Detailed information NTG0940600

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: V6U66_RS08980
• Genome accession: NZ_CP145864
• Coordinates: 1925243..1927399 (-)
• Length: 718 a.a.
• NCBI ID: WP_107372339.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS7
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1920243..1932399

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U66_RS08955 (V6U66_08945)	-	1920889..1921143 (-)	255	WP_021152515.1	Blp family class II bacteriocin	-
V6U66_RS08960 (V6U66_08950)	-	1921737..1922477 (+)	741	WP_164332023.1	LytR/AlgR family response regulator transcription factor	-
V6U66_RS08965 (V6U66_08955)	-	1922792..1923808 (+)	1017	WP_339313535.1	sensor histidine kinase	-
V6U66_RS08970 (V6U66_08960)	-	1923836..1923991 (-)	156	WP_021152520.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
V6U66_RS08975 (V6U66_08965)	-	1924008..1925231 (-)	1224	WP_049527520.1	HlyD family efflux transporter periplasmic adaptor subunit	-
V6U66_RS08980 (V6U66_08970)	comA/nlmT	1925243..1927399 (-)	2157	WP_107372339.1	peptide cleavage/export ABC transporter	Regulator
V6U66_RS08985 (V6U66_08975)	-	1927575..1927742 (-)	168	WP_049527517.1	hypothetical protein	-
V6U66_RS08990 (V6U66_08980)	-	1927931..1928020 (-)	90	WP_073688908.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
V6U66_RS08995 (V6U66_08985)	-	1928160..1928327 (-)	168	WP_049527516.1	hypothetical protein	-
V6U66_RS09000 (V6U66_08990)	-	1928343..1928522 (-)	180	WP_004183368.1	Blp family class II bacteriocin	-
V6U66_RS09005 (V6U66_08995)	-	1928683..1930428 (-)	1746	WP_004183369.1	ABC transporter ATP-binding protein	-
V6U66_RS09010 (V6U66_09000)	-	1930421..1932178 (-)	1758	WP_004183370.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 718 a.a.
• Molecular weight: 80566.08 Da
• Isoelectric Point: 9.4717

>NTDB_id=940600 V6U66_RS08980 WP_107372339.1 1925243..1927399(-) (comA/nlmT) [Streptococcus salivarius strain KSS7]
MFLYRRTFVPQMDIRDCGVAALASIAKYYGSDYSLAYLRELAKTTKEGTTALGIVEAAKKIGFETKAIQADMSLFNMDDV
PYPFIAHVNKEGKLQHYYVVYKNGKNKLVIGDPDPSIKVTKMSKKQFKKEWTGVALFIGPEPSYKPHKEKGIGLLAFLPL
IFKQKSLITNIVLASFLVTLVNIVGSYYLQGILDDYIPHQMRSTLGIISIGLVVSYVLQQMMTYARDYLLTILSQRFTID
VILSYVRHIFDLPMSFFATRQTGEVTSRFSDANSIIDALASTILSLFLDVSVLVVIGSILLLQNVSLFWIVLCSVPIYTI
IVLVFMKPFEKMNHKVMQSNAMVSSAIIEDINGIETIKSLTSEEIRYQKLDGEFIDYLENSFRLSKLSILQTSLKQGAQL
ILNVLILWTGAQLVMSNKISVGQLITFNTLLSYFTKPLENIINLQSKLQSAKVANARLNEVYLVESEFKETNGNIYQKQP
MNGDIIISGLSYKYGFGQDTLSDIDLTIRRGEKVSFVGVSGSGKTTLAKMIVNFYQPYKGKVSLGSQDINLIDKKSLRRK
INYLPQQSYIFSGSILENLTLGADITVTEEDILRACDIAEIRRDIEEMPMGFQTELSDGSGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLLKLTQKTIIFVAHRLSIAQRTDKIIVIEQGRLIESGSHSELMSRHGFYYRLFKK

Nucleotide

• Length: 2157 bp

>NTDB_id=940600 V6U66_RS08980 WP_107372339.1 1925243..1927399(-) (comA/nlmT) [Streptococcus salivarius strain KSS7]
ATGTTTCTTTATCGTAGGACCTTTGTTCCCCAAATGGATATTAGAGACTGTGGTGTTGCAGCTCTGGCTTCAATTGCCAA
GTATTATGGGTCGGACTATTCTTTAGCTTATCTTCGAGAATTAGCAAAGACAACCAAAGAAGGTACGACGGCTTTAGGAA
TTGTTGAAGCTGCTAAGAAAATCGGATTTGAAACAAAGGCTATTCAAGCTGACATGTCTCTATTTAACATGGATGATGTT
CCTTATCCTTTCATCGCTCATGTAAACAAAGAAGGTAAACTTCAGCATTATTATGTGGTCTATAAAAATGGAAAAAATAA
GCTAGTTATTGGTGACCCTGATCCTAGTATCAAAGTAACTAAAATGTCTAAAAAGCAATTTAAAAAGGAGTGGACGGGTG
TCGCTTTATTTATAGGACCAGAACCAAGTTACAAACCACATAAGGAAAAAGGAATCGGTCTGTTGGCTTTTCTTCCTCTC
ATTTTTAAGCAAAAATCATTAATTACTAATATTGTATTAGCTAGTTTTTTGGTTACTTTGGTAAATATTGTTGGTTCGTA
TTATCTTCAGGGGATTTTAGATGACTATATTCCTCATCAGATGAGGTCAACACTAGGAATTATTTCCATTGGCCTAGTTG
TTAGTTATGTTTTACAGCAGATGATGACATATGCTAGGGATTATCTACTGACTATCCTCAGTCAGCGTTTTACGATTGAT
GTTATTTTGTCTTACGTACGACATATTTTTGATCTTCCGATGTCTTTTTTTGCGACTAGGCAAACCGGTGAAGTTACCTC
ACGTTTTAGTGATGCCAACTCAATTATTGACGCACTAGCATCAACTATTTTGTCTCTCTTCTTAGATGTCTCTGTTCTTG
TTGTTATTGGTAGTATATTACTATTACAAAATGTTAGTTTGTTCTGGATAGTTCTTTGTTCAGTTCCTATCTATACAATA
ATAGTGCTTGTGTTCATGAAGCCCTTTGAGAAAATGAATCATAAGGTCATGCAAAGTAATGCTATGGTAAGCTCGGCTAT
TATTGAAGATATCAATGGCATTGAAACGATTAAATCTTTAACTAGTGAGGAAATTCGTTACCAAAAGCTTGATGGTGAGT
TTATAGACTATTTAGAAAATTCTTTTCGTTTGTCAAAATTATCTATTTTACAGACATCTTTAAAACAAGGAGCTCAGTTG
ATTTTAAATGTGCTCATTCTTTGGACAGGTGCTCAGTTAGTTATGTCAAATAAAATCTCAGTTGGGCAACTTATAACCTT
CAATACGTTATTGTCATATTTTACAAAGCCGTTAGAAAATATAATTAATCTTCAGAGCAAACTCCAATCTGCAAAAGTTG
CTAATGCACGTCTCAATGAGGTCTACCTTGTTGAATCGGAGTTTAAAGAAACTAATGGTAATATATATCAAAAACAGCCA
ATGAATGGAGATATTATTATTTCAGGCTTGTCCTACAAGTATGGATTTGGACAGGATACATTATCTGACATTGACTTAAC
TATTAGACGAGGTGAGAAGGTAAGTTTTGTTGGAGTCAGCGGTTCGGGAAAAACCACATTAGCGAAGATGATAGTGAATT
TTTACCAACCTTATAAAGGCAAAGTTAGCCTAGGTAGTCAAGATATCAATCTAATCGATAAAAAAAGTCTTCGTAGGAAG
ATTAACTATCTCCCTCAACAGTCCTATATTTTTAGTGGAAGTATTTTGGAAAATCTGACTTTGGGAGCCGATATAACTGT
AACAGAGGAAGATATTCTTAGAGCATGTGATATCGCTGAAATTCGGAGGGACATTGAAGAAATGCCAATGGGATTTCAAA
CGGAGCTTTCTGATGGTTCAGGGTTATCTGGAGGACAAAAGCAACGTATTGCTTTAGCGCGTGCTCTATTAACTAAAGCT
CCAGTTCTTATTTTAGATGAAGCTACAAGTGGATTAGATGTCCTAACGGAGAAGAAAGTTATAGATAATTTATTGAAATT
AACTCAAAAGACGATTATTTTTGTAGCTCATAGACTTAGTATTGCTCAAAGGACTGATAAGATAATAGTAATAGAACAGG
GGCGTTTAATAGAGAGTGGTTCACATAGTGAGTTGATGTCTAGGCATGGTTTTTACTATCGTTTATTTAAGAAATAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• ABC transporter (ABC_tran) (501-650)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	67.225	99.861	0.671
comA	Streptococcus mitis NCTC 12261	63.764	99.164	0.632
comA	Streptococcus pneumoniae Rx1	63.483	99.164	0.63
comA	Streptococcus pneumoniae D39	63.483	99.164	0.63
comA	Streptococcus pneumoniae R6	63.483	99.164	0.63
comA	Streptococcus pneumoniae TIGR4	63.343	99.164	0.628
comA	Streptococcus mitis SK321	63.343	99.164	0.628
comA	Streptococcus gordonii str. Challis substr. CH1	62.989	99.721	0.628