Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   LBA42_RS08080 Genome accession   NZ_CP145437
Coordinates   1598174..1599127 (+) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain HAC 39-1996     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1593174..1604127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LBA42_RS08035 (LBA42_08035) - 1593237..1593602 (+) 366 WP_000286415.1 DUF1033 family protein -
  LBA42_RS08040 (LBA42_08040) comGA/cglA/cilD 1593678..1594619 (+) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  LBA42_RS08045 (LBA42_08045) comGB/cglB 1594567..1595583 (+) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  LBA42_RS08050 (LBA42_08050) comGC/cglC 1595585..1595908 (+) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  LBA42_RS08055 (LBA42_08055) comGD/cglD 1595871..1596305 (+) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  LBA42_RS08060 (LBA42_08060) comGE/cglE 1596268..1596570 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  LBA42_RS08065 (LBA42_08065) comGF/cglF 1596533..1596994 (+) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  LBA42_RS08070 (LBA42_08070) comGG/cglG 1596972..1597418 (+) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  LBA42_RS08075 (LBA42_08075) - 1597521..1598113 (+) 593 Protein_1580 methyltransferase domain-containing protein -
  LBA42_RS08080 (LBA42_08080) comYH 1598174..1599127 (+) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  LBA42_RS08085 (LBA42_08085) - 1599178..1600368 (+) 1191 WP_000167765.1 acetate kinase -
  LBA42_RS08090 (LBA42_08090) - 1600369..1600500 (+) 132 WP_000768904.1 hypothetical protein -
  LBA42_RS08095 (LBA42_08095) rnpA 1600517..1600888 (+) 372 WP_000739246.1 ribonuclease P protein component -
  LBA42_RS08100 (LBA42_08100) - 1600863..1601687 (+) 825 WP_000727904.1 membrane protein insertase YidC -
  LBA42_RS08105 (LBA42_08105) jag 1601706..1602692 (+) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  LBA42_RS08110 (LBA42_08110) - 1602743..1603366 (+) 624 WP_000932658.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=938723 LBA42_RS08080 WP_000345126.1 1598174..1599127(+) (comYH) [Streptococcus pneumoniae strain HAC 39-1996]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=938723 LBA42_RS08080 WP_000345126.1 1598174..1599127(+) (comYH) [Streptococcus pneumoniae strain HAC 39-1996]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536