Detailed information NTG0940524

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: V6U65_RS07685
• Genome accession: NZ_CP145863
• Coordinates: 1693239..1695479 (-)
• Length: 746 a.a.
• NCBI ID: WP_410532321.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS6
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1688239..1700479

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U65_RS07665 (V6U65_07660)	-	1689107..1689967 (-)	861	WP_247915323.1	methionyl aminopeptidase	-
V6U65_RS07670 (V6U65_07665)	spxR	1690007..1691287 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
V6U65_RS07675 (V6U65_07670)	-	1691280..1691825 (-)	546	WP_410532319.1	GNAT family N-acetyltransferase	-
V6U65_RS07680 (V6U65_07675)	-	1691891..1693153 (-)	1263	WP_410532320.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V6U65_RS07685 (V6U65_07680)	comEC/celB	1693239..1695479 (-)	2241	WP_410532321.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
V6U65_RS07690 (V6U65_07685)	comEA	1695469..1696164 (-)	696	WP_410532322.1	helix-hairpin-helix domain-containing protein	Machinery gene
V6U65_RS07695 (V6U65_07690)	-	1696273..1697028 (-)	756	WP_037599200.1	lysophospholipid acyltransferase family protein	-
V6U65_RS07700 (V6U65_07695)	-	1697159..1698094 (+)	936	WP_175061944.1	polysaccharide deacetylase family protein	-
V6U65_RS07705 (V6U65_07700)	-	1698144..1698908 (+)	765	WP_175061945.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
V6U65_RS07710 (V6U65_07705)	-	1698912..1699181 (+)	270	WP_410532323.1	GIY-YIG nuclease family protein	-
V6U65_RS07715 (V6U65_07710)	-	1699248..1699718 (-)	471	WP_410532324.1	hypothetical protein	-
V6U65_RS07720 (V6U65_07715)	-	1699721..1700233 (-)	513	WP_410532325.1	hypothetical protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84492.38 Da
• Isoelectric Point: 9.8887

>NTDB_id=940524 V6U65_RS07685 WP_410532321.1 1693239..1695479(-) (comEC/celB) [Streptococcus salivarius strain KSS6]
MWLKKAPISLFSLSLLIAALYFTIFITNVYAIGTFVFLMVCFLKHHWKNKTALKLVGLVGSFFLVYFLFLHHRASIQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSPATGQRNFQGFNYQSY
LASQGIYRIAQIERLDQVVPQKSLSPLAFFHQLRRRALVHIQTNFPSPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIVLLPFSLCYGLMTGWTVSVLRSLVQSLLAEFGIKKLDNMGITLLLLFLL
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTYYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFALSGLLVFSQINPLFEWMEAFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKTLIPYLQARGVSQIDHMVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKIGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMASYPTLRASVLKAGHHGSKGSSSEVFLDQLHPSLALVSAGENNRYKHPNDETLERFKQRH
IKVLRTDKDGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=940524 V6U65_RS07685 WP_410532321.1 1693239..1695479(-) (comEC/celB) [Streptococcus salivarius strain KSS6]
ATGTGGCTTAAAAAAGCGCCAATCAGTCTTTTTTCCTTGTCTCTTTTAATAGCTGCCCTTTATTTTACGATTTTTATCAC
TAATGTTTATGCTATTGGGACTTTTGTCTTTCTGATGGTCTGTTTTTTGAAGCATCATTGGAAGAATAAGACAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCATCATAGAGCTAGCATACAAGATAAACAA
GCCCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTATCGGTTAATGGTGAGCAATTATCCGCTATCGGTAA
GGCAAAGGGACAAACCTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CCTTGGTATTAAAAGGAAAAATAAAGTTATCCCCAGCAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAATCTTAT
CTAGCCAGTCAAGGTATTTATCGAATCGCTCAGATTGAGCGCTTGGACCAAGTAGTACCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCTTTGGTTCATATCCAGACGAACTTTCCCAGTCCTATGAGACACTATATGA
CAGGCCTGCTCTTTGGGTATTTGGATAAGGAGTTCGATGAGCAGAGCCAGCTTTACACAAGTTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTACGGTCTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATCGTCTTGCTGCCTTTTTCCTTATGTTATGGCCTAATGACAGGATGGACAGTTTCAGTCCTACGTTCCT
TGGTTCAAAGTTTGCTGGCTGAGTTTGGTATTAAAAAACTGGACAATATGGGAATAACCTTGCTTCTATTGTTTCTCTTG
TTACCTCATTTTCTCTTAACAGTGGGAGGTGTATTAAGTTGTTCCTATGCCTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCACTTAAAAAGTCAATCTGTACAAGCTTAGTGTTGAGTCTTGGGATTTTGCCTTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTATTTGATAGTTTTCTCTTACCTGTCTTGACG
GTATTCTTTGCCCTTTCTGGACTGCTAGTCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGGCCTTTTTGACTTG
GATACAATCCTGGATAGGTCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAATTTGGCTTGATGATAGCTGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGTTCAAAGGAAAAATGGCAAGAGGCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTATCTACAGGCTAGGGGAGTGTCTCAAATTGACCATATGGTCCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGTGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAACGCCCAGTTCGTACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGCAAGCTACAGGTTCTTTATCCAAATAAAATTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGCAGTTTTTTGTTTACTGGTGATTTGGAAAAAGAAGGAGAGGAGGAGCTGATGGCCAGCTATCCAACTTTAAG
GGCAAGCGTCCTCAAAGCTGGACACCACGGTTCAAAAGGCTCATCGTCTGAAGTTTTTTTGGATCAGTTGCACCCCTCCC
TTGCACTTGTTTCAGCTGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACATTAGAACGTTTTAAGCAACGTCAC
ATTAAGGTTTTACGAACAGATAAAGACGGAGCCATACGTTTTAAGGGTTGGTTTAAATGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-689)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.594	100	0.487
comEC/celB	Streptococcus mitis SK321	48.262	100	0.484
comEC/celB	Streptococcus pneumoniae Rx1	46.925	100	0.471
comEC/celB	Streptococcus pneumoniae D39	46.925	100	0.471
comEC/celB	Streptococcus pneumoniae R6	46.925	100	0.471
comEC/celB	Streptococcus pneumoniae TIGR4	46.586	100	0.466
comEC	Lactococcus lactis subsp. cremoris KW2	43.378	99.196	0.43