Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   V6U63_RS01540 Genome accession   NZ_CP145861
Coordinates   289353..290882 (+) Length   509 a.a.
NCBI ID   WP_002883784.1    Uniprot ID   A0A1V0GG48
Organism   Streptococcus salivarius strain KSS3     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 284353..295882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U63_RS01515 (V6U63_01520) - 284819..285490 (-) 672 WP_022496217.1 potassium channel family protein -
  V6U63_RS01520 (V6U63_01525) - 285530..286894 (-) 1365 WP_022496218.1 TrkH family potassium uptake protein -
  V6U63_RS01525 (V6U63_01530) rsmG 286963..287676 (-) 714 WP_349955348.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6U63_RS01530 (V6U63_01535) - 287975..288511 (+) 537 WP_002883813.1 DUF177 domain-containing protein -
  V6U63_RS01535 (V6U63_01540) covR 288667..289356 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6U63_RS01540 (V6U63_01545) covS 289353..290882 (+) 1530 WP_002883784.1 HAMP domain-containing histidine kinase Regulator
  V6U63_RS01545 (V6U63_01550) nrdR 291004..291483 (+) 480 WP_073689471.1 transcriptional regulator NrdR -
  V6U63_RS01550 (V6U63_01555) - 291480..292655 (+) 1176 WP_129852167.1 DnaD domain protein -
  V6U63_RS01555 (V6U63_01560) dnaI 292659..293561 (+) 903 WP_002883792.1 primosomal protein DnaI -
  V6U63_RS01560 (V6U63_01565) der 293666..294976 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  V6U63_RS01565 (V6U63_01570) - 295041..295670 (+) 630 WP_022495832.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58071.44 Da        Isoelectric Point: 5.1853

>NTDB_id=940361 V6U63_RS01540 WP_002883784.1 289353..290882(+) (covS) [Streptococcus salivarius strain KSS3]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=940361 V6U63_RS01540 WP_002883784.1 289353..290882(+) (covS) [Streptococcus salivarius strain KSS3]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCAGCCAATACGCTACTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCTAAAAATATCTATGCATCGATCATTAATGGAGTGCTTTCTGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGATTCGCCTCCAGGTATGTCCGAAGTAAATAAACTGAAGTCAGTATCCTATAAAGGGAAGCGTGGTTTC
CTGCTACAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGATTTTCTTATTGATTTTCCTCGAAGTGGGAATGACGGTCCTAGTTATTGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACACCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGGAAAAATGACCCTGAAATCCTTGAGGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCAGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTACAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAATC
GTACAACAACACAATCTGGTGTTGGTATTGGTTTGTCAATTCTTTACCAAATTGTGGAAGCTTATCGTTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCGGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0GG48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

100

100

1