Detailed information NTG0938720

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: LBA42_RS08060
• Genome accession: NZ_CP145437
• Coordinates: 1596268..1596570 (+)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain HAC 39-1996
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1591268..1601570

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LBA42_RS08030 (LBA42_08030)	-	1592028..1593086 (+)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
LBA42_RS08035 (LBA42_08035)	-	1593237..1593602 (+)	366	WP_000286415.1	DUF1033 family protein	-
LBA42_RS08040 (LBA42_08040)	comGA/cglA/cilD	1593678..1594619 (+)	942	WP_000249536.1	competence type IV pilus ATPase ComGA	Machinery gene
LBA42_RS08045 (LBA42_08045)	comGB/cglB	1594567..1595583 (+)	1017	WP_078130737.1	competence type IV pilus assembly protein ComGB	Machinery gene
LBA42_RS08050 (LBA42_08050)	comGC/cglC	1595585..1595908 (+)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
LBA42_RS08055 (LBA42_08055)	comGD/cglD	1595871..1596305 (+)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
LBA42_RS08060 (LBA42_08060)	comGE/cglE	1596268..1596570 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
LBA42_RS08065 (LBA42_08065)	comGF/cglF	1596533..1596994 (+)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
LBA42_RS08070 (LBA42_08070)	comGG/cglG	1596972..1597418 (+)	447	WP_001809944.1	competence type IV pilus minor pilin ComGG	Machinery gene
LBA42_RS08075 (LBA42_08075)	-	1597521..1598113 (+)	593	Protein_1580	methyltransferase domain-containing protein	-
LBA42_RS08080 (LBA42_08080)	comYH	1598174..1599127 (+)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
LBA42_RS08085 (LBA42_08085)	-	1599178..1600368 (+)	1191	WP_000167765.1	acetate kinase	-
LBA42_RS08090 (LBA42_08090)	-	1600369..1600500 (+)	132	WP_000768904.1	hypothetical protein	-
LBA42_RS08095 (LBA42_08095)	rnpA	1600517..1600888 (+)	372	WP_000739246.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=938720 LBA42_RS08060 WP_000413382.1 1596268..1596570(+) (comGE/cglE) [Streptococcus pneumoniae strain HAC 39-1996]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=938720 LBA42_RS08060 WP_000413382.1 1596268..1596570(+) (comGE/cglE) [Streptococcus pneumoniae strain HAC 39-1996]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4