Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   V6U66_RS03310 Genome accession   NZ_CP145864
Coordinates   636708..638588 (+) Length   626 a.a.
NCBI ID   WP_049527645.1    Uniprot ID   A0AAW7PHX3
Organism   Streptococcus salivarius strain KSS7     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 631708..643588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS03295 (V6U66_03295) fmt 633680..634615 (+) 936 WP_049527649.1 methionyl-tRNA formyltransferase -
  V6U66_RS03300 (V6U66_03300) rsmB 634605..635927 (+) 1323 WP_049527646.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  V6U66_RS03305 (V6U66_03305) - 635971..636708 (+) 738 WP_002886859.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  V6U66_RS03310 (V6U66_03310) stkP/pknB 636708..638588 (+) 1881 WP_049527645.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  V6U66_RS03315 (V6U66_03315) - 638734..639492 (+) 759 WP_049527642.1 potassium channel family protein -
  V6U66_RS03320 (V6U66_03320) liaF 639656..640354 (+) 699 WP_002886862.1 cell wall-active antibiotics response protein LiaF -
  V6U66_RS03325 (V6U66_03325) - 640351..641361 (+) 1011 WP_013990239.1 sensor histidine kinase -
  V6U66_RS03330 (V6U66_03330) - 641351..641995 (+) 645 WP_002884791.1 response regulator transcription factor -
  V6U66_RS03345 (V6U66_03345) rimM 642690..643208 (+) 519 WP_002884411.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 68129.84 Da        Isoelectric Point: 7.6981

>NTDB_id=940576 V6U66_RS03310 WP_049527645.1 636708..638588(+) (stkP/pknB) [Streptococcus salivarius strain KSS7]
MIQVGKLFAGRYRILKAIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEILSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGRIPYDGDSAVTIALQHFQKPLPSILAENHNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLYPSHSRDAKVVFDDMTDTKTLPKVTPVPSVSSEKKATAKSSESKQAV
SKQPRKNSTLAKNKKKKKKKSFFSTSLKVFLGLVFIGIIIFAYLVFTNPDSTQVPNVVGQELSTAQTKIEGAGFKVGEVK
EVEDDSVDTGKVIKTDPTAGTTRKEGSSIDIYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEE
GEILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSST
EVLYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTESTSSSTETPTEATHADQQ

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=940576 V6U66_RS03310 WP_049527645.1 636708..638588(+) (stkP/pknB) [Streptococcus salivarius strain KSS7]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAAGCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATCTTGGATAATGAGAAAGTGGCCATTAAGGTGCTTCGTACTAATTATCAAACCGATCAGGTAG
CTGTGGCACGTTTCCAGCGTGAAGCACGTGCCATGGCAGAACTCAGTCATCCCAATATCGTTGCAATCCGAGACATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTACGTGGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATTATGGGAGAGATTCTTTCTGCCATGACTCTTGCCCATCAAAAGGGTATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTAGGGCCAAAGTTACAGACTTCGGGATTGCGGTTGCC
TTTGCAGAGACTAGTCTGACTCAAACCAATTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCGCGTGGATC
TAAAGCAACTATCCAAAGTGATATCTATGCTATGGGTATCATGCTCTTTGAAATGTTGACAGGGCGTATTCCATATGATG
GTGATAGTGCAGTTACCATCGCTCTTCAGCATTTCCAAAAACCATTACCATCAATCTTGGCTGAGAATCATAATGTTCCT
CAGGCATTGGAAAATGTGGTTATTCGAGCGACAGCTAAAAAGCTTGAAAATCGTTATAACAGTACTTTGGAAATGAGCCG
AGATTTAGTAACTAGCTTATATCCTAGCCATAGCCGTGATGCGAAGGTAGTCTTTGATGACATGACGGATACTAAGACTT
TGCCTAAGGTTACTCCAGTTCCGTCAGTAAGCTCTGAGAAAAAGGCAACTGCCAAGTCATCAGAGTCAAAACAAGCTGTA
AGTAAGCAACCAAGGAAAAATTCAACACTAGCTAAGAATAAAAAGAAGAAAAAAAAGAAAAGCTTTTTCTCGACATCACT
CAAGGTATTCCTGGGGTTGGTCTTTATCGGGATTATCATTTTTGCCTATTTGGTATTTACCAACCCTGATAGTACTCAGG
TGCCTAACGTGGTCGGTCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGTGAAGTTAAG
GAAGTGGAAGATGACTCTGTCGATACAGGCAAGGTCATCAAGACTGATCCTACAGCTGGAACCACACGAAAAGAAGGATC
AAGCATTGATATCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAAGGTAAAAATTATAAGGATGCCA
TTGAGGATTTAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAG
GGAGAAATCCTATCTCAAAGTCCAGGTAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCCAAGATTAAGTTCCGTGT
GGCAACTCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGA
GTATCTCAAGTAGTAGCATCGAGTATCATGACTATAATACTGGTGCTAAGTTAGACAAGGATAAGGTTCCTAGCAGTACA
GAGGTCCTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAG
TTCAAGCCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGAAAGCACAAGCTCTAGTA
CTGAAACACCGACAGAGGCTACTCACGCAGACCAACAATAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(443-507)

PASTA domain (PASTA)

(513-582)

PASTA domain (PASTA)

(373-434)

Protein kinase domain (Pkinase)

(12-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

93.142

100

0.933
  pknB Streptococcus mutans UA159

65.809

86.901

0.572
  stkP Streptococcus pneumoniae TIGR4

51.458

93.131

0.479
  stkP Streptococcus pneumoniae D39

51.286

93.131

0.478
  stkP Streptococcus pneumoniae R6

51.286

93.131

0.478
  stkP Streptococcus pneumoniae Rx1

51.115

93.131

0.476