Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   V6U65_RS00920 Genome accession   NZ_CP145863
Coordinates   163719..164468 (+) Length   249 a.a.
NCBI ID   WP_270537392.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS6     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 158719..169468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U65_RS00900 (V6U65_00900) - 159733..160473 (-) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  V6U65_RS00905 (V6U65_00905) - 160473..162020 (-) 1548 WP_096832763.1 ABC transporter substrate-binding protein/permease -
  V6U65_RS00910 (V6U65_00910) - 162226..163080 (+) 855 WP_410532522.1 undecaprenyl-diphosphate phosphatase -
  V6U65_RS00915 (V6U65_00915) - 163141..163512 (-) 372 WP_195914728.1 DUF3021 family protein -
  V6U65_RS00920 (V6U65_00920) mecA 163719..164468 (+) 750 WP_270537392.1 adaptor protein MecA Regulator
  V6U65_RS00925 (V6U65_00925) - 164472..165629 (+) 1158 WP_410532524.1 glycosyltransferase family 4 protein -
  V6U65_RS00930 (V6U65_00930) sufC 165792..166562 (+) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  V6U65_RS00935 (V6U65_00935) sufD 166599..167861 (+) 1263 WP_410532526.1 Fe-S cluster assembly protein SufD -
  V6U65_RS00940 (V6U65_00940) - 167915..169147 (+) 1233 WP_410532528.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29114.71 Da        Isoelectric Point: 4.0182

>NTDB_id=940486 V6U65_RS00920 WP_270537392.1 163719..164468(+) (mecA) [Streptococcus salivarius strain KSS6]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVVEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=940486 V6U65_RS00920 WP_270537392.1 163719..164468(+) (mecA) [Streptococcus salivarius strain KSS6]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAGGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTAACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCAGATATGGATGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCCCT
TGAGGGTAACTTTATGGACAAGGGTGACATCGAAGCACACCATAAGCTGGAAGAGCTTGAAAAGACCTTGGAAGAGGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGTTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCCTTC
TCTGATTTTGATCAAGTGGTGACCTTTACACAAGGTTTGAAGGATGTACCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTACATGACGATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474