Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   V4S29_RS11135 Genome accession   NZ_CP144498
Coordinates   2196344..2197591 (+) Length   415 a.a.
NCBI ID   WP_208922427.1    Uniprot ID   -
Organism   Enterococcus cecorum strain 66     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2191344..2202591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V4S29_RS11110 (V4S29_11115) - 2191497..2192246 (-) 750 WP_191465208.1 NADPH-dependent oxidoreductase -
  V4S29_RS11115 (V4S29_11120) - 2192249..2193349 (-) 1101 WP_243171260.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  V4S29_RS11120 (V4S29_11125) - 2193375..2194553 (-) 1179 WP_243171261.1 MalY/PatB family protein -
  V4S29_RS11125 (V4S29_11130) - 2194701..2195399 (-) 699 WP_171299580.1 hydrolase -
  V4S29_RS11130 (V4S29_11135) rlmH 2195407..2195886 (-) 480 WP_016251475.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  V4S29_RS11135 (V4S29_11140) htrA 2196344..2197591 (+) 1248 WP_208922427.1 trypsin-like peptidase domain-containing protein Regulator
  V4S29_RS11140 (V4S29_11145) - 2197832..2198488 (-) 657 WP_047242864.1 Crp/Fnr family transcriptional regulator -
  V4S29_RS11145 (V4S29_11150) - 2198858..2200087 (+) 1230 WP_087403230.1 MFS transporter -
  V4S29_RS11150 (V4S29_11155) - 2200090..2200260 (+) 171 WP_171311431.1 hypothetical protein -
  V4S29_RS11155 (V4S29_11160) ytpR 2200327..2200938 (-) 612 WP_171299583.1 YtpR family tRNA-binding protein -
  V4S29_RS11160 (V4S29_11165) - 2201018..2201623 (-) 606 WP_171299595.1 CadD family cadmium resistance transporter -
  V4S29_RS11165 (V4S29_11170) - 2201665..2202108 (-) 444 WP_243171647.1 universal stress protein -
  V4S29_RS11170 (V4S29_11175) - 2202131..2202442 (-) 312 WP_171299585.1 thioredoxin family protein -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43263.28 Da        Isoelectric Point: 5.7751

>NTDB_id=934127 V4S29_RS11135 WP_208922427.1 2196344..2197591(+) (htrA) [Enterococcus cecorum strain 66]
MSRRKNSNTIMKRFGIGICSGVIGGALAFGGLYAVTGMNHTTSSTGIQSAQTATKVKNVKYNVESDVTKAVSKVQGAVVS
IINLQNQNAQGTGSLEDFFGAQQGNSSSQNSGTLETASEGSGVIYKKEGKYAYIVTNNHVVEGQNALQVLLADGTKVDAE
LVGTDSYTDLAVIKIASDKVSTVATFGDSDNLKVGEPAIAIGSPLGTDYANSVTEGIISSLNRQVVSENDSGQEVNINAI
QTDAAINPGNSGGPLINIAGQVIGINSSKIATTSTSSSGVSVEGMGFAIPSNDVVNIINQLEQSGKVTRPALGVRTVDLN
ALSDQQKTNILKVPTSLNEGVVLAQVNSATPAEKAGLKQYDVITEIDGKKVNDGTELRAALYKKHVGDSIKVTYYRGNDK
KTTTVHLTVDQSINE

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=934127 V4S29_RS11135 WP_208922427.1 2196344..2197591(+) (htrA) [Enterococcus cecorum strain 66]
ATGAGTAGAAGAAAAAATTCAAATACAATTATGAAAAGATTTGGTATCGGCATTTGTAGCGGTGTGATTGGTGGTGCTCT
TGCTTTTGGCGGCTTGTATGCAGTCACTGGAATGAATCATACGACTAGCTCAACAGGTATTCAAAGTGCACAAACAGCAA
CTAAAGTTAAAAATGTGAAATATAATGTAGAAAGCGACGTAACAAAAGCGGTCTCTAAAGTACAAGGTGCAGTCGTTTCA
ATCATTAATTTACAAAATCAAAACGCACAAGGCACGGGCAGTTTAGAAGATTTCTTTGGTGCCCAACAAGGAAATAGTAG
CAGTCAAAATAGCGGTACTTTGGAAACAGCCAGTGAAGGTAGTGGCGTCATTTATAAAAAAGAAGGTAAATATGCTTATA
TCGTGACAAATAATCACGTGGTTGAAGGTCAAAATGCATTACAAGTCTTACTAGCAGACGGTACCAAAGTCGATGCTGAA
TTAGTTGGTACGGACAGCTATACTGACTTAGCGGTAATCAAGATTGCTAGCGATAAAGTTTCAACGGTTGCTACTTTTGG
CGATTCAGATAATCTAAAAGTTGGTGAACCTGCCATCGCCATCGGATCACCATTAGGAACCGATTATGCCAACTCAGTGA
CTGAAGGAATTATTTCTTCTTTAAATCGTCAAGTCGTGAGTGAAAATGATTCCGGCCAAGAAGTTAATATCAACGCTATC
CAAACTGATGCAGCGATTAACCCTGGTAACTCTGGTGGTCCATTAATTAATATCGCCGGTCAAGTTATCGGAATTAACTC
AAGTAAAATTGCTACCACTTCAACCTCAAGCTCTGGTGTAAGTGTTGAAGGTATGGGCTTTGCAATTCCAAGTAATGATG
TCGTCAATATTATTAACCAACTAGAACAAAGTGGGAAAGTGACTCGTCCTGCTTTAGGGGTTAGAACGGTTGATTTGAAT
GCTTTATCTGATCAACAAAAAACGAACATCTTAAAAGTACCTACCTCATTAAATGAAGGGGTCGTGCTTGCTCAAGTCAA
CAGTGCAACGCCTGCAGAAAAAGCGGGCTTGAAACAATATGATGTCATTACTGAAATTGATGGTAAAAAGGTCAATGATG
GCACTGAATTAAGAGCCGCTCTTTATAAAAAACATGTCGGTGACAGCATTAAAGTGACTTACTATCGTGGCAATGACAAA
AAGACAACCACCGTACACCTTACCGTCGACCAATCAATTAATGAATAA

Domains

Predicted by InterProScan.

Peptidase family M50 (Peptidase_M50)

(251-410)

PDZ domain (PDZ_2)

(310-407)

Trypsin-like peptidase domain (Trypsin_2)

(120-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.742

85.783

0.487
  htrA Streptococcus pneumoniae Rx1

48.775

98.313

0.48
  htrA Streptococcus pneumoniae D39

48.775

98.313

0.48
  htrA Streptococcus pneumoniae R6

48.775

98.313

0.48
  htrA Streptococcus pneumoniae TIGR4

48.775

98.313

0.48
  htrA Streptococcus gordonii str. Challis substr. CH1

48.894

98.072

0.48
  htrA Streptococcus mitis NCTC 12261

50.394

91.807

0.463