Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   V6U65_RS05685 Genome accession   NZ_CP145863
Coordinates   1175628..1177043 (-) Length   471 a.a.
NCBI ID   WP_410532152.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS6     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1170628..1182043
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U65_RS05655 (V6U65_05650) - 1171266..1171664 (-) 399 WP_037600754.1 cytidine deaminase -
  V6U65_RS05660 (V6U65_05655) deoC 1171651..1172313 (-) 663 WP_073688944.1 deoxyribose-phosphate aldolase -
  V6U65_RS05665 (V6U65_05660) - 1172347..1173624 (-) 1278 WP_410532149.1 pyrimidine-nucleoside phosphorylase -
  V6U65_RS05670 (V6U65_05665) - 1173621..1174211 (-) 591 WP_410532150.1 class I SAM-dependent methyltransferase -
  V6U65_RS05675 (V6U65_05670) coaA 1174324..1175244 (+) 921 WP_013990467.1 type I pantothenate kinase -
  V6U65_RS05680 (V6U65_05675) rpsT 1175314..1175550 (+) 237 WP_004182129.1 30S ribosomal protein S20 -
  V6U65_RS05685 (V6U65_05680) ciaH 1175628..1177043 (-) 1416 WP_410532152.1 sensor histidine kinase Regulator
  V6U65_RS05690 (V6U65_05685) ciaR 1177033..1177707 (-) 675 WP_002891134.1 response regulator transcription factor Regulator
  V6U65_RS05695 (V6U65_05690) - 1177906..1179576 (-) 1671 WP_004182072.1 formate--tetrahydrofolate ligase -
  V6U65_RS05700 (V6U65_05695) - 1179771..1180454 (+) 684 WP_002891136.1 phosphopantothenate--cysteine ligase -
  V6U65_RS05705 (V6U65_05700) coaC 1180447..1180992 (+) 546 WP_021144029.1 phosphopantothenoylcysteine decarboxylase -
  V6U65_RS05710 (V6U65_05705) - 1181021..1181593 (+) 573 WP_021144028.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53490.26 Da        Isoelectric Point: 8.7661

>NTDB_id=940513 V6U65_RS05685 WP_410532152.1 1175628..1177043(-) (ciaH) [Streptococcus salivarius strain KSS6]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTGQNQVSRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=940513 V6U65_RS05685 WP_410532152.1 1175628..1177043(-) (ciaH) [Streptococcus salivarius strain KSS6]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAGACCAATTCTTATTTAGAAATGGAAATGCTCAAACGGGAACTTTTTCTGACTTCTGAG
GTGGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCGACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAAAATTGAAGATGCCCCTCACGATTTATCAGTTGCCGCAAATACCAGTGTCT
TGGTACTTGATAAGAATGGAAAAGTCCTTAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGATAAAAAT
AATATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAGAAAGT
AGATAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTTAAGCTAATTGTCATCATGATGAGTTTCTTCTGGCTTTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAGAATGCTAGCCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGTACTATTTTAGATAATTCAGAGAATATTGCATCAA
GTCTTGATGAAGTTCGTAATATGCGTCTGTTGACTACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGGTCAAAACCAAGTTAGTCGTCCAATCCAAACTGATAAAACGCTATTGAAACAGTTAATGACCATTTTATTTG
ATAATGCTATTAAATATACGGAAGATGACGGACATGTTACCTTTACTGTCCGCACTAACGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCTCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATTACCGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.739

97.665

0.554
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495