Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   V6T01_RS07215 Genome accession   NZ_CP145856
Coordinates   1582667..1584538 (-) Length   623 a.a.
NCBI ID   WP_060972669.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS1     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1577667..1589538
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T01_RS07180 (V6T01_07155) rimM 1578047..1578565 (-) 519 WP_060972851.1 ribosome maturation factor RimM -
  V6T01_RS07195 (V6T01_07170) - 1579262..1579906 (-) 645 WP_002891417.1 response regulator transcription factor -
  V6T01_RS07200 (V6T01_07175) - 1579896..1580906 (-) 1011 WP_002891418.1 sensor histidine kinase -
  V6T01_RS07205 (V6T01_07180) liaF 1580903..1581601 (-) 699 WP_195968864.1 cell wall-active antibiotics response protein LiaF -
  V6T01_RS07210 (V6T01_07185) - 1581764..1582522 (-) 759 WP_410541405.1 ion channel -
  V6T01_RS07215 (V6T01_07190) stkP/pknB 1582667..1584538 (-) 1872 WP_060972669.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  V6T01_RS07220 (V6T01_07195) - 1584538..1585275 (-) 738 WP_410541404.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  V6T01_RS07225 (V6T01_07200) rsmB 1585319..1586641 (-) 1323 WP_410541403.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  V6T01_RS07230 (V6T01_07205) fmt 1586631..1587566 (-) 936 WP_410541402.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67824.51 Da        Isoelectric Point: 6.5787

>NTDB_id=940188 V6T01_RS07215 WP_060972669.1 1582667..1584538(-) (stkP/pknB) [Streptococcus salivarius strain KSS1]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKIVFDDMTDTKTLPKVDPVPSASPEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGAGFKVGEVKEVE
DDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGEI
LSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAIQTLNRKNISSSSIEYHDYNTGAKLDKDKVPSSTEVL
YQDPQAGTSVDGTVILYVSVATASSNLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=940188 V6T01_RS07215 WP_060972669.1 1582667..1584538(-) (stkP/pknB) [Streptococcus salivarius strain KSS1]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATTCTGGATAATGAAAAAGTGGCTATTAAGGTACTTCGTACCAATTACCAAACTGATCAGGTGG
CTGTGGCCCGTTTCCAACGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTATGTGGACGGTTCGGACTTGAAGAAATACATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTCCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCGCAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACAAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
TAAAGCGACTATCCAAAGTGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GCGATAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAACCACTACCATCGATTTTGGCAGAGAACCGTAACGTTCCC
CAAGCTTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTACAATAGTACTTTGGAAATGAGTCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGATAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCGAAGGTTGATCCAGTTCCATCAGCAAGTCCTGAGAAAAAAGCCGTTGCTGCTGAACCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAACTTCTTCTCAACCTTACTCAAGGTTTT
CCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCTTATTTAGTCTTTACCAATCCTGATAATGTCCAAGTACCTAATG
TGGTCGGTCAGGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTCAAAGAAGTGGAA
GATGACTCTGTCGATACGGGTAAGGTCATCAAGACAGATCCTACAGCTGGAACCACACGAAAAGAAGGATCAAGCATTGA
TGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAGGGTAAAAACTATAAGGATGCCATTGAGGACT
TAACTTCGAATTATGGTGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAAATC
CTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCTAAGATTAAGTTCCGTGTGGCAACTCC
TAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGATTCAAACCTTGAATCGTAAGAATATCTCAA
GTAGTAGCATCGAGTACCACGACTATAATACTGGTGCCAAATTAGATAAGGATAAGGTTCCTAGCAGTACGGAGGTCCTT
TATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAGTTCAAACCT
TCAGTCAAGCTCAAGTAGTACGACACATTCGTCATCAACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAACCT
CGACAGAGGCTACTCACACAGAACTACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(369-431)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(440-504)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.237

100

0.984
  pknB Streptococcus mutans UA159

66.79

86.998

0.581
  stkP Streptococcus pneumoniae TIGR4

52.241

93.098

0.486
  stkP Streptococcus pneumoniae D39

52.069

93.098

0.485
  stkP Streptococcus pneumoniae R6

52.069

93.098

0.485
  stkP Streptococcus pneumoniae Rx1

51.897

93.098

0.483