Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   V6T26_RS03005 Genome accession   NZ_CP145858
Coordinates   577882..579753 (+) Length   623 a.a.
NCBI ID   WP_060972669.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS11     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 572882..584753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T26_RS02990 (V6T26_02990) fmt 574854..575789 (+) 936 WP_410541402.1 methionyl-tRNA formyltransferase -
  V6T26_RS02995 (V6T26_02995) rsmB 575779..577101 (+) 1323 WP_410541403.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  V6T26_RS03000 (V6T26_03000) - 577145..577882 (+) 738 WP_410541404.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  V6T26_RS03005 (V6T26_03005) stkP/pknB 577882..579753 (+) 1872 WP_060972669.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  V6T26_RS03010 (V6T26_03010) - 579898..580656 (+) 759 WP_410541405.1 ion channel -
  V6T26_RS03015 (V6T26_03015) liaF 580819..581517 (+) 699 WP_195968864.1 cell wall-active antibiotics response protein LiaF -
  V6T26_RS03020 (V6T26_03020) - 581514..582524 (+) 1011 WP_002891418.1 sensor histidine kinase -
  V6T26_RS03025 (V6T26_03025) - 582514..583154 (+) 641 Protein_575 response regulator -
  V6T26_RS03040 (V6T26_03040) rimM 583851..584369 (+) 519 WP_060972851.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67824.51 Da        Isoelectric Point: 6.5787

>NTDB_id=940243 V6T26_RS03005 WP_060972669.1 577882..579753(+) (stkP/pknB) [Streptococcus salivarius strain KSS11]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKIVFDDMTDTKTLPKVDPVPSASPEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGAGFKVGEVKEVE
DDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGEI
LSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAIQTLNRKNISSSSIEYHDYNTGAKLDKDKVPSSTEVL
YQDPQAGTSVDGTVILYVSVATASSNLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=940243 V6T26_RS03005 WP_060972669.1 577882..579753(+) (stkP/pknB) [Streptococcus salivarius strain KSS11]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATTCTGGATAATGAAAAAGTGGCTATTAAGGTACTTCGTACCAATTACCAAACTGATCAGGTGG
CTGTGGCCCGTTTCCAACGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTATGTGGACGGTTCGGACTTGAAGAAATACATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTCCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCGCAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACAAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
TAAAGCGACTATCCAAAGTGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GCGATAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAACCACTACCATCGATTTTGGCAGAGAACCGTAACGTTCCC
CAAGCTTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTACAATAGTACTTTGGAAATGAGTCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGATAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCGAAGGTTGATCCAGTTCCATCAGCAAGTCCTGAGAAAAAAGCCGTTGCTGCTGAACCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAACTTCTTCTCAACCTTACTCAAGGTTTT
CCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCTTATTTAGTCTTTACCAATCCTGATAATGTCCAAGTACCTAATG
TGGTCGGTCAGGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTCAAAGAAGTGGAA
GATGACTCTGTCGATACGGGTAAGGTCATCAAGACAGATCCTACAGCTGGAACCACACGAAAAGAAGGATCAAGCATTGA
TGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAGGGTAAAAACTATAAGGATGCCATTGAGGACT
TAACTTCGAATTATGGTGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAAATC
CTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCTAAGATTAAGTTCCGTGTGGCAACTCC
TAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGATTCAAACCTTGAATCGTAAGAATATCTCAA
GTAGTAGCATCGAGTACCACGACTATAATACTGGTGCCAAATTAGATAAGGATAAGGTTCCTAGCAGTACGGAGGTCCTT
TATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAGTTCAAACCT
TCAGTCAAGCTCAAGTAGTACGACACATTCGTCATCAACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAACCT
CGACAGAGGCTACTCACACAGAACTACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(369-431)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(440-504)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.237

100

0.984
  pknB Streptococcus mutans UA159

66.79

86.998

0.581
  stkP Streptococcus pneumoniae TIGR4

52.241

93.098

0.486
  stkP Streptococcus pneumoniae D39

52.069

93.098

0.485
  stkP Streptococcus pneumoniae R6

52.069

93.098

0.485
  stkP Streptococcus pneumoniae Rx1

51.897

93.098

0.483