Detailed information NTG0940457

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: V6U64_RS07515
• Genome accession: NZ_CP145862
• Coordinates: 1643072..1643815 (+)
• Length: 247 a.a.
• NCBI ID: WP_101799772.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS4
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1638072..1648815

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U64_RS07485 (V6U64_07485)	-	1638367..1638693 (-)	327	WP_410537225.1	LysR substrate-binding domain-containing protein	-
V6U64_RS07490 (V6U64_07490)	-	1638682..1638855 (-)	174	Protein_1462	LysR family transcriptional regulator	-
V6U64_RS07495 (V6U64_07495)	-	1638865..1640418 (-)	1554	WP_037605638.1	BCCT family transporter	-
V6U64_RS07500 (V6U64_07500)	-	1640646..1641227 (-)	582	WP_195968915.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	-
V6U64_RS07505 (V6U64_07505)	-	1641285..1641494 (-)	210	Protein_1465	CHAP domain-containing protein	-
V6U64_RS07510 (V6U64_07510)	-	1641868..1642125 (-)	258	Protein_1466	type II toxin-antitoxin system Phd/YefM family antitoxin	-
V6U64_RS07515 (V6U64_07515)	comE/blpR	1643072..1643815 (+)	744	WP_101799772.1	response regulator transcription factor	Regulator
V6U64_RS07520 (V6U64_07520)	-	1643825..1645132 (+)	1308	WP_410536420.1	sensor histidine kinase	-
V6U64_RS07525 (V6U64_07525)	-	1645372..1645938 (-)	567	WP_410536422.1	transcriptional regulator	-
V6U64_RS07530 (V6U64_07530)	rplL	1646724..1647092 (-)	369	WP_004183006.1	50S ribosomal protein L7/L12	-
V6U64_RS07535 (V6U64_07535)	rplJ	1647167..1647670 (-)	504	WP_003095623.1	50S ribosomal protein L10	-

Sequence

Protein

• Length: 247 a.a.
• Molecular weight: 28652.06 Da
• Isoelectric Point: 6.2541

>NTDB_id=940457 V6U64_RS07515 WP_101799772.1 1643072..1643815(+) (comE/blpR) [Streptococcus salivarius strain KSS4]
MLNIFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLLDAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKALDDEDFYERVHLAIEYTMNKMGATIAQDSFTFETATAQVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADDRLFRCHRSFIVNPENIVKINKEEKMVVFENNNECPISRTKYKGLLE
KVKSLKS

Nucleotide

• Length: 744 bp

>NTDB_id=940457 V6U64_RS07515 WP_101799772.1 1643072..1643815(+) (comE/blpR) [Streptococcus salivarius strain KSS4]
TTGTTAAATATTTTTATTTTAGAAGACGAATTTTTACAACAAACGCGAATAGAGACCGTTATTAAGGATGTTATTGCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTTTGGAAAACCTAGCCAGCTACTTGATGCGATTACCGAAAGAGGTTCTC
ATCAACTTTTCTTTTTAGATATTGAAATTAAAGGAGAAGAAAAAAAGGGGCTAGACATTGCGAAAGAAATTCGAAAAAAA
GATCCTAATGCAACAATTGTTTTTGTAACAACACATTCAGAATTTATGCCAGTCACTTTTAAATATAGAGTTGCTGCACT
AGATTTTATCGATAAAGCTTTGGATGATGAAGATTTTTATGAACGTGTTCATTTAGCAATTGAATATACCATGAATAAAA
TGGGTGCTACTATTGCCCAAGATTCATTTACTTTTGAAACAGCTACGGCTCAAGTTCAAGTTCCTTTTAACAATATCTTA
TTTTTTGAAACGTCTCCAACAATACATAAAGTTATTTTGCATACTAAAGAAGAACGAATGGAGTTCTACGCCAGTATTTC
AGAAGTTGAACGAGCTGATGACCGCCTATTTAGATGCCATCGTTCATTTATCGTTAATCCTGAAAATATCGTTAAGATCA
ATAAAGAAGAGAAAATGGTAGTGTTTGAAAATAATAATGAATGTCCCATTTCCCGTACGAAATATAAGGGCCTCCTAGAA
AAAGTTAAATCTTTGAAAAGCTAA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-241)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.393	96.761	0.526
comE/comE1	Streptococcus equinus JB1	45.679	98.381	0.449
comE/comE2	Streptococcus equinus JB1	39.837	99.595	0.397
comE/comE2	Streptococcus gordonii strain NCTC7865	38.057	100	0.381
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.057	100	0.381