+) 903 WP_002883792.1 primosomal protein DnaI -
  V6U67_RS01580 (V6U67_01585) der 298969..300279 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  V6U67_RS01585 (V6U67_01590) - 300344..300973 (+) 630 WP_022495832.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58071.44 Da        Isoelectric Point: 5.1853

>NTDB_id=940630 V6U67_RS01560 WP_002883784.1 294656..296185(+) (covS) [Streptococcus salivarius strain KSS8]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=940630 V6U67_RS01560 WP_002883784.1 294656..296185(+) (covS) [Streptococcus salivarius strain KSS8]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCAGCAAATACGCTACTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCACCTAAAAATATCTATGCATCGATCATTAATGGCGTGCTTTCCGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGATTCGCCTCCAGGTATGTCCGAGGTAAACAAACTGAAGTCAGTTTCCTATAAAGGGAAGCGTGGTTTC
TTGCTACAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAAATCTTCCATGATTTGGAATTCTA
TTATGCTCTTAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCGACTG
TAGTTGTCTTGACATCTATTCTGCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTAATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGCTTCTTGAGTGACGTCAGTCATGAATTGCGTACACCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCACGAAGACTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTACAAGTACA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTATCGTTCAGATAAGGCACGTAACC
GTACGACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATTCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0GG48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

100

100

1