Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   V6U65_RS01375 Genome accession   NZ_CP145863
Coordinates   255040..257136 (+) Length   698 a.a.
NCBI ID   WP_410532572.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS6     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 250040..262136
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U65_RS01350 (V6U65_01350) trkA 250140..251489 (-) 1350 WP_048790668.1 Trk system potassium transporter TrkA -
  V6U65_RS01355 (V6U65_01355) - 251767..252276 (+) 510 WP_048790669.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  V6U65_RS01360 (V6U65_01360) - 252587..253144 (+) 558 WP_037598980.1 ECF transporter S component -
  V6U65_RS01365 (V6U65_01365) - 253147..253797 (+) 651 WP_410532570.1 phosphatase PAP2 family protein -
  V6U65_RS01370 (V6U65_01370) comR 253975..254874 (+) 900 WP_048790671.1 helix-turn-helix transcriptional regulator Regulator
  V6U65_RS01375 (V6U65_01375) comA 255040..257136 (+) 2097 WP_410532572.1 peptide cleavage/export ABC transporter Regulator
  V6U65_RS01380 (V6U65_01380) - 257247..257579 (+) 333 WP_060972183.1 DUF805 domain-containing protein -
  V6U65_RS01385 (V6U65_01385) - 257630..259024 (-) 1395 WP_410532574.1 DUF4153 domain-containing protein -
  V6U65_RS01390 (V6U65_01390) - 259428..259943 (+) 516 WP_048790674.1 AmiS/UreI family transporter -
  V6U65_RS01395 (V6U65_01395) - 259968..260270 (+) 303 WP_002886558.1 urease subunit gamma -
  V6U65_RS01400 (V6U65_01400) - 260282..260593 (+) 312 WP_002886559.1 urease subunit beta -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78555.59 Da        Isoelectric Point: 9.2664

>NTDB_id=940492 V6U65_RS01375 WP_410532572.1 255040..257136(+) (comA) [Streptococcus salivarius strain KSS6]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQENLSY
PFIVHVVKEGGLQHYYTVFGQIKGQLVIGDPDPSKKVIKMPLEEFSKEWTGVALFFVPGEAYTKYKEDVSGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQAIIDRLIPQGAYNLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLFLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALIVQNQSLFLMTLTVVPLYVLII
VAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYREIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAF
KGVSHRFSYQQETLSKIDLTIYKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVILDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSPNFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=940492 V6U65_RS01375 WP_410532572.1 255040..257136(+) (comA) [Streptococcus salivarius strain KSS6]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGAGAGTTGGCTCAGACTTCTCGTGAAGGTACTTCTGCGCTTGGTTTGGTGG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAACCTATCTTAT
CCTTTTATTGTACATGTGGTTAAAGAAGGTGGGCTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGCAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAATTTTCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAGCCTATACTAAATACAAAGAAGATGTATCTGGACTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTGCTGAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAAGCTATTATCGACCGCTTGATTCCTCAGGGGGCCTATAATCTTCTGACCATGATTTCGCTAGGCTTATGTATCTCTT
ATCTTGCTCAACAAGTTTTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGTAATTACCTGTCCATTGCTGTCATT
CTTCCTTATATCAAGCATGTCCTTTTCTTGCCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACGTCACGTTT
TGGAGATGCTAACACTATTATTGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTGTACAAAATCAGTCACTTTTTTTGATGACTCTCACGGTAGTTCCTCTTTATGTTTTAATCATT
GTGGCATTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTTAATACCGCTGTTATTGA
TGATTTGCGAGGTATTGAAACTTTAAAATCCTTGAGGGTTGAGGAAAGACGCTATCGGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGGTTAAAGACAGGGGTTCAGTTAGTTTCT
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTCATGGAAGGGCAACTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGTTGAATTATTTTACAACTCCTTTAATTAATATCATCAATCTCCAATCTAAAATTCAGCAAGCCAAAGTCGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGACAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCTTTTAAACAACTTGCTTTT
AAAGGAGTCAGTCACCGTTTTAGTTATCAGCAAGAGACTCTTAGTAAGATTGATTTAACGATTTATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGAAAAACGACCTTAGCTAAAATGTTGTCAGGTTATTATACGAAATCTAGTGGTC
ATGTAATCCTAGATAAAGATGCTATTAGCCATGCGGAGTTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACGGGAACCATTTTAGAAAATCTGCTATTAGGATTTGAAGGAGAAGTTGACGAGAAAAAACTTCTTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGCTTTCAGACCCAAGTATCTGAAGATGGAGGTCTGTCTG
GCGGTCAAAAACAAAGATTAGCTATAGCAAGGGCTCTATTGTCCAAACAACCAATCTTGATTTTTGATGAAGCTACAAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAACCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTACGTCAACATGTCAGTCGTGTAGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(494-640)

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter transmembrane region (ABC_membrane)

(167-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.546

98.997

0.53
  comA Streptococcus gordonii str. Challis substr. CH1

53.017

99.713

0.529
  comA Streptococcus pneumoniae Rx1

53.111

98.997

0.526
  comA Streptococcus pneumoniae D39

53.111

98.997

0.526
  comA Streptococcus pneumoniae R6

53.111

98.997

0.526
  comA Streptococcus mitis NCTC 12261

53.111

98.997

0.526
  comA Streptococcus pneumoniae TIGR4

52.967

98.997

0.524
  comA/nlmT Streptococcus mutans UA159

50.58

98.854

0.5