Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   V4S27_RS01950 Genome accession   NZ_CP144495
Coordinates   383369..384616 (-) Length   415 a.a.
NCBI ID   WP_347915211.1    Uniprot ID   -
Organism   Enterococcus cecorum strain 70     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 378369..389616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V4S27_RS01915 (V4S27_01915) - 378379..378690 (+) 312 WP_016251466.1 thioredoxin family protein -
  V4S27_RS01920 (V4S27_01920) - 378713..379156 (+) 444 WP_171333327.1 universal stress protein -
  V4S27_RS01925 (V4S27_01925) - 379201..379803 (+) 603 WP_080961497.1 CadD family cadmium resistance transporter -
  V4S27_RS01930 (V4S27_01930) ytpR 379882..380493 (+) 612 WP_047334171.1 YtpR family tRNA-binding protein -
  V4S27_RS01935 (V4S27_01935) - 380701..380871 (-) 171 WP_167541418.1 hypothetical protein -
  V4S27_RS01940 (V4S27_01940) - 380874..382103 (-) 1230 WP_047242911.1 MFS transporter -
  V4S27_RS01945 (V4S27_01945) - 382472..383128 (+) 657 WP_047242864.1 Crp/Fnr family transcriptional regulator -
  V4S27_RS01950 (V4S27_01950) htrA 383369..384616 (-) 1248 WP_347915211.1 trypsin-like peptidase domain-containing protein Regulator
  V4S27_RS01955 (V4S27_01955) rlmH 385073..385552 (+) 480 WP_016251475.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  V4S27_RS01960 (V4S27_01960) - 385560..386258 (+) 699 WP_047338837.1 hydrolase -
  V4S27_RS01965 (V4S27_01965) - 386406..387584 (+) 1179 WP_047334169.1 MalY/PatB family protein -
  V4S27_RS01970 (V4S27_01970) - 387611..388711 (+) 1101 WP_347915213.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  V4S27_RS01975 (V4S27_01975) - 388714..389463 (+) 750 WP_347915214.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43176.20 Da        Isoelectric Point: 5.7703

>NTDB_id=934057 V4S27_RS01950 WP_347915211.1 383369..384616(-) (htrA) [Enterococcus cecorum strain 70]
MSRRKNSNTIMKRFGIGICSGVIGGALAFGGLYAVTGMNHTTSSTGIQSAQTATKVKNVKYNVESDVTKAVSKVQGAVVS
IINLQNQNAQGTGSLEDFFGAQQGNSSSQNSGTLETASEGSGVIYKKEGKHAYIVTNNHVVEGQNALQVLLADGTKVDAE
LVGTDSYTDLAVIKIASYKVSTVATFGDSDSLKVGEPAIAIGSPLGTDYANSVTEGIISSLNRQVVSENDSGQEVNINAI
QTDAAINPGNSGGPLINIAGQVIGINSSKIATTSTSSSGVSVEGMGFAIPSNDVVNIINQLEQSGKVTRPALGVRTVDLN
ALSDQQKTNILKVPASLNEGVVLAQVNSATPAEKAGLKQYDVITEIDGEKINDGTALRAALYKKQVGDSIKVTYYRGNDK
KTTTVHLTVDQSINE

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=934057 V4S27_RS01950 WP_347915211.1 383369..384616(-) (htrA) [Enterococcus cecorum strain 70]
ATGAGTAGAAGAAAAAATTCAAATACAATTATGAAAAGATTTGGTATCGGCATTTGTAGCGGTGTAATTGGTGGTGCCCT
TGCTTTTGGCGGCTTGTATGCAGTCACTGGAATGAATCATACGACTAGCTCAACAGGTATTCAAAGTGCACAAACAGCAA
CTAAAGTTAAAAATGTGAAATATAATGTAGAAAGCGACGTAACAAAAGCGGTCTCTAAAGTACAAGGTGCAGTCGTTTCA
ATCATTAATTTACAAAATCAAAACGCACAAGGCACGGGCAGTTTAGAAGATTTCTTTGGTGCCCAACAAGGAAATAGTAG
CAGTCAAAATAGCGGTACTTTGGAAACAGCCAGTGAAGGTAGTGGTGTCATTTATAAAAAAGAAGGTAAACATGCTTATA
TCGTGACAAATAATCACGTGGTTGAAGGTCAAAATGCATTACAAGTCTTACTAGCAGACGGTACCAAAGTCGATGCTGAA
TTAGTTGGTACGGACAGCTATACTGACTTAGCGGTAATCAAGATTGCTAGCTATAAAGTTTCAACGGTTGCTACTTTTGG
AGATTCAGATAGTCTAAAAGTTGGTGAACCTGCCATCGCCATCGGATCACCATTAGGAACTGATTATGCCAACTCAGTGA
CTGAAGGAATTATTTCTTCTTTAAATCGTCAAGTCGTGAGTGAAAATGATTCCGGTCAAGAAGTCAATATCAATGCCATC
CAAACTGATGCAGCGATTAACCCTGGTAACTCTGGTGGTCCATTAATTAATATCGCCGGTCAAGTTATCGGAATTAACTC
AAGTAAAATTGCTACCACTTCAACCTCAAGCTCTGGTGTAAGTGTTGAAGGTATGGGCTTTGCAATTCCAAGTAATGATG
TCGTCAATATTATTAACCAACTAGAACAAAGTGGGAAAGTAACTCGTCCTGCTTTAGGGGTTAGAACGGTTGATTTGAAT
GCTTTATCTGATCAACAAAAAACAAACATCTTAAAAGTACCTGCCTCATTAAATGAAGGTGTCGTGCTTGCTCAAGTCAA
TAGCGCAACGCCTGCAGAAAAAGCTGGCTTGAAACAATATGATGTCATTACTGAAATTGATGGTGAAAAGATCAATGATG
GCACTGCATTAAGAGCCGCGCTTTATAAAAAACAAGTCGGTGACAGCATTAAAGTGACTTACTATCGTGGCAATGACAAA
AAGACAACCACCGTACACCTTACCGTCGACCAATCAATTAATGAATAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(251-410)

PDZ domain (PDZ_2)

(310-407)

Trypsin-like peptidase domain (Trypsin_2)

(120-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.18

85.783

0.482
  htrA Streptococcus pneumoniae Rx1

48.775

98.313

0.48
  htrA Streptococcus pneumoniae D39

48.775

98.313

0.48
  htrA Streptococcus pneumoniae R6

48.775

98.313

0.48
  htrA Streptococcus pneumoniae TIGR4

48.775

98.313

0.48
  htrA Streptococcus gordonii str. Challis substr. CH1

48.649

98.072

0.477
  htrA Streptococcus mitis NCTC 12261

50.394

91.807

0.463