Detailed information NTG0939016

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ORY85_RS08345
• Genome accession: NZ_CP145606
• Coordinates: 1747004..1748161 (+)
• Length: 385 a.a.
• NCBI ID: WP_274571708.1
• Uniprot ID: A0A9X4E1M1
• Organism: Neisseria leonii strain 3986
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1742004..1753161

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ORY85_RS08325 (ORY85_08325)	-	1743547..1744152 (-)	606	WP_274571704.1	DUF4390 domain-containing protein	-
ORY85_RS08330 (ORY85_08330)	rsmB	1744118..1745377 (-)	1260	WP_274571705.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
ORY85_RS08335 (ORY85_08335)	fmt	1745374..1746300 (-)	927	WP_274571706.1	methionyl-tRNA formyltransferase	-
ORY85_RS08340 (ORY85_08340)	def	1746369..1746869 (-)	501	WP_274571707.1	peptide deformylase	-
ORY85_RS08345 (ORY85_08345)	dprA	1747004..1748161 (+)	1158	WP_274571708.1	DNA-processing protein DprA	Machinery gene
ORY85_RS08350 (ORY85_08350)	-	1748243..1748698 (+)	456	WP_274571709.1	DUF494 family protein	-
ORY85_RS08355 (ORY85_08355)	topA	1748791..1751100 (+)	2310	WP_274571710.1	type I DNA topoisomerase	-
ORY85_RS08360 (ORY85_08360)	-	1751174..1751512 (-)	339	WP_274571711.1	hypothetical protein	-
ORY85_RS08365 (ORY85_08365)	-	1751532..1751864 (-)	333	WP_274571712.1	hypothetical protein	-
ORY85_RS08370 (ORY85_08370)	-	1752005..1752379 (+)	375	WP_274571713.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 40087.61 Da
• Isoelectric Point: 6.4978

>NTDB_id=939016 ORY85_RS08345 WP_274571708.1 1747004..1748161(+) (dprA) [Neisseria leonii strain 3986]
MQQEERDAWLCLALLPQVGADTFARLLAHFGSARSAWRAGIGEAEICLPRSAAREAWRNRRAEAEAAAEAALAWVRETEN
ARLLLSCDPDFPLMLHEGITPPPLLFVRGNVAMLHRPALAVVGSRHATPQALRIARDFSQALSAAGIVVVSGMASGIDTA
AHQGALAGGGGTAAVWGTGIDRVYPAANRSLAHDIAASGVIVSEFPLGARPLAGHFPRRNRIIAALAQAVLVVEAAVESG
SLITARLAAEMGREVLAVPGSIDNPHSKGCHKLIKDGAKLTECLEDILIECPGLLQTARSSAYAIKNNAPPDGGGAERPQ
AVFQTAGSGGDGDGLLDAMGFDSVHPDSLAERLNRPAADVYAGLLELELAGRVAAAGGGRYQRTG

Nucleotide

• Length: 1158 bp

>NTDB_id=939016 ORY85_RS08345 WP_274571708.1 1747004..1748161(+) (dprA) [Neisseria leonii strain 3986]
ATGCAGCAGGAAGAACGTGATGCGTGGTTGTGTCTGGCTTTGTTGCCGCAGGTTGGGGCGGATACGTTCGCACGTCTGCT
GGCACATTTCGGTTCGGCACGTTCGGCATGGCGCGCAGGGATTGGCGAAGCGGAAATCTGCCTGCCGCGCAGCGCGGCGC
GCGAAGCCTGGCGCAACCGCCGCGCCGAAGCCGAAGCTGCGGCCGAAGCGGCACTGGCTTGGGTGCGCGAAACCGAAAAC
GCCCGCCTGCTGCTCTCTTGCGACCCCGATTTTCCGCTCATGCTCCACGAAGGCATCACCCCGCCTCCGCTGCTGTTTGT
CCGCGGCAATGTAGCGATGCTGCACCGCCCCGCGCTGGCGGTAGTCGGCAGCCGCCATGCCACGCCGCAGGCTCTGCGTA
TCGCGCGCGACTTTTCGCAGGCTTTGTCGGCAGCGGGGATAGTAGTGGTTTCGGGCATGGCTTCCGGCATCGACACCGCC
GCCCATCAGGGCGCGCTGGCGGGCGGCGGCGGAACCGCAGCCGTGTGGGGGACGGGCATCGACCGCGTTTACCCCGCCGC
CAACCGCAGTCTGGCACACGATATTGCCGCATCGGGCGTGATTGTGTCGGAATTTCCGCTCGGCGCGCGGCCGCTGGCCG
GGCATTTCCCGCGCCGCAACCGCATCATCGCCGCCTTGGCGCAGGCGGTACTGGTGGTGGAGGCGGCCGTCGAATCCGGT
TCGCTGATTACTGCGCGGCTGGCCGCCGAAATGGGCCGAGAAGTGCTGGCCGTGCCGGGTTCCATCGACAACCCGCACAG
CAAAGGCTGCCACAAGCTGATTAAAGACGGCGCAAAATTGACCGAATGTCTGGAAGATATTCTGATAGAGTGTCCGGGGC
TATTGCAAACCGCCCGATCTTCGGCATATGCTATAAAAAATAACGCGCCGCCCGATGGCGGCGGGGCAGAGCGGCCGCAG
GCCGTTTTTCAGACGGCCGGAAGCGGCGGCGACGGGGACGGGCTGCTGGACGCGATGGGCTTTGATTCGGTACACCCAGA
CAGTCTGGCCGAGCGTCTCAACCGCCCCGCAGCCGATGTTTATGCCGGATTGCTGGAATTGGAGTTGGCCGGCAGGGTGG
CGGCGGCGGGCGGCGGCCGTTACCAGCGTACCGGCTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (329-379)

• DNA recombination-mediator protein A (DNA_processg_A) (78-281)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae strain FA1090	60.969	100	0.621
dprA	Neisseria gonorrhoeae MS11	60.714	100	0.618
dprA	Neisseria meningitidis strain C311	59	100	0.613
dprA	Neisseria meningitidis MC58	59	100	0.613
dprA	Vibrio cholerae strain A1552	38.987	100	0.4
dprA	Vibrio campbellii strain DS40M4	39.153	98.182	0.384