Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   V6U63_RS01535 Genome accession   NZ_CP145861
Coordinates   288667..289356 (+) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius strain KSS3     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 283667..294356
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U63_RS01510 (V6U63_01515) - 283899..284729 (+) 831 WP_002886584.1 energy-coupling factor transporter transmembrane component T family protein -
  V6U63_RS01515 (V6U63_01520) - 284819..285490 (-) 672 WP_022496217.1 potassium channel family protein -
  V6U63_RS01520 (V6U63_01525) - 285530..286894 (-) 1365 WP_022496218.1 TrkH family potassium uptake protein -
  V6U63_RS01525 (V6U63_01530) rsmG 286963..287676 (-) 714 WP_349955348.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6U63_RS01530 (V6U63_01535) - 287975..288511 (+) 537 WP_002883813.1 DUF177 domain-containing protein -
  V6U63_RS01535 (V6U63_01540) covR 288667..289356 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6U63_RS01540 (V6U63_01545) covS 289353..290882 (+) 1530 WP_002883784.1 HAMP domain-containing histidine kinase Regulator
  V6U63_RS01545 (V6U63_01550) nrdR 291004..291483 (+) 480 WP_073689471.1 transcriptional regulator NrdR -
  V6U63_RS01550 (V6U63_01555) - 291480..292655 (+) 1176 WP_129852167.1 DnaD domain protein -
  V6U63_RS01555 (V6U63_01560) dnaI 292659..293561 (+) 903 WP_002883792.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=940360 V6U63_RS01535 WP_002883757.1 288667..289356(+) (covR) [Streptococcus salivarius strain KSS3]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=940360 V6U63_RS01535 WP_002883757.1 288667..289356(+) (covR) [Streptococcus salivarius strain KSS3]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCCAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCTATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATTGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445