Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   V6U67_RS00965 Genome accession   NZ_CP145865
Coordinates   172716..173465 (+) Length   249 a.a.
NCBI ID   WP_002883698.1    Uniprot ID   A0AB33ZFG3
Organism   Streptococcus salivarius strain KSS8     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 167716..178465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS00945 (V6U67_00945) - 168729..169469 (-) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -
  V6U67_RS00950 (V6U67_00950) - 169469..171016 (-) 1548 WP_022496531.1 ABC transporter substrate-binding protein/permease -
  V6U67_RS00955 (V6U67_00955) - 171222..172076 (+) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  V6U67_RS00960 (V6U67_00960) - 172138..172509 (-) 372 WP_022496532.1 DUF3021 family protein -
  V6U67_RS00965 (V6U67_00965) mecA 172716..173465 (+) 750 WP_002883698.1 adaptor protein MecA Regulator
  V6U67_RS00970 (V6U67_00970) - 173469..174626 (+) 1158 WP_002883603.1 glycosyltransferase family 4 protein -
  V6U67_RS00975 (V6U67_00975) sufC 174788..175558 (+) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  V6U67_RS00980 (V6U67_00980) sufD 175595..176857 (+) 1263 WP_013989976.1 Fe-S cluster assembly protein SufD -
  V6U67_RS00985 (V6U67_00985) - 176911..178143 (+) 1233 WP_084915093.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29072.63 Da        Isoelectric Point: 4.0182

>NTDB_id=940622 V6U67_RS00965 WP_002883698.1 172716..173465(+) (mecA) [Streptococcus salivarius strain KSS8]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDVYYMTVLLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=940622 V6U67_RS00965 WP_002883698.1 172716..173465(+) (mecA) [Streptococcus salivarius strain KSS8]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAGGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCAGATATGGATGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCTCT
TGAGGGTAACTTTATGGACAAGGGTGACATCGAAGCACACCATAAGCTCGAAGAGCTTGAAAAGACCTTGGAAGAGGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCCTTC
TCTGACTTTGATCAAGTGGTGACTTTTACGCAAGGTTTGAAGGATGTGCCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTATATGACAGTCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

60.656

97.992

0.594
  mecA Streptococcus pneumoniae Rx1

46.988

100

0.47
  mecA Streptococcus pneumoniae D39

46.988

100

0.47
  mecA Streptococcus pneumoniae R6

46.988

100

0.47
  mecA Streptococcus pneumoniae TIGR4

46.988

100

0.47