Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   V4S36_RS11235 Genome accession   NZ_CP144490
Coordinates   2159400..2160647 (+) Length   415 a.a.
NCBI ID   WP_171309753.1    Uniprot ID   -
Organism   Enterococcus cecorum strain 127     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2154400..2165647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V4S36_RS11210 (V4S36_11210) - 2154552..2155300 (-) 749 Protein_2165 NADPH-dependent oxidoreductase -
  V4S36_RS11215 (V4S36_11215) - 2155303..2156403 (-) 1101 WP_347943697.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  V4S36_RS11220 (V4S36_11220) - 2156430..2157608 (-) 1179 WP_347943698.1 MalY/PatB family protein -
  V4S36_RS11225 (V4S36_11225) - 2157756..2158454 (-) 699 WP_171299580.1 hydrolase -
  V4S36_RS11230 (V4S36_11230) rlmH 2158462..2158941 (-) 480 WP_016251475.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  V4S36_RS11235 (V4S36_11235) htrA 2159400..2160647 (+) 1248 WP_171309753.1 trypsin-like peptidase domain-containing protein Regulator
  V4S36_RS11240 (V4S36_11240) - 2160888..2161544 (-) 657 WP_047242864.1 Crp/Fnr family transcriptional regulator -
  V4S36_RS11245 (V4S36_11245) - 2162381..2162584 (+) 204 WP_347943699.1 hypothetical protein -
  V4S36_RS11250 (V4S36_11250) - 2162607..2163335 (-) 729 WP_347943700.1 peptidoglycan amidohydrolase family protein -
  V4S36_RS11255 (V4S36_11255) - 2163349..2163609 (-) 261 WP_347943702.1 hypothetical protein -
  V4S36_RS11260 (V4S36_11260) - 2163682..2164863 (-) 1182 WP_347943703.1 hypothetical protein -
  V4S36_RS11265 (V4S36_11265) - 2164856..2165239 (-) 384 WP_171315341.1 phage holin family protein -
  V4S36_RS11270 (V4S36_11270) - 2165322..2165633 (-) 312 WP_347943514.1 hypothetical protein -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43206.15 Da        Isoelectric Point: 5.7238

>NTDB_id=934045 V4S36_RS11235 WP_171309753.1 2159400..2160647(+) (htrA) [Enterococcus cecorum strain 127]
MSRRKNSNTIMKRFGIGICSGVIGGALAFGGLYAVTGMNHTTSSTGIQSAQTATKVQNAKYNVESDVTKAVSKVQGAVVS
IINLQNQNAQGTGGLEDFFGAQQGNSSNQNSGTLETASEGSGVIYKKEGKHAYIVTNNHVVEGQNALQVLLADGTKVDAE
LVGTDSYTDLAVIKIASDKVSTVATFGDSDNLKVGEPAIAIGSPLGTDYANSVTEGIISSLNRQVVSENDSGQEVNINAI
QTDAAINPGNSGGPLINIAGQVIGINSSKIATTSTSSSGVSVEGMGFAIPSNDVVNIINQLEQSGKVTRPALGVRTVDLN
ALSDQQKTNILKVPTSLNEGVVLAQVNSATPAEKAGLKQYDVITEIDGKKVNDGTELRAALYKKHVGDSIKVTYYRGNDK
KTTTVHLTVDQSINE

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=934045 V4S36_RS11235 WP_171309753.1 2159400..2160647(+) (htrA) [Enterococcus cecorum strain 127]
ATGAGTAGAAGAAAAAATTCAAATACAATTATGAAAAGATTTGGTATTGGCATTTGTAGCGGTGTGATTGGTGGTGCCCT
TGCTTTTGGCGGCTTGTATGCAGTCACTGGAATGAATCATACGACTAGCTCAACAGGTATTCAAAGTGCACAAACAGCAA
CTAAAGTTCAAAATGCGAAATATAATGTAGAAAGCGACGTAACAAAAGCGGTCTCTAAAGTACAAGGTGCAGTCGTTTCA
ATCATTAATTTACAAAATCAAAACGCACAAGGCACGGGCGGTTTAGAAGATTTCTTTGGTGCCCAACAAGGAAATAGTAG
CAATCAAAATAGCGGCACTTTGGAAACAGCCAGTGAAGGTAGTGGCGTCATTTATAAAAAAGAAGGTAAACATGCTTATA
TCGTGACAAATAATCACGTGGTTGAAGGTCAAAATGCATTACAAGTCTTACTAGCAGACGGTACCAAAGTCGATGCTGAA
TTAGTTGGTACGGACAGCTATACTGACTTAGCGGTAATCAAGATTGCTAGCGATAAAGTTTCAACGGTTGCTACTTTTGG
CGATTCAGATAATCTAAAAGTTGGTGAACCTGCCATCGCCATCGGATCACCATTAGGAACCGATTATGCCAACTCAGTGA
CTGAAGGAATTATTTCTTCTTTAAATCGTCAAGTCGTGAGTGAAAATGATTCCGGCCAAGAAGTTAATATCAACGCTATC
CAAACTGATGCAGCGATTAACCCTGGTAACTCTGGTGGTCCATTAATTAATATCGCCGGTCAAGTTATCGGAATTAACTC
AAGTAAAATTGCTACCACTTCAACCTCAAGCTCTGGTGTAAGTGTTGAAGGTATGGGCTTTGCAATTCCAAGTAATGATG
TCGTCAATATTATTAACCAACTAGAACAAAGTGGGAAAGTGACTCGTCCTGCTTTAGGGGTTAGAACGGTTGATTTGAAT
GCTTTATCTGATCAACAAAAAACGAACATCTTAAAAGTACCTACCTCATTAAATGAAGGGGTCGTGCTTGCTCAAGTCAA
CAGTGCAACGCCTGCAGAAAAAGCGGGCTTGAAACAATATGATGTCATTACTGAAATTGATGGTAAAAAGGTCAATGATG
GCACTGAATTAAGAGCCGCTCTTTATAAAAAACATGTCGGTGACAGCATTAAAGTGACTTACTATCGTGGCAATGACAAA
AAGACAACCACCGTACACCTTACCGTCGACCAATCAATTAATGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(310-407)

Peptidase family M50 (Peptidase_M50)

(251-410)

Trypsin-like peptidase domain (Trypsin_2)

(120-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.71

86.506

0.482
  htrA Streptococcus gordonii str. Challis substr. CH1

48.894

98.072

0.48
  htrA Streptococcus pneumoniae R6

48.529

98.313

0.477
  htrA Streptococcus pneumoniae TIGR4

48.529

98.313

0.477
  htrA Streptococcus pneumoniae D39

48.529

98.313

0.477
  htrA Streptococcus pneumoniae Rx1

48.529

98.313

0.477
  htrA Streptococcus mitis NCTC 12261

50.131

91.807

0.46