Detailed information NTG0940594

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: V6U66_RS08345
• Genome accession: NZ_CP145864
• Coordinates: 1799910..1802150 (-)
• Length: 746 a.a.
• NCBI ID: WP_155213929.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS7
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1794910..1807150

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U66_RS08325 (V6U66_08315)	-	1795774..1796634 (-)	861	WP_004183173.1	methionyl aminopeptidase	-
V6U66_RS08330 (V6U66_08320)	spxR	1796678..1797958 (-)	1281	WP_410534456.1	CBS-HotDog domain-containing transcription factor SpxR	-
V6U66_RS08335 (V6U66_08325)	-	1797951..1798496 (-)	546	WP_013991031.1	GNAT family N-acetyltransferase	-
V6U66_RS08340 (V6U66_08330)	-	1798562..1799824 (-)	1263	WP_013991032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V6U66_RS08345 (V6U66_08335)	comEC/celB	1799910..1802150 (-)	2241	WP_155213929.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
V6U66_RS08350 (V6U66_08340)	comEA	1802140..1802838 (-)	699	WP_084870986.1	helix-hairpin-helix domain-containing protein	Machinery gene
V6U66_RS08355 (V6U66_08345)	-	1802947..1803702 (-)	756	WP_084870987.1	lysophospholipid acyltransferase family protein	-
V6U66_RS08360 (V6U66_08350)	-	1803832..1804767 (+)	936	WP_118172091.1	polysaccharide deacetylase family protein	-
V6U66_RS08365 (V6U66_08355)	-	1804817..1805581 (+)	765	WP_118172087.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
V6U66_RS08370 (V6U66_08360)	-	1805585..1805854 (+)	270	WP_118172086.1	GIY-YIG nuclease family protein	-
V6U66_RS08375 (V6U66_08365)	-	1805946..1806332 (-)	387	WP_002886743.1	IS110 family transposase	-
V6U66_RS08380 (V6U66_08370)	-	1806352..1807113 (-)	762	WP_002886742.1	IS110 family transposase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84524.52 Da
• Isoelectric Point: 9.9425

>NTDB_id=940594 V6U66_RS08345 WP_155213929.1 1799910..1802150(-) (comEC/celB) [Streptococcus salivarius strain KSS7]
MWLKKAPINLFSLALLIAALYFTIFVTNVYAMGAFAFLLVCFLKHHWKNKAALKLVGLVGGFFLIYFLFLHHRASIQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKYEKEQHFFKTTSQTLVLKGKIKLSPATGQRNFQGFNYQSY
LASQGIYRMAQIEHLDHVVPQKSLSPLAFLHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLLIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTYYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFVLSGLVIFSQINPLFEWMETFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRVCLLMIFSLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKALIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVTKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKIGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMVSYPNLKASVLKAGHHGSKGSSSEAFLDQLHPSLALVSAGENNRYKHPNDETLKRFKKRH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=940594 V6U66_RS08345 WP_155213929.1 1799910..1802150(-) (comEC/celB) [Streptococcus salivarius strain KSS7]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCTCTTTATTTTACGATTTTTGTCAC
TAATGTTTATGCTATGGGGGCTTTTGCTTTTCTTTTAGTATGTTTTTTGAAGCATCATTGGAAGAATAAGGCAGCCCTAA
AGTTGGTGGGGCTTGTAGGTGGGTTCTTTTTGATTTATTTTTTATTCTTGCATCACAGAGCTAGCATACAAGATAAACAA
GCTCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTATCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACTTATCAGGTCTTTTACCGACTCAAATATGAGAAGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CGCTAGTACTAAAAGGAAAAATAAAGTTATCCCCAGCAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGCATTTATCGAATGGCTCAGATTGAGCACTTGGACCATGTGGTGCCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTACATCAACTGAGGAGGAGGGCATTGGTTCATATCCAGACGCACTTTCCTAATCCTATGAGACACTATATGA
CAGGCCTGCTCTTTGGGTATTTGGATAAGGAGTTTGATGAGCAGAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTCGCACTTTCAGGGATGCAAGTCGGCTTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTAATTATCTTGCTACCTTTTTCCTTATGCTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCT
TGATTCAAAGTTTGTTGGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGTATAACCTTGCTTTTATTGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTCTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGCTTGGTATTGAGTCTTGGGATTTTGCCCTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTCTTTGATAGCTTTCTCTTACCTGTCTTGACG
GTCTTCTTTGTCCTTTCAGGACTAGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCCCAGTTTAGGGTTTGTCTTTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGCTCAAAGGAAAAATGGCAAGAGGCTAGTCAGACGAGCAATG
CGGAGAAAGCCTTGATTCCCTATCTACAGGCTAGGGGAGTGTCTCAAATTGACCATCTGGTCCTGACTCATACGGACACA
GACCATATTGGTGATTTGGAAGAAGTGACCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAACGCCCAGTTCGCACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAATTGGTGATGGTGGTAACAATGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGCAGTTTTCTGTTTACTGGTGATTTGGAAAAAGAAGGAGAGGAGGAACTGATGGTCAGCTATCCTAATTTAAA
GGCCAGTGTCCTCAAAGCCGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCTTTTTTGGACCAGCTGCATCCCTCCC
TTGCACTTGTTTCAGCCGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACTTTGAAGCGTTTTAAGAAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGCGCTATCCGTTTTAAGGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-169)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-696)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.525	100	0.485
comEC/celB	Streptococcus mitis SK321	48.327	100	0.484
comEC/celB	Streptococcus pneumoniae R6	47.523	100	0.476
comEC/celB	Streptococcus pneumoniae D39	47.523	100	0.476
comEC/celB	Streptococcus pneumoniae Rx1	47.523	100	0.476
comEC/celB	Streptococcus pneumoniae TIGR4	47.256	100	0.473
comEC	Lactococcus lactis subsp. cremoris KW2	43.243	99.196	0.429