Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   V6U66_RS00905 Genome accession   NZ_CP145864
Coordinates   158802..159551 (+) Length   249 a.a.
NCBI ID   WP_014633817.1    Uniprot ID   A0AB35IU89
Organism   Streptococcus salivarius strain KSS7     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 153802..164551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS00885 (V6U66_00885) - 154815..155555 (-) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -
  V6U66_RS00890 (V6U66_00890) - 155555..157102 (-) 1548 WP_195436013.1 ABC transporter substrate-binding protein/permease -
  V6U66_RS00895 (V6U66_00895) - 157308..158162 (+) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  V6U66_RS00900 (V6U66_00900) - 158224..158595 (-) 372 WP_041826644.1 DUF3021 family protein -
  V6U66_RS00905 (V6U66_00905) mecA 158802..159551 (+) 750 WP_014633817.1 adaptor protein MecA Regulator
  V6U66_RS00910 (V6U66_00910) - 159555..160712 (+) 1158 WP_014633818.1 glycosyltransferase family 4 protein -
  V6U66_RS00915 (V6U66_00915) sufC 160875..161645 (+) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  V6U66_RS00920 (V6U66_00920) sufD 161682..162944 (+) 1263 WP_013989976.1 Fe-S cluster assembly protein SufD -
  V6U66_RS00925 (V6U66_00925) - 162998..164230 (+) 1233 WP_410534511.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29100.68 Da        Isoelectric Point: 4.0182

>NTDB_id=940550 V6U66_RS00905 WP_014633817.1 158802..159551(+) (mecA) [Streptococcus salivarius strain KSS7]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDIPVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=940550 V6U66_RS00905 WP_014633817.1 158802..159551(+) (mecA) [Streptococcus salivarius strain KSS7]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAGGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGAATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCAGATATGGATGACTATTCAGGGCTTTCTCCAGAAGAGTTTCTAAAGGCCCT
TGAGGGTAACTTTATGGACAAGGGTGACATCGAAGCACACCATAAGCTCGAAGAGCTTGAAAAGACCTTGGAAGAGGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCCTTC
TCTGACTTTGATCAAGTGGTGACTTTTACGCAAGGTTTGAAGGATATACCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTACATGACGATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTAGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474