Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   V6U62_RS03010 Genome accession   NZ_CP145860
Coordinates   576486..578360 (+) Length   624 a.a.
NCBI ID   WP_118189152.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS2     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 571486..583360
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U62_RS02995 (V6U62_02985) fmt 573458..574393 (+) 936 WP_002884812.1 methionyl-tRNA formyltransferase -
  V6U62_RS03000 (V6U62_02990) rsmB 574383..575705 (+) 1323 WP_002884194.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  V6U62_RS03005 (V6U62_02995) - 575749..576486 (+) 738 WP_037604753.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  V6U62_RS03010 (V6U62_03000) stkP/pknB 576486..578360 (+) 1875 WP_118189152.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  V6U62_RS03015 (V6U62_03005) - 578506..579264 (+) 759 WP_002884314.1 potassium channel family protein -
  V6U62_RS03020 (V6U62_03010) liaF 579429..580127 (+) 699 WP_175063017.1 cell wall-active antibiotics response protein LiaF -
  V6U62_RS03025 (V6U62_03015) - 580124..581134 (+) 1011 WP_175063016.1 sensor histidine kinase -
  V6U62_RS03030 (V6U62_03020) - 581124..581768 (+) 645 WP_022496266.1 response regulator transcription factor -
  V6U62_RS03045 (V6U62_03035) rimM 582463..582981 (+) 519 WP_002884411.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67999.69 Da        Isoelectric Point: 6.5790

>NTDB_id=940308 V6U62_RS03010 WP_118189152.1 576486..578360(+) (stkP/pknB) [Streptococcus salivarius strain KSS2]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNERVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVDGQELSTAQTKIEGAGFKVGEVKEV
EDDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDNAEEGE
ILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGVKLDKDKIPSSTEV
LYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=940308 V6U62_RS03010 WP_118189152.1 576486..578360(+) (stkP/pknB) [Streptococcus salivarius strain KSS2]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGGCGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGAGTAGCTATTAAGGTGCTACGTACCAATTACCAAACGGATCAGGTGG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTTTTGGTGATGGAGTATGTAGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTTACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACTAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
GAAAGCAACTATCCAAAGCGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GTGACAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCTATTTTGGCAGAGAACCGTAATGTTCCC
CAAGCCTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAGAATCGTTATAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCAAAGGTTGATCCAGTTCCATCTGCAAGTCTTGAGAAAAAAGCCGTTGCTGCTGAGCCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAAAAACTTTTTCTCAACCTTGCTCAAGGT
TTTCCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTGGTATTTACCAATCCTGATAATGTCCAGGTGCCTA
ATGTGGACGGTCAAGAGTTGTCCACAGCTCAGACTAAAATCGAGGGTGCTGGATTTAAGGTAGGAGAAGTTAAGGAAGTG
GAAGATGACTCTGTCGATACAGGCAAGGTCATCAAGACTGATCCTACAGCTGGAACCACACGAAAAGAGGGATCAAGCAT
TGATGTCTATGTTTCTTCTGGTAGTAAAGGTTTTGCGTTGAAAGACTACAAAGGTAAAAACTATAAGGATGCCATTGAGG
ACTTAACTTCGAATTATGGCGTTTCTGAGGATCAAATTGATATTCAGCATGTCGAAGACGATAATGCTGAAGAGGGAGAA
ATCCTATCTCAAAGTCCAGGAAAAAACAAGTCCTTCAACCCTAAGGATAGTAAGGCTAAAATCAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAGTATCT
CAAGTAGTAGCATCGAGTACCATGACTATAATACTGGTGTTAAGTTAGACAAGGATAAGATTCCTAGCAGTACAGAGGTC
CTTTATCAAGATCCACAAGCTGGTACAAGCGTTGATGGTACAGTGATCCTCTATGTTTCAGTTGCAACAGCAAGTTCAAG
TCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAGCTACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(511-580)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(370-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.558

100

0.986
  pknB Streptococcus mutans UA159

67.159

86.859

0.583
  stkP Streptococcus pneumoniae TIGR4

52.151

93.109

0.486
  stkP Streptococcus pneumoniae D39

51.979

93.109

0.484
  stkP Streptococcus pneumoniae R6

51.979

93.109

0.484
  stkP Streptococcus pneumoniae Rx1

51.807

93.109

0.482